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Leonard O. Ross

SRI International

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Journal of Theoretical Biology | 1962

Non-classical antimetabolites. V. Further factors in the design of exo-alkylating enzyme inhibitors, particularly of lactic dehydrogenase†

B. R. Baker; William W. Lee; Ethel Tong; Leonard O. Ross; Abelardo P. Martinez

Glutamic dehydrogenase and lactic dehydrogenase can still be reversibly inhibited by oxanilates and salicylates bearing bulky groups necessary for giving the hypothetically possible exo-alkylating type of irreversible inhibition. In addition, several new types of effective reversible inhibitors have been found such as the quinolone-carboxylic acids, coumarin-3-carboxylic acid, coumarilic acid and 1,3-indanedione.

Journal of the American Chemical Society | 1961

POTENTIAL ANTICANCER AGENTS.1 LXVI. NON-CLASSICAL ANTIMETABOLITES. III.2 4-(IODOACETAMIDO)-SALICYLIC ACID, AN EXO-ALKYLATING IRREVERSIBLE INHIBITOR OF GLUTAMIC DEHYDROGENASE

B. R. Baker; William W. Lee; Ethel Tong; Leonard O. Ross

Journal of Organic Chemistry | 1962

Potential Anticancer Agents. LXXVIII.1Nonclassical Antimetabolites. IV.2Synthesis of Compounds Related to 4-(Iodoacetamido)salicylic Acid, an Exo-Alkylating Irreversible Inhibitor

B. R. Baker; William W. Lee; Abelardo P. Martinez; Leonard O. Ross; Leon Goodman

Journal of Chemical & Engineering Data | 1971

Improved syntheses of ethyl 3,3,3-trifluoropropionate and 3,3,3-trifluoropropionic acid

Howard M. Peters; Leonard O. Ross; Robert L. Simon; Marion E. Hill

Journal of Organic Chemistry | 1967

Reduction of difluoronitroacetates esters. The preparation and properties of 2,2,2-difluoronitroethanol and the novel formation of hemiacetals by reduction

Marion E. Hill; Leonard O. Ross

Journal of Medicinal Chemistry | 1963

Synthesis of Mustards from Putrescine, Cadaverine, and 1,3-Diaminopropane1

William W. Lee; Bernard J. Berridge; Leonard O. Ross; Leon Goodman

Journal of Organic Chemistry | 1958

Potential Anticancer Agents.1XII. The Reaction of Chloroacetonitrile with L-Cysteine, DL-Homocysteine, and Cysteamine

Leon Goodman; Leonard O. Ross; B. R. Baker

Journal of Chemical & Engineering Data | 1975

Synthesis of gem-dinitroethyl trifluoromethyl ethers with sulfur tetrafluoride

Howard M. Peters; Robert L. Simon; Leonard O. Ross; Donald L. Ross; Marion E. Hill

Journal of Organic Chemistry | 1961

Notes- Potential Anticancer Agents. LVI. Synthesis of 5-[Bis(2-chloroethyl)aminomethyl]uracil

Leonard O. Ross; William W. Lee; M Schelstraete; Leon Goodman; B. R. Baker

Journal of Organic Chemistry | 1961

Potential Anticancer Agents.1LIII. Alkylating Agents Derived from Some Folic Reductase Inhibitors

Joseph I. DeGraw; Leonard O. Ross; Leon Goodman; B. R. Baker

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Marion E. Hill

SRI International

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B. R. Baker

SRI International

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Howard M. Peters

Stanford University

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Leon Goodman

SRI International

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William W. Lee

SRI International

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Donald L. Ross

SRI International

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Abelardo P. Martinez

SRI International

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Ethel Tong

SRI International

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Clifford L. Coon

SRI International

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