A Martín Herrera

Proliferative fasciitis: ultrastructure and histogenesis.

The ultrastructure was studied of 2 cases of proliferative fasciitis (PF) which affected the fascia and subcutaneous fat. Two basic cell types were observed in the lesions: fibroblast‐like, and giant cells. The fibroblast‐like cells had myofibroblastic ultrastructural characteristics. The giant cells showed a well‐developed, rough endoplasmic reticulum, irregularly distributed filaments and clear lipid droplets in their cytoplasms. Ultrastructurally, the giant cells seemed to belong to a cellular line capable of synthesizing ground substances and extracellular fibers, but with a modified phenotype. A consistent feature was the presence of nodular aggregates of numerous proliferating perivascular cells. Transitional forms between perivascular, fibroblast‐like, and giant cells were observed. Our hypothesis is that perivascular cells (activated pericytes) are the source of the fibroblast‐like and giant cells in proliferative fasciitis.

Multiple verrucae vulgaris in a young woman's tattoo.

356 JEADV 2006, 20, 341–362

Clear cell sarcoma: a case mimicking primary cutaneous malignant melanoma.

Clear cell sarcoma (CCS) is a recently described variant of sarcoma characterized by prominent clear cells showing features similar to clear cell melanoma. This neoplasm was first described by Dr. Franz M. Erzinger. Primary CCS usually arises in deeper soft tissues, in association with fascia, tendons, or aponeuroses. Characteristic translocation t(12;22) (q13;q12) has been considered pathognomonic for CCS. Prognosis is related to tumor size. An early recognition and initial radical surgery is the key to a favourable outcome. We present a patient with an unusual neoplasm that resembled malignant melanoma.

Atypical molluscum contagiosum.

JEADV 2006, 20 , 461–488

Unilateral naevoid telangiectasia in a young man after chemotherapy: a simple coincidence or a new clinical association?

JEADV 2006, 20 , 999–1032

Infliximab‐induced eczematoid eruption

JEADV 2006, 20, 1133–1167

Reactive pseudotumoural papular mucinosis: a new clinicopathological presentation?

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