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Dive into the research topics where Alain Laurent is active.

Publication


Featured researches published by Alain Laurent.


Tetrahedron Letters | 2003

A stereoselective intramolecular Diels-Alder strategy for the tricyclo[9.3.1.03,8]pentadecane core of aromatic C-ring taxanes.

David Smil; Alain Laurent; Nidejda S Spassova; Alex G. Fallis

Abstract A stereoselective Lewis acid-catalyzed and chelation controlled intramolecular Diels–Alder entry into the tricyclo[9.3.1.03,8]pentadecane core of aromatic C-ring taxanes is described. The approach affords an efficient, high yield, access to aromatic C-ring taxanes variably functionalized at the C2, C4, C5, and C9 positions.


Archive | 2007

Iap bir domain binding compounds

Alain Laurent; Kim Hewitt; Stephen J. Morris; Patrick Bureau; Alain Boudreault; Scott Jarvis; James B. Jaquith


Archive | 2006

Bir domain binding compounds

Scott Jarvis; Alain Boudreault; Patrick Bureau; James B. Jaquith; Alain Laurent; Delphine Labit


Archive | 2001

Neuroprotective and anti-proliferative compounds

James B. Jaquith; Alexander Graham Fallis; John W. Gillard; Alain Laurent


Canadian Journal of Chemistry | 2004

Part 2: Efficient strategies for the construction of variably substituted bicyclo[5.3.1]undecenones (AB-taxane ring systems) and their conversion to tricyclo[9.3.1.03,8]pentadecenones (ABC taxane ring systems) and bicyclo[2.2.2]octanones

Nidia P. Villalva-Servin; Alain Laurent; Alex G. Fallis


Canadian Journal of Chemistry | 2004

Part 1: Efficient strategies for the construction of variably substituted bicyclo[5.3.1]undecenones (AB taxane ring systems)

Alain Laurent; Nidia P. Villalva-Servin; Pat Forgione; Peter D. Wilson; David Smil; Alex G. Fallis


Archive | 2009

FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS

Alain Laurent; Melanie Proulx; James B. Jaquith


Archive | 2009

Bridged secondary amines and use thereof as iap bir domain binding compounds

Alain Laurent; Melanie Proulx; Yannick Rose; James B. Jaquith; Stephen J. Morris


Archive | 2010

Hsp-90 binding compounds, compositions thereof, and their use fn the treatment of autoimmune and inflammatory diseases

Patrick Bureau; Jean-Hugues Fournier; James B. Jaquith; Alain Laurent; Yannick Rose; Melanie Proulx


Archive | 2017

Selective inhibitors of Tec and Src protein kinase families

Alain Laurent; Yannick Rose; James B. Jaquith

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