Dora Maria Grassi Kassisse

Uroanalysis of Wistar, Wistar Kyoto and Spontaneous Hypertensive Rats

Uroanalysis reveals information about metabolic, hepatic, and renal function as well as indications of the dysfunction etiology. It is a simple, practical and quick method to perform analysis of the biochemical urine constituents by markers in reagent strips. In this study, we evaluated the urine of Wistar, Wistar Kyoto (WKY) and spontaneously hypertensive rats (SHR). Uroanalysis of WKY and SHR rats indicated ketosis and increased protein presence than Wistar. The WKY and SHR urine was more diluted than Wistar. Only the WKY presented haemolysis. The results indicate absence of hepatic dysfunction and infections in the urine of the different strains of rats. Ketonuria corroborates with the fasting rat’s state, hematuria is an indicative of the urinary system dysfunction and proteinuria specifically refers to renal dysfunction, these are related to high WKY weight and SHR hypertension. Dilution of urine may be related to hydroelectrolytic imbalance due to changes in the HPA axis presented by WKY and SHR.

Relationship between psychosocial stress, resilience, sleep quality and somnolence in undergraduate pharmacy students

Psychosocial stress, poor quality of sleep and lack of resilience are some of the biggest challenges society have to face nowadays and it is no different for undergraduated students. Those factors can affect their academic performance, health and also their life outside the university. We aimed to correlate the effects of acute psychosocial stress, and its implications on sleep quality, resilience and somnolence in undergraduate pharmacy students.

STUDY OF THE ACUTE AND CHRONIC EFFECTS OF MANUAL THERAPY ON THE SALIVARY MELATONIN CONCENTRATION IN STUDENTS PREPARING TO APPLY FOR THE UNIVERSITIES

Isabela V. Vieira (IC), Heloísa Ap. Ferreira (PQ), Aglécio Luiz de Souza (PQ), Fernando Canova (PQ). Dora M. Grassi-Kassisse (PQ). Abstract The entrance exam is a stressful experience for students. The manual therapy (MT) act as an strategy to confront the stressor agent (coping). To evaluate the effects of MT we analyzed the salivary concentration of melatonin, a counter regulatory hormone of stress, produced by the pineal gland.

Analysis of acute and chronic stress by quantification of cortisol in saliva and hair, BDNF in saliva and analysis of Val66Met the BDNF polymorphism in graduating: announcement of a pilot study

Cortisol is considered as the stress hormone. BDNF is involved in plasticity, including memory, learning and sleep. The hair cortisol assess chronic stress. Our goals are the standardization of cortisol quantification techniques in hair (chronic), BDNF in saliva and the polymorphism identification in this population.

APPLICATION OF THEORY IN PRACTICE: INTEGRATING AREAS - exact and biological- IN GRADUATE - Study of ECC in hypertensive rats.

Bruna Sabrina Hergert (IC), Ana Gabriela Conceição-Vertamatti (PQ), Larissa Yuri Ishizu (PQ), Luiz Alberto Ramos (PQ), Gustavo Trevisan Costa (IC), Fernando Canova (PQ). Laura Leticia Ramos Rifo (PQ), Dora M. Grassi-Kassisse (PQ). Abstract Exact and Biological sciences are areas of expertise that complement each other. The associations between these areas are little explored in the formation of graduate student. Proposals to recruit students of exact for help with the analysis of the data obtained in Labeest generated great interest of applicants’ scholarship BAS-SAE. Data analysis electrocardiography of models of hypertension in rats was carried out by a student of statistics, which can apply their knowledge acquired during their training.