Adrienn Hegedüs

A simple synthesis of 2-substituted oxazolines and oxazines

Abstract β-Aminoalcohols react with carboxylic acids in the presence of a zeolite, Ersorb-4, resulting in the formation of oxazoline derivatives in good yields. Similarly, 3-aminopropanol and benzoic acid gave the corresponding 2-phenyloxazine.

Convenient one-pot heterogeneous catalytic method for the preparation of 3,4 -dihydropyrimidin -2 (1H) -ones

Abstract A new, simple, environmentally friendly synthesis of dihydropyrimidinones from aromatic and aliphatic aldehydes, ethyl acetoacetate, and urea or thiourea using a small‐pore‐size zeolite as catalyst is described. Compared with the classical Biginelli reaction conditions, this method has the advantage of high yield, shorter reaction time, and recyclable and reusable catalyst.

Zeolite-catalyzed simple synthesis of isochromans via the oxa-Pictet–Spengler reaction

The modified small pore size zeolite E4a has been found to be an efficient catalyst for the synthesis of isochromans via the oxa-Pictet–Spengler reaction. This method is simple, cheap, environmentally-friendly and gives the isochromans in high yield.

Microwave-assisted conversion of oximes into nitriles in the presence of a zeolite

Aromatic aldoximes were converted to the corresponding nitriles in a microwave oven in the presence of a molecular sieve-type modified zeolite, Ersorb, under solvent-free conditions. The yields depended on the substituent of the oxime.

Zeolite-catalyzed environmentally friendly synthesis of benzimidazole derivatives

Abstract A simple and environmentally friendly synthesis of substituted benzimidazoles was developed using a small‐pore‐size zeolite. The similar reaction was not applicable to the preparation of 2‐substituted imidazolines.

Zeolite-catalyzed environmentally friendly tetrahydropyranylation of alcohols and phenols

Abstract A simple and environmentally friendly tetrahydropyranylation of various alcohols and phenols at room temperature was elaborated by using a small pore size zeolite. The material is also suitable for the deprotection but with less efficiency.