A. M. Sims
University of Queensland
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Publication
Featured researches published by A. M. Sims.
Current Molecular Medicine | 2004
A. M. Sims; B. P. Wordsworth; Matthew A. Brown
Ankylosing spondylitis is a highly heritable, common rheumatic condition, primarily affecting the axial skeleton. The association with HLA-B27 has been demonstrated worldwide, and evidence for a role of HLA-B27 in disease comes from linkage and association studies in humans, and transgenic animal models. However, twin studies indicate that HLA-B27 contributes only 16% of the total genetic risk for disease. Furthermore, there is compelling evidence that non-B27 genes, both within and outwith the major histocompatability complex, are involved in disease aetiology. In this post-genomic era we have the tools to help elicit the genetic basis of disease. This review describes methods for genetic investigation of ankylosing spondylitis, and summarises the status of current research in this exciting area.
Rheumatology | 2005
Sinead Harney; C. Meisel; A. M. Sims; Py Woon; B. P. Wordsworth; Matthew A. Brown
Rheumatology | 2004
E. Jaakkola; A. M. Crane; Kari Laiho; I. Herzberg; A. M. Sims; Linda A. Bradbury; Andrei Calin; Sinead Brophy; Markku Kauppi; K. Kaarela; B. P. Wordsworth; Jaakko Tuomilehto; Matthew A. Brown
Journal of Bone and Mineral Research | 2008
A. M. Sims; N. Shephard; Kim W. Carter; Tracey Doan; Alison Dowling; Emma L. Duncan; John A. Eisman; Graeme Jones; Geoff Nicholson; Richard L. Prince; Ego Seeman; Gethin P. Thomas; John Wass; Matthew A. Brown
The Journal of Rheumatology | 2008
J. J. Pointon; Kay Chapman; David Harvey; A. M. Sims; Linda A. Bradbury; Kari Laiho; Markku Kauppi; K. Kaarela; Jaakko Tuomilehto; Matthew A. Brown; B. P. Wordsworth
Fifth International Congress on Spondyloarthropathies | 2006
A. M. Sims; J. J. Pointon; Andrew E. Timms; Linda A. Bradbury; B. P. Wordsworth; Matthew A. Brown
The Journal of Rheumatology | 2011
J. J. Pointon; Kay Chapman; David Harvey; A. M. Sims; Linda A. Bradbury; Kari Laiho; Markku Kauppi; K. Kaarela; Jaakko Tuomilehto; Matthew A. Brown; B. P. Wordsworth
Faculty of Health; Institute of Health and Biomedical Innovation | 2011
J. J. Pointon; Kay Chapman; David Harvey; A. M. Sims; Linda A. Bradbury; Kari Laiho; Markku Kauppi; K. Kaarela; J. Tuomilehto; Matthew A. Brown; B. P. Wordsworth
Faculty of Health; Institute of Health and Biomedical Innovation | 2010
John D. Reveille; A. M. Sims; Patrick Danoy; David Evans; Paul Leo; J. J. Pointon; R. Jin; Xuezhong Zhou; Linda A. Bradbury; L. H. Appleton; John C. Davis; Laura Diekman; Tracy Doan; Alison Dowling; Ran Duan; Emma L. Duncan; C Farrar; Johanna Hadler; David Harvey; Tugce Karaderi; R Mogg; Emma Pomeroy; Karena Pryce; Jack A. Taylor; Laurie Savage; Panos Deloukas; Vasudev Kumanduri; Leena Peltonen; S. M. Ring; Pamela Whittaker
Faculty of Health; Institute of Health and Biomedical Innovation | 2009
N. J. Timpson; Jonathan H. Tobias; J. B. Richards; Nicole Soranzo; Emma L. Duncan; A. M. Sims; Pamela Whittaker; Vasudev Kumanduri; Guangju Zhai; Benjamin Glaser; John A. Eisman; Graeme Jones; Geoffrey C. Nicholson; Richard L. Prince; Ego Seeman; Tim D. Spector; Matthew A. Brown; Leena Peltonen; George Davey Smith; Panos Deloukas; David Evans
