Aleksandr A. Skaptsov

Structure of Composite Biocompatible Titania Coatings Modified with Hydroxyapatite Nanoparticles

The article describes prospective composite biocompatible titania coatings modified with hydroxyapatite nanoparticles and obtained on intraosseous implants fabricated from commercially pure titanium. Consistency changes of morphological characteristics and crystalline structure, mechanical properties and biocompatibility of experimental titanium implant coatings obtained by the combination of oxidation and surface modification with hydroxyapatite during induction heat treatment are defined.

Nanostructure of biocompatible titania/hydroxyapatite coatings

The article describes prospective composite biocompatible titania coatings modified with hydroxyapatite nanoparticles and obtained on intraosseous implants fabricated from commercially pure titanium VT1-00. Consistency changes of morphological characteristics, crystalline structure, physical and mechanical properties and biocompatibility of experimental titanium implant coatings obtained by the combination of oxidation and surface modification with hydroxyapatite during induction heat treatment are defined.

Titania coatings for high-tech devices

The article describes nanostructured titania coatings obtained on the surface of high-tech titanium devices. Consistency changes of the micro- and nanostructure, physico-mechanical and tribological characteristics of experimental coatings obtained by the induction heat treatment are defined.

In vitro metabolism study of normal and tumor cells when exposed to red LED light

This work presents the results of studying the mitochondrial membrane potential, intracellular ROS, peculiarities of the cell cycle of cancer cells HCT-116 and the normal line of CHO cells when exposed to the red LED light with a wavelength range of 0.620-0.680 μm. A dose-dependent increase in mitochondrial membrane potential and intracellular ROS concentration in cancer cells HCT-116 was established. In normal CHO cell line a dose-dependent reduction of mitochondrial membrane potential and dose-dependent increase in intracellular ROS occur. It has been shown that the sensitivity of the studied cell lines to the red light depends on the stage of the cell cycle.

Peculiarities of structure formation of layered metal-oxide system Ti-Ta-(Ti,Ta)xOy during electro-spark alloying and thermally stimulated modification

The study focuses on high-performance combined electro-spark alloying of titanium and titanium alloy (VT1-0, VT16) surface and porous matrix structure oxidation. The metal-oxide coatings morphology is the result of melt drop transfer, heat treatment, and oxidation. The study establishes the influence of technological regimes of alloying and oxidation on morphological heterogeneity of biocompatible layered metal-oxide system Ti-Ta-(Ti,Ta)xOy. It was found that during electro-spark alloying the concentration of tantalum on the titanium surface ranges from 0.1 to 3.2 at.%. Morphology of the deposited splats is represented by uniformly grown crystals of titanium and tantalum oxides, which increase from nano- to submicron size.

The study of the structural features of the lymphocytes in patients with diabetes using atomic force microscopy

The results of the study of morphological and biophysical parameters of the cell membrane of live lymphocytes in patients with insulin-dependent and non-insulin dependent diabetes mellitus and healthy donors using atomic force microscopy have been presented. It is found that lymphocytes from patients with diabetes are characterized by a decrease in volume and cell surface roughness compared to normal lymphocytes. An increase in the Youngs modulus of lymphocytes in patients with diabetes more than 3 times compared to normal rates has been shown. Increased stiffening of lymphocyte cytolemma in patients with non-insulin dependent diabetes mellitus leads to a decrease in its adhesive properties, unlike lymphocytes in patients with insulin-dependent diabetes mellitus.

Structural and chemical transformations on zirconium surface during machining and electrotechnological treatment with high-frequency currents

Research results on the chemical composition and surface morphological characteristics of zirconium products after machining and treatment with high-frequency currents are described. It was established that at the temperature range from 600 to 1200 °C and duration of heat treatment from 30 to 300 seconds oxide coatings consisting of nano-grains are formed.

Oxide-bioceramic coatings obtained on titanium items by the induction heat treatment and modified with hydroxyapatite nanoparticles

Prospective composite bioceramic titania coatings were obtained on intraosseous implants fabricated from cp-titanium and medical titanium alloy VT16 (Ti-2.5Al-5Mo-5V). Consistency changes of morphological characteristics, mechanical properties and biocompatibility of experimental titanium implant coatings obtained by oxidation during induction heat treatment are defined. Technological recommendations for obtaining bioceramic coatings with extremely high strength on titanium items surface are given.