Akio Kayano

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Featured researches published by Akio Kayano.

Organic Letters | 2015

Kazato Inanaga; Takashi Fukuyama; Manabu Kubota; Yuki Komatsu; Hiroyuki Chiba; Akio Kayano; Katsuya Tagami

A novel and efficient method for the Cr(II)-mediated desulfonylation of α-sulfonyl ketone by a Cr-ligand-Mn system has been developed during the course of process research on Halaven (eribulin mesylate). This reaction is dramatically accelerated in the presence of an appropriate bipyridyl-type ligand. This system is applicable to reduction of α-sulfur-substituted ketones. In addition, a Cr-Cp2ZrCl2-Mn catalytic system is also applicable to desulfonylation of α-sulfonyl ketone.

Synlett | 2013

Brian Austad; Trevor L. Calkins; Charles E. Chase; Francis G. Fang; Thomas E. Horstmann; Yongbo Hu; Bryan M. Lewis; Xiang Niu; Thomas A. Noland; John D. Orr; Matthew J. Schnaderbeck; Huiming Zhang; Naoki Asakawa; Naoki Asai; Hiroyuki Chiba; Takashi Hasebe; Yorihisa Hoshino; Hiroyuki Ishizuka; Takashi Kajima; Akio Kayano; Yuki Komatsu; Manabu Kubota; Hirofumi Kuroda; Mamoru Miyazawa; Katsuya Tagami; Tomohiro Watanabe

Archive | 2005

Akio Kayano; Katsutoshi Nishiura

Archive | 1998

Katsuya Tagami; Nobuo Niikawa; Akio Kayano; Hirofumi Kuroda

Synlett | 2013

Brian Austad; Farid Benayoud; Trevor L. Calkins; Silvio Campagna; Charles E. Chase; Hyeong-wook Choi; William J. Christ; Robert Costanzo; James Cutter; Atsushi Endo; Francis G. Fang; Yongbo Hu; Bryan M. Lewis; Michael D. Lewis; Shawn McKenna; Thomas A. Noland; John D. Orr; Marc Pesant; Matthew J. Schnaderbeck; Gordon D. Wilkie; Taichi Abe; Naoki Asai; Yumi Asai; Akio Kayano; Yuichi Kimoto; Yuki Komatsu; Manabu Kubota; Hirofumi Kuroda; Masanori Mizuno; Taiju Nakamura

Organic Process Research & Development | 2016