Akitoshi Fujiya

Molecular Iodine Catalyzed Cross-Dehydrogenative Coupling Reaction between Two sp3 C–H Bonds Using Hydrogen Peroxide

A useful method for molecular iodine catalyzed oxidative C-C bond formation between tertiary amines and a carbon nucleophile using hydrogen peroxide as the terminal oxidant is reported. This is the first report of a molecular iodine catalyzed cross-dehydrogenative coupling (CDC) reaction between two sp(3) C-H bonds.

Sequential Photo-oxidative [3 + 2] Cycloaddition/Oxidative Aromatization Reactions for the Synthesis of Pyrrolo[2,1-a]isoquinolines Using Molecular Oxygen as the Terminal Oxidant

We report an efficient method for the synthesis of pyrrolo[2,1-a]isoquinoline derivatives using sequential [3 + 2] cycloaddition/oxidative aromatization reactions catalyzed by methylene blue with fluorescent light irradiation under an oxygen atmosphere. The products were obtained in moderate to good yields.

Molecular-iodine-catalyzed aerobic photooxidative C–C bond formation between tertiary amines and carbon nucleophiles

This paper reports a useful method for molecular-iodine-catalyzed aerobic photooxidative C–C bond formation between tertiary amines and carbon nucleophiles. This reaction provides a practical method for C–C bond formation through the use of molecular iodine, harmless visible light irradiation, and molecular oxygen as the terminal oxidant.

Aerobic photooxidative direct asymmetric aldol reactions of benzyl alcohols using water as the solvent

We report an aerobic photooxidative direct asymmetric aldol reaction using water as the solvent. In this reaction, primary benzyl alcohols are oxidized into benzaldehydes under an oxygen atmosphere using anthraquinone-2-sodium sulfonate monohydrate as an organophotocatalyst. Stereoselective aldol reactions then proceed using a proline-type organocatalyst.

Organic dye-catalyzed radical ring expansion reaction

Herein, we reported an attractive method for synthesizing medium-sized rings that are catalyzed by erythrosine B under fluorescent light irradiation. This synthetic approach featured mild conditions, a facile procedure, a broad substrate scope, and moderate-to-good yields.