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Dive into the research topics where Alan Deangelis is active.

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Featured researches published by Alan Deangelis.


Bioorganic & Medicinal Chemistry Letters | 2009

Discovery and SAR of para-alkylthiophenoxyacetic acids as potent and selective PPARδ agonists

Rui Zhang; Alan Deangelis; Aihua Wang; Ellen Sieber-McMaster; Xun Li; Ronald K. Russell; Patricia Pelton; Jun Xu; Peifang Zhu; Lubing Zhou; Keith T. Demarest; William V. Murray; Gee-Hong Kuo

Synthesis and SAR of para-alkylthiophenoxyacetic acids is described. Achiral compounds 30, 31 and 32 were identified as potent and selective PPARdelta agonists.


Journal of Medicinal Chemistry | 2003

Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3β Inhibitors

Gee-Hong Kuo; Catherine Prouty; Alan Deangelis; Lan Shen; David John O'Neill; Chandra R. Shah; Peter J. Connolly; William V. Murray; Bruce R. Conway; Peter K. Cheung; Lori Westover; Jun Z. Xu; Richard Look; Keith T. Demarest; Stuart Emanuel; Steven A. Middleton; Linda K. Jolliffe; Mary Pat Beavers; Xin Chen


Journal of Medicinal Chemistry | 2005

Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.

Gee-Hong Kuo; Alan Deangelis; Stuart Emanuel; Aihua Wang; Yan Zhang; Peter J. Connolly; Xin Chen; Robert H. Gruninger; Catherine A. Rugg; Angel R. Fuentes-Pesquera; Steven A. Middleton; Linda K. Jolliffe; William V. Murray


Archive | 2001

Pyrazine derivatives as modulators of tyrosine kinases

Gee-Hong Kuo; Peter J. Connolly; Catherine Prouty; Alan Deangelis; Aihua Wang; Linda Jolliffe; Steve Middleton; Stuart Emanuel


Journal of Medicinal Chemistry | 2005

Synthesis and discovery of pyrazine-pyridine biheteroaryl as a novel series of potent vascular endothelial growth factor receptor-2 inhibitors.

Gee-Hong Kuo; Aihua Wang; Stuart Emanuel; Alan Deangelis; Rui Zhang; Peter J. Connolly; William V. Murray; Robert H. Gruninger; Jan L. Sechler; Angel R. Fuentes-Pesquera; Dana L. Johnson; Steven A. Middleton; Linda K. Jolliffe; Xin Chen


Archive | 2001

Macroheterocylic compounds useful as kinase inhibitors

Gee-Hong Kuo; Han-Cheng Zhang; Catherine Prouty; Alan Deangelis; Peter J. Connolly; William V. Murray; Lan Shen; Bruce R. Conway; Keith T. Demarest; Chandra R. Shah; Bruce E. Maryanoff; Kimberly B. White


Journal of Medicinal Chemistry | 2005

Synthesis and structure-activity relationships of pyrazine-pyridine biheteroaryls as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors.

Gee-Hong Kuo; Catherine Prouty; Aihua Wang; Stuart Emanuel; Alan Deangelis; Yan Zhang; Fengbin Song; Lawrence Beall; Peter J. Connolly; Prahba Karnachi; Xin Chen; Robert H. Gruninger; Jan L. Sechler; Angel R. Fuentes-Pesquera; Steven A. Middleton; Linda K. Jolliffe; William V. Murray


Bioorganic & Medicinal Chemistry Letters | 2007

Discovery of para -alkylthiophenoxyacetic acids as a novel series of potent and selective PPARδ agonists

Rui Zhang; Aihua Wang; Alan Deangelis; Patricia Pelton; Jun Xu; Peifang Zhu; Lubing Zhou; Keith T. Demarest; William V. Murray; Gee-Hong Kuo


Archive | 2007

ACIDOS 4-((FENOXIALQUIL)TIO)-FENOXIACETICOS, Y ANALOGOS DE LOS MISMOS

Alan Deangelis; Keith T. Demarest; Patricia Pelton; Aihua Wang; Rui Zhang


Archive | 2005

4-((phenoxyalkyl)thio)-phenoxyacetic acid derivatives and use thereof as ppar modulators

Alan Deangelis; Keith T. Demarest; Gee-Hong Kuo; Patricia Pelton; Aihua Wang; Rui Zhang

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Linda K. Jolliffe

Scripps Research Institute

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Dana L. Johnson

Scripps Research Institute

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