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Dive into the research topics where Abelardo P. Martinez is active.

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Featured researches published by Abelardo P. Martinez.


Journal of Theoretical Biology | 1962

Non-classical antimetabolites. V. Further factors in the design of exo-alkylating enzyme inhibitors, particularly of lactic dehydrogenase†

B. R. Baker; William W. Lee; Ethel Tong; Leonard O. Ross; Abelardo P. Martinez

Glutamic dehydrogenase and lactic dehydrogenase can still be reversibly inhibited by oxanilates and salicylates bearing bulky groups necessary for giving the hypothetically possible exo-alkylating type of irreversible inhibition. In addition, several new types of effective reversible inhibitors have been found such as the quinolone-carboxylic acids, coumarin-3-carboxylic acid, coumarilic acid and 1,3-indanedione.


Journal of Medicinal Chemistry | 1960

Potential Anticancer Agents --L. Non-Classical Antimetabolites--II. Some Factors in the Design of Exo-Alkylating Enzyme Inhibitors, partcularly of Lactic Dehydrogenase

B. R. Baker; William W. Lee; W. A. Skinner; Abelardo P. Martinez; Ethel Tong


Journal of Medicinal Chemistry | 1974

Folic acid antagonists. Methotrexate analogs containing spurious amino acids. Dichlorohomofolic acid.

William W. Lee; Abelardo P. Martinez; Leon Goodman


Journal of Organic Chemistry | 1976

Daunomycinone analogues via the Diels-Alder reaction. Synthesis and chemistry of some 6,11-dihydroxy-5,12-naphthacenediones

William W. Lee; Abelardo P. Martinez; Thomas H. Smith; David W. Henry


Journal of Organic Chemistry | 1965

An Improved Synthesis of Willardiine and 1-(2',2'-Diethoxyethyl)uracil1

Abelardo P. Martinez; William W. Lee


Archive | 1980

Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells

William W. Lee; J. Martin Brown; Abelardo P. Martinez; Michael Cory


Journal of Organic Chemistry | 1972

Guanine, thioguanine, and related nucleosides by the mercuric cyanide--silyl method. An improved synthesis of -2'-deoxythioguanosine.

William W. Lee; Abelardo P. Martinez; Leon Goodman; David W. Henry


Archive | 1989

Process for preparing 1,2,4-benzotriazine oxides

William W. Lee; J. Martin Brown; Edward W. Grange; Abelardo P. Martinez; Michael Tracy; Daniel J. Pollart


Journal of Organic Chemistry | 1962

Potential Anticancer Agents. LXXVIII.1Nonclassical Antimetabolites. IV.2Synthesis of Compounds Related to 4-(Iodoacetamido)salicylic Acid, an Exo-Alkylating Irreversible Inhibitor

B. R. Baker; William W. Lee; Abelardo P. Martinez; Leonard O. Ross; Leon Goodman


Journal of Organic Chemistry | 1969

Structure and properties of some D-arabino- and D-xylopyranosyladenines

Abelardo P. Martinez; William W. Lee; Leon Goodman

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