Ahmet Çetin

3-(2-Hydro­xy­phenyl)-4-phenyl-1H-1,2,4-triazole-5(4H)-thione

The title molxadecule, C14H11N3OS, is non-planar. The phenyl and hydroxyxadphenyl rings form dihedral angles of 69.08u2005(9) and 24.57u2005(9)°, respectively, with the five-membered 2,4-dixadhydro-1,2,4-triazole ring. The molxadecules form centrosymmetric dimers through N—H⋯S hydrogen bonds, with an N⋯S distance of 3.279u2005(2)u2005A. In addition, the molxadecule contains one O—H⋯N and one C—H⋯π(phenyl) intramolecular interactions. The dimers are connected through weak intermolecular C—H⋯π(hydroxyxadphenyl) interactions into chains in the a direction.

4‐Ethyl‐5‐(2‐hydroxy­phenyl)‐2H‐1,2,4‐triazole‐3(4H)‐thione

In the title compound, C10H11N3OS, an intramolecular C—H⋯S hydrogen bond is observed, which leads to a thione tautomer in the solid state. The benzene ring forms a dihedral angle of 85.33u2005(6)° with the triazole ring. There are intermolecular N—H⋯S and O—H⋯N hydrogen bonds and C—H⋯π interactions.

N-Cyclohexyl-2-[5-(4-pyridyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-ylsulfanyl]-acetamide dihydrate

In the title compound, C22H25N5OS.2H2O, the molecules are stacked in columns running along the b axis. In this arrangemant, the molecules are linked to each other by a combination of one two-centre N-H...O hydrogen bond and four two-centre O-H...O hydrogen bonds containing two types of ring motif, viz. R(4)4(10) and R(3)3(11). In the crystal structure, centrosymmetric pi-pi interactions between the triazole rings, with a distance of 3.691 (2) A between the ring centroids, also affect the packing of the molecules.

Synthesis of (1R,2R)-1,2-bis-(5-(4-hydroxynaphthalen-1-ylazo)-[1,3,4]thiadiazol-2-yl)-ethane-1,2-diol

In this study, (1R,2R)-1,2-bis-(5-amino-1,3,4-thiadiazol-2-yl)ethane-1,2-diol (2), was synthesized by using (2R,3R)-(+)-Tartaric acid (1) as starting compound. Then the diazo component 3 was obtained from 2 and 1-naphthol. In addition, the structures of the synthesized compounds 2 and 3 were confirmed by elemental analyses, IR, 1H-NMR, and 13C-NMR spectra.

5-(Furan-2-yl)-4-(p-tolyl)-2,4-di­hydro-1,2,4-triazole-3-thione

In the title molxadecule, C13H11N3OS, the triazole plane forms dihedral angles of 3.8u2005(2) and 81.3u2005(2)° with the furan and p-tolyl ring planes, respectively. In the crystal structure, the molxadecules exist as centrosymmetric N—H⋯S hydrogen-bonded dimers, with an N⋯S distance of 3.312u2005(2)u2005A. The packing is further stabilized by C—H⋯O, C—H⋯N, C—H⋯π and π–π interactions.

5-(2-Hydro­xy­phenyl)-4-(p-tolyl)-2,4-di­hydro-1,2,4-triazole-3-thione

In the structure of the title compound, C15H13N3OS, the molxadecules form centrosymmetric dimers through strong N—H⋯S hydrogen bonds, with an N⋯S distance of 3.271u2005(3)u2005A. In addition, the molxadecule contains one O—H⋯N intramolecular hydrogen bond. The dimers are connected through weak intermolecular C—H⋯S hydrogen bonds into chains in the c direction, with a C⋯S distance of 3.742u2005(3)u2005A.

4‐Amino‐5‐(2‐hydroxy­phen­yl)‐2H‐1,2,4‐triazole‐3(4H)‐thione

In the title compound, C8H8N4OS, the planar triazole ring is effectively coplanar with the benzene ring, which facilitates the formation of three intraxadmolecular interxadactions N—H⋯S (leading to a thione tautomer in the solid state), O—H⋯N and C—H⋯N. Interxadmolecular N—H⋯S interxadactions lead to the formation of dimers, which are, in turn, linked to each other by N—H⋯O hydrogen bonds.

4-Benzyl-3-(2-hydroxy­phenyl)-1H-1,2,4-triazole-5(4H)-thione

In the title molxadecule, C15H13N3OS, the triazole ring plane forms dihedral angles of 18.99u2005(7) and 89.35u2005(7)° with the hydroxyxadphenyl and benzyl substituent ring planes, respectively. In the crystal structure, the molxadecules exist as centrosymmetric N—H⋯S hydrogen-bonded dimers, with an N⋯S distance of 3.287u2005(2)u2005A.

Accelerated synthesis of novel 1,2,4-triazolo[3,4-b][1,3,4]-thiadiazepines under microwave irradiation

A convenient and efficient one step, base catalyzed synthesis of 3,5-disubstituted-4-amino-1,2,4-triazoles by condensation of thiol and hydrazide is presented. An environmentally benign and economic synthesis for the title compounds is described from readily accessible substituted 4-amino-5-mercapto-1,2,4-triazoles and substituted chalcones on basic alumina that are accelerated by exposure to microwave irradiation.

5,5′-Pyridine-2,6-diylbis[4-ethyl-2,4-dihydro-1,2,4-triazole-3(2H)-thione]

In the title compound, C13H15N7S2, the two triazole rings are twisted away from the central pyridine ring by 11.7u2005(2) and 41.8u2005(1)°. Inversion-related molxadecules are linked by N—H⋯S hydrogen bonds, forming dimers which are linked into a chain by N—H⋯N hydrogen bonds.