Ali Can Kazandi

Psoriasiform contact dermatitis due to propolis in a beekeeper

BACKGROUND More than 250 cases of allergic contact dermatitis due to propolis have been described. A few of these occurred in beekeepers. OBJECTIVE To describe a case of psoriasiform dermatitis caused by propolis in a beekeeper who thought that his lesions were related to honeybee stings. METHODS A 45-year-old beekeeper experienced hand dermatitis for the past 5 years. He believed that the lesions occurred and worsened when he was stung by honeybees. He was prescribed topical corticosteroids several times, but because he was stung frequently, the drugs never helped control the lesions. In the past few years, he frequently had contact with propolis during honey collection, but he denied the role of propolis because he was wearing gloves while handling the beehives. For diagnostic evaluation, skin biopsy, skin prick tests (SPTs), identification of specific IgE antibodies, and atopic patch tests were performed. RESULTS Skin biopsy showed psoriasiform contact dermatitis. Results of SPTs to honeybee and serum specific IgE for Apis mellifera remained negative. Results of the atopic patch test performed using A mellifera SPT material were also negative in the first 20 minutes and on the second and third days. However, propolis showed a positive erythematopapular reaction on day 2. The patient never again worked as a beekeeper, and neither did he, as far as he knew, use any medical or cosmetic products that contained propolis. His hand lesions improved almost completely. CONCLUSION Dermatitis due to propolis should never be disregarded in beekeepers, and every effort should be put forth to make a correct diagnosis and to convince the patients of the cause.

Porokeratosis of Mibelli induced by topical corticosteroid

Background:  Porokeratosis of Mibelli is a chronic disorder characterised by slightly atrophic plaques surrounded by keratotic border.

Effect of BCG vaccine on peritoneal endometriotic implants in a rat model of endometriosis

Objective:  To investigate the effect of Bacillus Calmette–Guerin (BCG) vaccine on peritoneal implantation of endometrial tissue in rats.

Radiation recall reaction with anastrozole treatment in breast cancer

Our case is a 68-year-old postmenopausal female patient with suspicion of cancer in the right breast. Cancer was detected by mammography. Partial mastectomy and axillary dissection (in physical examination she had palpable lymph nodes in right axillary) were performed in February 2010. Pathologic staging of the patient was pT2N0M0. Diagnosis was invasive ductal carcinoma, with the tumor 4.5 cm in size, located in the lower inner quadrant; cellular grade, 3; nuclear grade, 2; modified Bloom and Richardson grade, 2. None of the 24 axillary nodes displayed metastatic involvement. Surgical margin was 1 cm. In immunohistochemical analysis, it was reported that estrogen receptor was 20% (+2), progesterone receptor 40% (+3), p53 10%, c-erb B2 (-), and Ki 67 30%. Chemotherapy was not considered due to the patients comorbidities (heart failure, diabetes mellitus) but radiotherapy, and afterward hormonal therapy regimens, were

White fibrous papulosis of the neck

A 56-year-old white man with multiple, discrete nonfollicular papules on the neck is presented. Clinical and histopathologic features were compatible with the entity of white fibrous papulosis of the neck (WFPN). Pseudoxanthoma elasticum–like papillary dermal elastolysis (PXE-PDE) and WFPN are further clinicopathologic patterns of intrinsic aging. Clinically, WFPN is characterized by isolated, whitish papules, whereas those of PXE-PDE are yellowish and often coalesce to form “cobblestone” plaques. Our case showed clearly marginated whitish papules. The major histopathologic feature of WFPN is superficial dermal fibrosis with scant elastolysis; in PXE-PDE, there is papillary dermal elastolysis but no sign of fibrosis. No recurrence was performed in the 3 years’ follow-up in our case. Surgical treatment may be considered in such cases with well-circumscribed lesions.

Subungual glomus tumor: surgical and histopathologic evaluation

Glomus tumor is a rare and benign vascular tumor, arising from neuromyoarterial glomus bodies. It is generally localized on the hand and especially the nail bed and is usually solitary. Pain, tenderness, and temperature sensitivity are the classic triad of symptoms of a glomus tumor. Owing to the small lesions and absence of specific skin features in the nail bed and nail matrix localizations, glomus tumor may not be taken into consideration. In particular, presentation of patients to practitioners of different disciplines for treatment of pain may cause diagnostic delays. Surgical excision is the most effective treatment approach and provides histopathologic diagnosis and rapid improvement of symptoms. This article describes a patient with a subungual glomus tumor for which surgical excision was performed.