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Alain Lebrun

Rhône-Poulenc

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Publication

Featured researches published by Alain Lebrun.

Archive | 2001

From Random Screening of Chemical Libraries to the Optimization of FPP-Competitive Inhibitors of Farnesyltransferase

Patrick Mailliet; Abdel Laoui; Jean-Dominique Bourzat; Marc Capet; Michel Cheve; Alain Commercon; Norbert Dereu; Alain Lebrun; Jean-Paul Martin; Jean-Francois Peyronel; Christophe Salagnad; Fabienne Thompson; Martine Zucco; Jean-Dominique Guitton; Guy Pantel; Marie-Christine Bissery; Clive Brealey; Jacques Lavayre; Yves Lelièvre; Jean-François Riou; Patricia Vrignaud; Marc Duchesne; François Lavelle

Together with gene alterations of the p53 tumor suppressor gene, mutations of the ras genes represent the most frequent gene modification umancancers. Ras mutations are found in at least 90% of pancreas, 50% of colon, and 30% of both lung and thyroid cancers (1,2).

Archive | 1996

4,9-ethano-benzo(f)isoindole derivatives as farnesyl transferase inhibitors

Alain Commerçon; Alain Lebrun; Patrick Mailliet; Jean-Francois Peyronel; Fabienne Sounigo; Alain Truchon; Martine Zucco

Archive | 1996

Novel farnesyl transferase inhibitors, preparation thereof and pharmaceutical compositions containing same

Bernard Baudoin; Christopher J. Burns; Alain Commerçon; Alain Lebrun

Archive | 1996

Novel farnesyl transferase inhibitors, preparation thereof and pharmaceutical compositions containing said inhibitors

Bernard Baudoin; Christopher J. Burns; Alain Commerçon; Alain Lebrun

Archive | 1996

Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent

Bernard Baudoin; Christopher J. Burns; Alain Commerçon; Alain Lebrun

Archive | 2004

PRODUCTOS ARIL-HETEROAROMATICOS, COMPOSICIONES QUE LOS CONTIENEN Y SU UTILIZACION.

Patrick Mailliet; Alain Lebrun; Fabienne Thompson; Gilles Tiraboschi

Archive | 2004

PRODUCTOS N-ARIL-HETEROAROMATICOS, COMPOSICIONES QUE LES CONTIENEN Y SU UTILIZACION

Alain Lebrun; Fabienne Thompson; Gilles Tiraboschi; Salvino Joseph M; Patrick Mailliet

Archive | 2004

Produits aryl-heteroaromatiques, compositions les contenant et utilisation

Patrick Mailliet; Alain Lebrun; Fabienne Thompson; Gilles Tiraboschi

Archive | 2001

DERIVADOS DEL 4.9-ETANO-BENZO(F)ISOINDOL, COMO INHIBIDORES DE LA FARNESIL TRANSFERASA, Y LAS COMPOSICIONES FARMACÉUTICAS QUE LOS CONTIENEN

Martine Zucco; Alain Truchon; Fabienne Sounigo; Jean-Francois Peyronel; Alain Lebrun; Alain Commercon; Patrick Mailliet

Archive | 1996

DERIVES DE 4,9-ETHANO-BANZO(f)ISOINDOLE COMME INHIBITEURS DE FARNESYL TRANSFERASE

Alain Commercon; Alain Lebrun; Patrick Mailliet; Jean-Francois Peyronel; Fabienne Sounigo; Alain Truchon; Martine Zucco

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Collaboration

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Patrick Mailliet

Aventis Pharma

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Alain Commerçon

Rhône-Poulenc

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Bernard Baudoin

Rhône-Poulenc

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Christopher J. Burns

Rhône-Poulenc

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Fabienne Thompson

Aventis Pharma

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Jean-Francois Peyronel

Rhône-Poulenc

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Alain Commercon

Aventis Pharma

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Alain Truchon

Rhône-Poulenc

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Fabienne Sounigo

Rhône-Poulenc

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Gilles Tiraboschi

Aventis Pharma

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