Amanda do Couto e Silva

Plantas Medicinais da RENISUS Com Potencial Anti-inflamatório: Revisão Sistemática Em Três Bases de Dados Científicas

The inflammation is a response to acute tissue injury responsible for producing characteristic symptoms that lead to changes in tissue homeostasis and blood flow, as a defense mechanism of the immune system. However, chronic inflammation is a cause of many diseases like cancer, arteriosclerosis, diabetes and neurodegenerative diseases. Most anti-inflammatory drugs exert significant side effects that may limit their use. An alternative to such drugs are the medicinal plants, which provide an important approach for the identification of bioactive compounds. This systematic review aimed to quantify the clinical studies that relate therapeutic potential for inflammatory diseases from the study of plants RENISUS, published between 2010 and February 2013 in three scientific databases (SciELO, Science Direct and Springer). Of the 21 357 articles found in databases, analysis of articles was originally made from the title of journal reading, the chosen articles were subsequently assessed for Abstract. Finally, Articles chosen at this stage, the full text was analyzed. This analysis resulted in the selection of 44 studies of interest, which dealt with 20 different plants RENISUS.

ANÁLISE SISTEMÁTICA DA PRODUÇÃO CIENTÍFICA DO ZINGIBER OFFICINALE ROSCOE APÓS A CRIAÇÃO DA RELAÇÃO NACIONAL DE PLANTAS MEDICINAIS DE INTERESSE AO SISTEMA ÚNICO DE SAÚDE

Introduction: Ginger (Zingiber officinale Roscoe) is a native plant from Asia that has been used as a spice and medicinal compound for thousands of years. Many of its compounds have been isolated, identified, and studied due to their pharmacological effects. Objectives: Quantify clinical trials reporting some form of therapeutic action from the use of Z. officinale plant, which are listed on the National Medicinal Plants of Interest to the Unified Health System published between 2010 and 2013 in three scientific databases (SciELO, Science Direct and Springer). Material and Methods: We searched databases using the key search term “Zingiber officinale Roscoe.” A total of 757 articles were retrieved. We selected the studies dealing specifically with the term “Zingiber officinale ” or related terms such as “ginger,” “gingerol,” “gingerols,” “ginger,” and “ginger”. Reading the Abstract, we selected those that reported some kind of therapeutic treatment. In the last phase, the selected articles were fully read to search those proving therapeutic potentials from the study of Z. offic inale. Results: Thirty articles were included in this review. Six studies reported the antioxidant activity representing the most cited therapy. Conclusion: With the results, it is expected to be possible to guide further research on the species in question, including other diseases not yet explored.

The healing properties of medicinal plants used in the Brazilian public health system: a systematic review

OBJECTIVE The aim of this study was to conduct a systematic review of the healing potential of medicinal plants belonging to the Brazilian National List of Medicinal Plants of Interest to the Unified Health System (RENISUS). METHOD PubMed and ScienceDirect databases were searched for relevant articles, regardless of the language, from 2010 to June 2016. Two reviewers independently assessed study eligibility. Articles were included if they presented evidence of healing potential of medicinal plants. Only those available as full and open access texts were considered. RESULTS A total of 1381 articles met the inclusion criteria. Of these, 156 studies were considered eligible and were reviewed as full text. Following full analysis, 64 studies were included in this review. The studies covered 27 of the 71 plants belonging to RENISUS, nine of which are native to Brazil. In addition, two species are currently available in the Brazilian public health system as herbal medicine. CONCLUSION This review may encourage and contribute to the appropriate use of medicinal plants in the public health system in Brazil.

Potencial hepatoprotetor das plantas medicinais da renisus: revisão sistemática

Introducao: A lesao ou disfuncao hepatica e considerada um grave problema de saude. Os medicamentos sinteticos disponiveis para tratar doencas hepaticas sao caros e podem causar efeitos adversos com uso prolongado. Assim, os efeitos hepatoprotetores de plantas tem sido investigados. Objetivos: Quantificar as pesquisas que referem potencial terapeutico sobre doencas hepaticas a partir do estudo com plantas da RENISUS, publicados entre 2010 e maio de 2014 em duas bases de dados cientificas (SciELO e Science Direct ) e uma editora de revistas cientificas, Springer . Metodologia: A busca inicial resultou na selecao de 21.357 artigos encontrados nas bases de dados. A analise foi realizada primeiramente a partir da leitura do titulo das publicacoes. Os artigos selecionados nessa etapa foram avaliados por meio da leitura do abstract . Por fim, foi lido integralmente o texto dos artigos selecionados na etapa anterior, tendo sido selecionados estudos pre-clinicos e clinicos que comprovaram potencial terapeutico hepatoprotetor. Resultados: Esta selecao resultou em 13 artigos de interesse, dos quais cinco estudos foram realizados com a planta Curcuma longa . Conclusoes: Os resultados propiciam subsidios teoricos para discussoes no campo da Saude Publica sobre tratamentos alternativos a base de plantas medicinais como um coadjuvante terapeutico. Nesse sentido, a correta utilizacao dessas plantas, somada a terapia convencional, pode contribuir para a melhora da saude de pacientes com transtornos hepaticos.