Alain Blanchet

Validation of a French adaptation of the Harvard Trauma Questionnaire among torture survivors from sub-Saharan African countries

Background : To date no validated instrument in the French language exists to screen for posttraumatic stress disorder (PTSD) in survivors of torture and organized violence. Objective : The aim of this study is to adapt and validate the Harvard Trauma Questionnaire (HTQ) to this population. Method: The adapted version was administered to 52 French-speaking torture survivors, originally from sub-Saharan African countries, receiving psychological treatment in specialized treatment centers. A structured clinical interview for DSM was also conducted in order to assess if they met criteria for PTSD. Results : Cronbachs alpha coefficient for the HTQ Part 4 was adequate (0.95). Criterion validity was evaluated using receiver operating characteristic curve analysis that generated good classification accuracy for PTSD (0.83). At the original cut-off score of 2.5, the HTQ demonstrated high sensitivity and specificity (0.87 and 0.73, respectively). Conclusion : Results support the reliability and validity of the French version of the HTQ. For the abstract or full text in other languages, please see Supplementary files under Reading Tools online

Comparative study of body image among dancers and anorexic girls

In order to examine the nature of body image distortions, we studied their perceptual and idealised components using a video distortion technique to create photographs of dancers, anorexics and controls that made their bodies look larger. Each subject was then asked to adjust the photograph until it reflected her estimated and desired body size. The results show that: 1) all three groups perceived themselves to be heavier than they actually are, but the dancers had a more realistic perception of their body weight; 2) the dancers would have liked to be thinner, whereas the controls and anorexics were satisfied with their body weight; 3) the scores of the anorexic subjects were characterised by a lack of correlation between their perceptual and idealised distortions, whereas those of the dancers — and even more so those of the controls — were characterised by consistency between the two types of distortion.

Left but not right hemisphere semantic processing abnormalities in language comprehension in subjects with schizotypy traits

Thought and language disorders in schizophrenia and schizotypy are thought to result from hemispheric dysfunction during semantic processing. Left hemisphere (LH) abnormalities are well established, but little is known about right hemisphere (RH) semantic processes. We explored hemispheric processing in 50 healthy volunteers assigned to high (h-SZT) or low schizotypy (l-SZT) group using the Schizotypal Personality Questionnaire (SPQ). Subjects were asked to make semantic judgments on sentence pair ending with a target that was either expected word (EW) or an unexpected word from the same (related violation, RV) or a different category (unrelated violation, URV). Targets were presented in a dichotic manner to the left or right ear. Analyses of reaction times in the l-SZT group showed semantic compatibility effect (URV-EW) in the LH and semantic memory activation effect (RV-URV) as well as semantic compatibility effect in the RH. The h-SZT group showed semantic memory activation but no semantic compatibility effect in the LH, the RH pattern resembling that of the l-SZT group. The magnitude of the LH semantic compatibility effect was inversely correlated with SPQ total scores and SPQ Cognitive-perceptual factor. Thus, RH semantic processes are effective and there is a deficit in LH focused activation in schizotypy.

DISCURSIVE STRATEGIES OF SUBJECTS WITH HIGH ALTITUDE HYPOXIA: EXTREME ENVIRONMENT

A discourse analysis was carried out on nine European lowlanders during a 2-month scientific expedition at high altitude including a 3-week stay in extreme survival conditions at the summit of Mt. Sajama (6542 m), in order to contribute to the understanding of psychological adaptation to extreme environments. This discourse analysis was part of a wide-ranging scientific investigation involving 12 scientific and medical research protocols which targeted human adaptation to high altitude chronic hypoxia. The objective of this study is to better understand the presence of linguistic markers capable of translating the subjects psychological state when faced with a threatening environment. This study was based on a method of propositional speech analysis developed by Ghiglione and Blanchet which emphasizes the cognitive function of verb categories, modalizers and adjuncts used by subjects. The method was developed in conjunction with psychopathological studies of the depressive state. Speech was recorded at time T1, 4 days after reaching the summit of Mt Sajama, and at time T2, 2 days before descending the mountain peak. These results revealed that in the absence of depression in any psychopathological sense of the word, normal subjects would react to their environment with a depressive component. However, the results of this study equally illustrate for some subjects a correspondence between those states with a depressive component and a physiological incomplete adaptation to high altitude. This correspondence could reflect the pathogenic effect of an adaptation deficit or could be in keeping with the literature concerning an incomplete adaptation effect induced by a latent depressive state.

An event‐related potential study of predictive and integrative semantic context processing in subjects with schizotypal traits

Context processing abnormalities may explain thought disorder in schizophrenia/schizotypy. This study aimed to assess predictive and integrative context processing in subjects with high or low scores on the Schizotypal Personality Questionnaire (SPQ). The N400 amplitude was recorded during semantic judgment of sentence pairs ending with a lateralized expected or unexpected word from the same or a different category (related and unrelated violation). In both groups, the N400 amplitude was less negative for expected words versus unrelated violations, regardless of which hemisphere received the stimulus, and for related versus unrelated violations, but only for left-hemisphere stimuli. The N400 amplitude for unrelated violations was less negative in subjects with high SPQ scores for both hemispheres. These results indicate that subjects with schizotypal traits use context to predict or integrate congruent words, but fail to inhibit incongruent words.

The “Weight” of Words on the Forearms During Relaxation

In this paper we examined the influence of repetition of weight-related sentences on the involuntary pressure forces of the forearms, when in a relaxed state. These forces were involuntary oscillations, exerted by muscle movements of the breathing-cycle and muscle movements of the arm on force sensors. We constructed a linguistic bio-mechanical system (Ablasmi), where in each arm of a padded relaxation chair contained special sensors that were specifically designed to detect the pressure forces of each forearm while participants listened to the specific recorded weight-related sentences. In this experiment we used some classic sentences, such as “your right/left arm is heavy,” inspired by Autogenic Training (Schultz in Le training autogene. Paris, PUF, 1974) and some sentences, such as “your right/left arm is made of lead,” inspired by Grossmann’s relaxation technique. We observed that when the recorded sentences were directed to the right arm there was a significant increase of involuntary pressure forces on the right forearm. Additionally, we observed the same effect on the left forearm for the sentences directed to the left forearm. Thus, we believe we have provided experimental evidence of a definite linguistic effect of weight-related sentences on the involuntary pressure forces of the forearms. The implications of these findings are discussed.

Effect of semantic coherence on episodic memory processes in schizophrenia

Schizophrenia is associated with severe episodic retrieval impairment. The aim of this study was to investigate the possibility that schizophrenia patients could improve their familiarity and/or recollection processes by manipulating the semantic coherence of to-be-learned stimuli and using deep encoding. Twelve schizophrenia patients and 12 healthy controls of comparable age, gender, and educational level undertook an associative recognition memory task. The stimuli consisted of pairs of words that were either related or unrelated to a given semantic category. The process dissociation procedure was used to calculate the estimates of familiarity and recollection processes. Both groups showed enhanced memory performances for semantically related words. However, in healthy controls, semantic relatedness led to enhanced recollection, while in schizophrenia patients, it induced enhanced familiarity. The familiarity estimates for related words were comparable in both groups, indicating that familiarity could be used as a compensatory mechanism in schizophrenia patients.

Event-related brain potential study of expectancy and semantic matching in schizotypy

Priming studies have revealed semantic processing abnormalities in subjects that display high schizotypal traits. The objective of the present study was to further elucidate the contribution of predictive (expectancy) and integrative (semantic matching) context processing to the semantic deficit described in schizotypy. Thirty-six participants were assigned into high or low schizotypy groups according to their score on the Schizotypal Personality Questionnaire (SPQ), and event-related brain potentials were recorded while these individuals performed semantic judgments based on asymmetrically associated word pairs. Viewed in one direction (forward), the target was highly predictable from the prime, whereas in the backward direction, the prime-to-target association was weak. It was assumed that the forward condition would be dependent on expectancy generation, while the backward condition would rely on semantic matching. In the low-SPQ group, forward and backward related words evoked a reduced (less negative) N400 amplitude compared to unrelated words, resulting in a significant forward and backward N400 priming effect, respectively. By contrast, only forward related words were facilitated in the high-SPQ group, resulting in significant forward priming and a lack of backward priming. Furthermore, the N400 amplitude for forward related words was less negative within the high-SPQ group in comparison to the low-SPQ group, which indicated easier semantic access to predictable words for high-SPQ individuals. Therefore, schizotypy may be associated with an imbalance in the use of predictive and integrative context processing strategies, namely preserved, if not over allocated, expectancy generation along with altered integration of unpredictable words due to semantic matching deficit.

Metaphorical conceptualizations of the body in psychopatology and poetry

The goal of our study is to identify several conceptualizations of the body expressed in the contexts of psychopathology and literature. We propose a specific categorization of literary sentences drawing on Conceptual Metaphor Theory (Lakoff and Johnson 1980; 1999) and Context-Limited Simulation Theory (Ritchie 2003; 200; 2008). Based on corpus data, we show that in psychiatric manuals the physical body is always reasoned in metaphoric terms of the BODY-CONTAINER category, thus with a high degree of non-specific attributes. In psychoanalysis manuals, the body is represented by “sexual-sensual sentences” or by abstract “notions”. Italian poetry offers an additional representation of the body with special focus on the organs and other body parts like “heart,” hand(s)”, “face”, but also “blood”, “chest”, “arm(s),” “eye(s)”,“breast(s)”, “head,” “flesh,” “skin”.

An Event Related Potentials Study of Semantic Coherence Effect during Episodic Encoding in Schizophrenia Patients

The objective of this electrophysiological study was to investigate the processing of semantic coherence during encoding in relation to episodic memory processes promoted at test, in schizophrenia patients, by using the N400 paradigm. Eighteen schizophrenia patients and 15 healthy participants undertook a recognition memory task. The stimuli consisted of pairs of words either semantically related or unrelated to a given category name (context). During encoding, both groups exhibited an N400 external semantic coherence effect. Healthy controls also showed an N400 internal semantic coherence effect, but this effect was not present in patients. At test, related stimuli were accompanied by an FN400 old/new effect in both groups and by a parietal old/new effect in the control group alone. In the patient group, external semantic coherence effect was associated with FN400, while, in the control group, it was correlated to the parietal old/new effect. Our results indicate that schizophrenia patients can process the contextual information at encoding to enhance familiarity process for related stimuli at test. Therefore, cognitive rehabilitation therapies targeting the implementation of semantic encoding strategies can mobilize familiarity which in turn can overcome the recollection deficit, promoting successful episodic memory performance in schizophrenia patients.