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Dive into the research topics where Aglécio Luiz de Souza is active.

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Featured researches published by Aglécio Luiz de Souza.


Annals of the New York Academy of Sciences | 2008

Salivary Cortisol Levels in Brazilian Citizens of Distinct Socioeconomic and Cultural Levels

Márcia C. Garcia; Aglécio Luiz de Souza; Geruza P. Bella; Dora Maria Grassi-Kassisse; Artur P. Tacla; Regina Celia Spadari-Bratfisch

We have analyzed the perceived stress index, the basal salivary cortisol levels, and the awakening cortisol response (ACR) in 86 volunteers of low (LSES) and high socioeconomic status (HSES). The LSES presented higher perceived stress index and basal salivary cortisol levels, nonaltered ACR, or cortisol diurnal rhythm. We have concluded that the LSES is associated with high perceived stress index and salivary cortisol levels, which could impact negatively in health, and that it is related to the daily life stress experienced by individuals in the LSES group. Because the LSES corresponds to about 30% of the total Brazilian population, this conclusion might have a great impact on public health policies and costs.


Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2015

Evaluation of patients with head and neck cancer performing standard treatment in relation to body composition, resting metabolic rate, and inflammatory cytokines

Thalyta Morandi Ridolfi de Carvalho; Daniela Miguel Marin; Conceição Aparecida da Silva; Aglécio Luiz de Souza; Maristela Talamoni; Carmen Silvia Passos Lima; Sarah Monte Alegre

Squamous cell carcinoma of the head and neck (SCCHN) usually emerges as a set of signs and symptoms that, either alone or in combination with standard treatment, may lead to malnutrition and weight loss.


Journal of Diabetes and Its Complications | 2017

Assessment of insulin sensitivity by the hyperinsulinemic euglycemic clamp: Comparison with the spectral analysis of photoplethysmography.

Aglécio Luiz de Souza; Gisele Almeida Batista; Sarah Monte Alegre

AIMS We compare spectral analysis of photoplethysmography (PTG) with insulin resistance measured by the hyperinsulinemic euglycemic clamp (HEC) technique. MATERIAL AND METHOD A total of 100 nondiabetic subjects, 43 men and 57 women aged 20-63years, 30 lean, 42 overweight and 28 obese were enrolled in the study. These patients underwent an examination with HEC, and an examination with the PTG spectral analysis and calculation of the PTG Total Power (PTG-TP). Receiver-operating characteristic (ROC) curves were constructed to determine the specificity and sensitivity of PTG-TP in the assessment of insulin resistance. RESULTS There is a moderate correlation between insulin sensitivity (M-value) and PTG-TP (r=- 0.64, p<0.0001). The ROC curves showed that the most relevant cutoff to the whole study group was a PTG-TP>406.2. This cut-off had a sensitivity=95.7%, specificity =84,4% and the area under the ROC curve (AUC)=0.929 for identifying insulin resistance. All AUC ROC curve analysis were significant (p<0.0001). CONCLUSION The use of the PTG-TP marker measured from the PTG spectral analysis is a useful tool in screening and follow up of IR, especially in large-scale studies.


Respiratory Medicine | 2018

Influence of weight loss on pulmonary function and levels of adipokines among asthmatic individuals with obesity: One-year follow-up

Letícia Baltieri; Everton Cazzo; Aglécio Luiz de Souza; Sarah Monte Alegre; Rodolfo de Paula Vieira; Edson Antunes; Gláucia C. Mello; Luiz Cláudio Martins; Elinton Adami Chaim

BACKGROUND Individuals with obesity are more likely to develop asthma, but the exact mechanism is still uncertain and several hypotheses have been raised, such as the release of inflammatory mediators secreted by adipose tissue. OBJECTIVE To assess the effects of weight loss in patients submitted to bariatric surgery on pulmonary and systemic inflammation. METHOD The study evaluated patients undergoing bariatric surgery (Roux-en-Y gastric bypass) with the diagnosis of asthma, except smokers. The patients were evaluated at the time of entry into a preoperative weight loss group (T1), just before bariatric surgery (T2), six months after surgery (T3), and 12 months after surgery (T4). The following were measured: anthropometric data, dosage of systemic inflammatory markers by means of blood collection, pulmonary inflammatory markers obtained by induced sputum collection, pulmonary function parameters, and asthma activity assessed by a Asthma Control Test (ACT) questionnaire. RESULTS Nineteen patients participated in the study. There were significant reductions in the systemic levels of interleukin (IL)-8 (p = 0.002), C-reactive protein (CRP) (p = 0.003), leptin (p = 0.001) and tumor necrosis factor (TNF)-α (p = 0.007), and significant increase in the systemic levels of IL-6 (p = 0.004) over time and adiponectin in T2 (p = 0.025). In regards to pulmonary inflammation, there were significant reductions in the sputum levels of TNF-α (p < 0.001). There was no significant improvement of the pulmonary function parameters (p > 0.05) and significant improvement in asthma activity scores (p < 0.0001). CONCLUSION Weight loss was associated with significant changes in the systemic and pulmonary inflammatory profiles of individuals with asthma, leading to a better asthma control as a result of an increase in some anti-inflammatory mediators and a reduction of pro-inflammatory mediators.


Contraception | 2018

Hyperinsulinemic-euglycemic clamp over the first year of use of depot-medroxyprogesterone acetate as a contraceptive

Vaneska Melhado-Kimura; Gisele Almeida Batista; Aglécio Luiz de Souza; Priscilla de Nazaré Silva dos Santos; Sarah Monte Alegre; Elizabeth João Pavin; Luis Bahamondes; Arlete Maria dos Santos Fernandes

OBJECTIVE The literature lacks data on the use of the gold-standard hyperinsulinemic-euglycemic clamp (HEC) technique for the evaluation of insulin resistance (IR) in depot-medroxyprogesterone acetate (DMPA) users. This study assessed carbohydrate metabolism in non-obese users of DMPA using the HEC technique. STUDY DESIGN A prospective, non-randomized, comparative study conducted at the Family Planning Clinic/Metabolic Unit, University of Campinas, Brazil. Forty-eight women aged 18-39 years underwent HEC: 30 initiating use of DMPA and 18 initiating use of a copper intrauterine device (IUD). Data from 15 women in each group, who completed the follow-up and underwent HEC at12 months, were compared using repeated measures ANOVA. All women were advised to perform aerobic physical exercise for 150 min/week; body composition and total energy intake were evaluated. Main outcome measures were IR defined by M-value <4 mg/kg/min, and blood levels of insulin. Additional outcomes were total cholesterol, HDL-cholesterol, triglycerides, LDL-cholesterol, adipokines and free fatty acids. RESULTS At 12 months, two women in the DMPA group and none in the IUD group had developed IR. The groups were similar in in M-values and in blood levels of insulin, total cholesterol, HDL-cholesterol, LDL-cholesterol, adipokines or free fatty acids. Triglyceride levels increased in the DMPA group when compared to the IUD group, 80.0 (SD 47.8) versus 61.8 (SD 35.8) mg/dL respectively, (p=.033); and increased the total daily energy intake, 1828.3 (SD 518.9) versus 1300.8 (SD 403.4) kilocalories/24hs, respectively in the same groups, (p=.041). All the DMPA users showing higher insulin sensitivity at 12 months reported performing physical activity regularly. CONCLUSIONS Changes occurred in carbohydrate metabolism in DMPA users in the first year of use of the method. It is possible that the regular aerobic exercise may exert a beneficial and protective effect against the factors that trigger these changes. IMPLICATIONS STATEMENT Carbohydrate metabolism undergoes adverse changes in few young non-obese women during the first year of DMPA use and regular aerobic exercise may exert a beneficial and protective effect against these changes.


Archives of Endocrinology and Metabolism | 2017

Body composition, resting energy expenditure and inflammatory markers: impact in users of depot medroxyprogesterone acetate after 12 months follow-up.

Gisele Almeida Batista; Aglécio Luiz de Souza; Daniela Miguel Marin; Marina Sider; Vaneska de Carvalho Melhado; Arlete Maria dos Santos Fernandes; Sarah Monte Alegre

Objective The aim of this study was to evaluate for 12 months the changes of body weight using Depot Medroxyprogesterone Acetate (DMPA) and if these changes are related to inflammatory markers. Subjects and methods Twenty women of childbearing age who chose the DMPA, without previous use of this method, BMI < 30 kg/m2, and 17 women using IUD TCu 380A, participated in the study. At the baseline and after one year, changes in weight gain, body composition by the bioimpedance electric method, resting energy expenditure (REE) by the indirect calorimetry method, inflammatory markers and HOMA-IR were assessed. Results After 12 months of evaluation, we could observe a significant increase in the DMPA group in weight (3,01 kg) and BMI, while the IUD groups only significant increase was observed in the BMI. Relative to REE there was an increase of basal metabolic rate (BMR) in both groups after one year. The sub-group DMPA that gained < 3 kg had increased significant weight, BMI and body surface (BS) with respiratory quotient (RQ) reduction, while the sub-group that gained ≥ 3 kg had a significant increase in weight, BMI, BS, fat-free mass, fat mass, BMR, Leptin, HOMA-IR and waist circumference, with RQ significantly reduced. Conclusion Our study found significant changes in weight, body composition and metabolic profile of the population studied in the first 12 months of contraceptive use. These changes mainly increased body weight, leptin levels and HOMA-IR which can contribute to the development of some chronic complications, including obesity, insulin resistance and diabetes mellitus.


Obesity Surgery | 2009

GLP-1 and Adiponectin: Effect of Weight Loss After Dietary Restriction and Gastric Bypass in Morbidly Obese Patients with Normal and Abnormal Glucose Metabolism

Camila Puzzi de Carvalho; Daniela Miguel Marin; Aglécio Luiz de Souza; José Carlos Pareja; Elintom Adami Chaim; Sílvia de Barros Mazon; Conceição Aparecida da Silva; Bruno Geloneze; E. Muscelli; Sarah Monte Alegre


Obesity Research | 2003

Insulin resistance in nondiabetic morbidly obese patients: effect of bariatric surgery.

Juliano Alves Pereira; Mary Aparecida Carvalho Tavares Lazarin; José Carlos Pareja; Aglécio Luiz de Souza; E. Muscelli


Revista Da Escola De Enfermagem Da Usp | 2013

Stress among nurses: an examination of salivary cortisol levels on work and day off

Maria Cecília Pires da Rocha; Milva Maria Figueiredo De Martino; Dora Maria Grassi-Kassisse; Aglécio Luiz de Souza


Revista Da Escola De Enfermagem Da Usp | 2013

Estresse em enfermeiros: o uso do cortisol salivar no dia de trabalho e de folga

Maria Cecília Pires da Rocha; Milva Maria Figueiredo De Martino; Dora Maria Grassi-Kassisse; Aglécio Luiz de Souza

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Sarah Monte Alegre

State University of Campinas

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Filipy Borghi

State University of Campinas

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Daniela Miguel Marin

State University of Campinas

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Érica A. M. Camargo

State University of Campinas

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