Adolf Hubele

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Pesticide Chemistry: Human Welfare and Environment#R##N#Synthesis and Structure-Activity Relationships | 1983

Adolf Hubele; Walter Kunz; Wolfgang Eckhardt; Elmar Sturm

Abstract Out of the vast number of acyl anilines, generally known as herbicides until 1973, we found certain representatives, the acylalanines, with high fungicidal activity against Oomycetes, especially of the order Peronosporales. Two commercial products have been developed so far. The biological activities depend on substitution patterns in the acyl, aryl, and alkyl moiety of the acylalanine molecule. Structure-activity correlations using Hansch equations have been established. Acylalanines are racemates which have been resolved into their optical antipodes. The dependence of biological activity upon the optical configuration has been studied.

Archive | 1988