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Featured researches published by Ahmet R. Oğuz.


Biological Trace Element Research | 2014

Metal Levels in the Liver, Muscle, Gill, Intestine, and Gonad of Lake Van Fish (Chalcalburnus tarichi) with Abnormal Gonad

Ahmet R. Oğuz; Aslı Çilingir Yeltekin

Recently, an increasing number of studies have shown that Lake Van—the biggest soda lake in the world—is polluted due to an increasing population. Studies have shown abnormalities in the Lake Van fish (Chalcalburnus tarichi), the sole fish species that inhabits the lake. Unlike the vitellogenic and mature oocytes in normal gonads, abnormal gonads show large amounts of connective tissue and young oocytes. In this study, metal levels (nickel [Ni], copper [Cu], cobalt [Co], iron [Fe], zinc [Zn], cadmium [Cd], lead [Pb], and manganese [Mn]) in the muscle, liver, gill, intestine, and gonad of Lake Van fish with normal and abnormal gonads were assessed. Further, the metal contents in the wastewater from the wastewater treatment facility situated near Lake Van in Van City were assessed. All the metal levels, except that of Zn, were high in the Lake Van environment (P < 0.05). The highest metal content in the tissues was for Fe, while the lowest level was for Co. The Pb level was found to be very high in both fish groups. Cd was not found in the tissues of both fish groups. The levels of Fe, Cu, Pb, and Mn were not significant in the tissues of both normal and abnormal fish groups. Zn level was significantly high in the livers and gonads of fish with abnormal gonads, and Co level was significantly high only in the livers (P < 0.05). Consequently, high levels of Zn in the liver and gonads and high levels of Co in the liver may be factors causing the abnormal gonads in the Lake Van fish.


Süleyman Demirel Üniversitesi Eğirdir Su Ürünleri Fakültesi Dergisi | 2018

Van Balığı’nın (Alburnus tarichi, Güldenstädt 1814) Yaş Değişkenine Bağlı Olarak Farklı Dokularındaki Bazı Metal Düzeylerinin İncelenmesi

Aslı Çilingir Yeltekin; Ahmet R. Oğuz; Fadime İribuğday; Burcu Ergöz

Cevresel kirlenme sonucu meydana gelen kirlilik, her gecen gun ekosistemi ve insanlari daha fazla tehdit etmektedir bu durum Van Golu icinde gecerlidir. Bu amacla Van Baliginin (A lburnus tarichi , Guldenstadt 1814) farkli yaslara gore bazi metal duzeylerinin degisimi arastirildi. Calismada alinan Van Baliklarinin kas, karaciger, solungac, bobrek, bagirsak, gonad ve beyin dokularinda berilyum(Be), bizmunt (Bi), kursun (Pb), kadminyum (Cd), demir (Fe), bakir (Cu), cinko (Zn), selenyum (Se), nikel (Ni), mangan (Mn), Kobalt (Co), krom (Cr), lityum (Li), kalsiyum (Ca), magnezyum (Mg), sodyum (Na) ve potasyum (K) elementleri inductively-coupled plasma-optic emission spectroscopy (ICP-OES) ile analiz edildi. Sonuclar toksik elementler, eser elementler ve makro elementler olarak degerlendirildi. Oldukca toksik olan Be, Bi, Pb ve Cd elementleri Van baligi dokularinda tespit edildi. Ozellikle de beyin dokusunda konsantrasyonlarin daha yuksek oldugu gozlendi. Ni metalinin beyin dokusu konsantrasyonun diger dokulara oranla daha yuksek oldugu tespit edilmistir. Calismaya genel olarak bakildiginda, 3 yas ve 4 yas gruplarinin metal konsantrasyon degerleri arasinda fark gozlenmezken 5 yas grubunun degerlerinin farkli oldugu tespit edilmistir ( P <0.05).


Chemistry and Ecology | 2018

Oxidative and genotoxic effects of bisphenol A on primary gill cell culture of Lake Van Fish (Alburnus tarichi Güldenstädt, 1814)

Elif Kaval Oğuz; Okan Arihan; Ahmet R. Oğuz

ABSTRACT Lake Van is the largest lake in Turkey. The lake limits lifespan due to its high pH and brackish water. For this reason, only a single species of fish (Van Fish) is living in the lake that has been adapted to these conditions. In the present study, we investigated the total oxidant status (TOS), total antioxidant status (TAS), malondialdehyde (MDA) level and DNA damage effect of bisphenol A (BPA) (10−7, 10−6 and 10−5 M) on primary gill cell culture of Van Fish for 24 and 48 h of incubation periods. TAS levels were not changed when compared to those of the control group, but TOS levels were decreased in both 24 and 48 h. The MDA level increased only at the highest concentration (10−5) at the end of 12 and 24 h (p < .05). DNA damage increased only at the 10−5 M concentration after 48 h. At the end of the experiment, BPA exposure caused lipid peroxidation and genotoxic effect. These results indicate that high levels of BPA exposure induced oxidative stress and DNA damage by time- and concentration-dependent fashion in the gill cell culture of Van Fish. Gill cell culture is a useful model for the rapid identification of the harmful effects of chemicals in the aquatic environment.


Somatosensory and Motor Research | 2017

Neuromuscular degenerative effects of Ankaferd Blood Stopper® in mouse sciatic nerve model

Ramazan Üstün; Elif Kaval Oğuz; Çağrı Delilbaşı; Ayşe Şeker; Filiz Taşpınar; Mehmet Resit Oncu; Ahmet R. Oğuz

Abstract Purpose: Ankaferd Blood Stopper® (ABS), a licenced medicinal herbal extract, is commonly used as an effective topical haemostatic agent. This study is designed to investigate whether topical ABS application may cause peripheral nerve degeneration and neuromuscular dysfunction in a mouse sciatic nerve model. Methods: Twenty mice were randomly divided into two groups; an ABS treated experimental group and a saline-treated control group. Left sciatic nerves were treated with 0.3 ml of ABS in the experimental group and 0.3 ml of sterile saline in the control group for 5 min. Peripheral nerve degeneration and neuromuscular dysfunction were evaluated by behavioural tests, electrophysiological analysis and weight ratio comparison of target muscles. Results: The motor function, assessed by the sciatic function index, was significantly impaired in ABS-treated animals as compared to the animals treated with saline. Motor coordination, evaluated with the rotarod test, was significantly decreased (–42%) in ABS-treated animals compared to the saline-treated animals. The degree of pain, assessed by the reaction latency to thermal stimuli (hot-plate test), was significantly prolonged (313%) in ABS-treated mice when compared to the saline-treated mice. ABS-treated mice showed a significant reduction in motor nerve conduction velocity (MNCV) (–52%) and the compound muscle action potential (CMAP) (–47%); however, it significantly prolonged onset latency (23%). The gastrocnemius muscles weight ratio of the ABS group was considerably lower than that of the control group. Conclusions: These findings demonstrate that ABS triggers peripheral nerve degeneration and functional impairment and, thus promotes a deterioration of sciatic nerves.


Fish Physiology and Biochemistry | 2007

Gonadal histology and some biochemical characteristics of Chalcalburnus tarichi (Pallas, 1811) having abnormal gonads

Güler Ünal; V. Türkoğlu; Ahmet R. Oğuz; Burak Kaptaner


Bulletin of Environmental Contamination and Toxicology | 2013

Determination of Selected Endocrine Disrupting Chemicals in Lake Van, Turkey

Ahmet R. Oğuz; Ertuğrul Kankaya


The Journal of Membrane Biology | 2013

Environmental Regulation of Mitochondria-Rich Cells in Chalcalburnus tarichi (Pallas, 1811) During Reproductive Migration

Ahmet R. Oğuz


Fish Physiology and Biochemistry | 2008

Determination of hormones inducing oocyte maturation in Chalcalburnus tarichi (Pallas, 1811)

Güler Ünal; E. Erdoğan; Ahmet R. Oğuz; Burak Kaptaner; Ertuğrul Kankaya; M. Elp


Bulletin of Environmental Contamination and Toxicology | 2015

Vitellogenin in the Male Lake Van Fish (Chalcalburnus tarichi Pallas, 1811)

Ahmet R. Oğuz; Burak Kaptaner; Güler Ünal


Fish Physiology and Biochemistry | 2018

Development of osmoregulatory tissues in the Lake van fish (Alburnus tarichi) during larval development

Ahmet R. Oğuz

Collaboration


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Güler Ünal

Yüzüncü Yıl University

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Burak Kaptaner

Yüzüncü Yıl University

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Elif Kaval Oğuz

Yüzüncü Yıl University

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Ertuğrul Kankaya

Yüzüncü Yıl University

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Ayşe Şeker

Yüzüncü Yıl University

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E. Erdoğan

Yüzüncü Yıl University

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Filiz Taşpınar

Yüzüncü Yıl University

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M. Elp

Yüzüncü Yıl University

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Mehmet Resit Oncu

Yüzüncü Yıl University

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