Alba Montoya

Population genetics of eight new Y-chromosomal STR haplotypes in three Colombian populations: Antioquia, Chocó and Cartagena

Abstract In this study, eight new Y-chromosomal (GATA-C4, DYS438, DYS437, DYS461, GATA-H4, DYS439, GATA-A10 and DYS460) short tandem repeat (STR) polymorphic systems were typed by two PCR quadruplex reactions in three Colombian populations: Antioquia, Choco and Cartagena. GATA-C4 showed the highest gene diversity in the three populations. In the Antioquia population sample, a total of 123 different haplotypes were observed among which 85 were unique and 38 were found at least two times; in the Choco population sample: 55 different haplotypes, 47 unique and 8 at least two times; in the Cartagena population sample: 82 different haplotypes, 77 unique and 5 at least two times. The highest average gene diversity was found in Cartagena and the lowest was in Choco. The haplotype diversity for the eight Y-chromosomal STR loci in the Antioquia, Choco and Cartagena population samples were calculated to be 0.9949, 0.9959 and 0.9940, respectively.