Ana Corberán-Vallet

Multivariate exponential smoothing

This paper deals with the prediction of time series with correlated errors at each time point using a Bayesian forecast approach based on the multivariate Holt-Winters model. Assuming that each of the univariate time series comes from the univariate Holt-Winters model, all of them sharing a common structure, the multivariate Holt-Winters model can be formulated as a traditional multivariate regression model. This formulation facilitates obtaining the posterior distribution of the model parameters, which is not analytically tractable: simulation is needed. An acceptance sampling procedure is used in order to obtain a sample from this posterior distribution. Using Monte Carlo integration the predictive distribution is then approached. The forecasting performance of this procedure is illustrated using the hotel occupancy time series data from three provinces in Spain.

Prospective analysis of infectious disease surveillance data using syndromic information

In this paper, we describe a Bayesian hierarchical Poisson model for the prospective analysis of data for infectious diseases. The proposed model consists of two components. The first component describes the behavior of disease during nonepidemic periods and the second component represents the increase in disease counts due to the presence of an epidemic. A novelty of our model formulation is that the parameters describing the spread of epidemics are allowed to vary in both space and time. We also show how syndromic information can be incorporated into the model to provide a better description of the data and more accurate one-step-ahead forecasts. These real-time forecasts can be used to identify high-risk areas for outbreaks and, consequently, to develop efficient targeted surveillance. We apply the methodology to weekly emergency room discharges for acute bronchitis in South Carolina.

Prospective surveillance of multivariate spatial disease data

Surveillance systems are often focused on more than one disease within a predefined area. On those occasions when outbreaks of disease are likely to be correlated, the use of multivariate surveillance techniques integrating information from multiple diseases allows us to improve the sensitivity and timeliness of outbreak detection. In this article, we present an extension of the surveillance conditional predictive ordinate to monitor multivariate spatial disease data. The proposed surveillance technique, which is defined for each small area and time period as the conditional predictive distribution of those counts of disease higher than expected given the data observed up to the previous time period, alerts us to both small areas of increased disease incidence and the diseases causing the alarm within each area. We investigate its performance within the framework of Bayesian hierarchical Poisson models using a simulation study. An application to diseases of the respiratory system in South Carolina is finally presented.

A Bayesian SIRS model for the analysis of respiratory syncytial virus in the region of Valencia, Spain

We present a Bayesian stochastic susceptible-infected-recovered-susceptible (SIRS) model in discrete time to understand respiratory syncytial virus dynamics in the region of Valencia, Spain. A SIRS model based on ordinary differential equations has also been proposed to describe RSV dynamics in the region of Valencia. However, this continuous-time deterministic model is not suitable when the initial number of infected individuals is small. Stochastic epidemic models based on a probability of disease transmission provide a more natural description of the spread of infectious diseases. In addition, by allowing the transmission rate to vary stochastically over time, the proposed model provides an improved description of RSV dynamics. The Bayesian analysis of the model allows us to calculate both the posterior distribution of the model parameters and the posterior predictive distribution, which facilitates the computation of point forecasts and prediction intervals for future observations.

A Forecasting Support System Based on Exponential Smoothing

This chapter presents a forecasting support system based on the exponential smoothing scheme to forecast time-series data. Exponential smoothing methods are simple to apply, which facilitates computation and considerably reduces data storage requirements. Consequently, they are widely used as forecasting techniques in inventory systems and business planning. After selecting the most adequate model to replicate patterns of the time series under study, the system provides accurate forecasts which can play decisive roles in organizational planning, budgeting and performance monitoring.

Modeling Chickenpox Dynamics with a Discrete Time Bayesian Stochastic Compartmental Model

We present a Bayesian stochastic susceptible-exposed-infectious-recovered model in discrete time to understand chickenpox transmission in the Valencian Community, Spain. During the last decades, different strategies have been introduced in the routine immunization program in order to reduce the impact of this disease, which remains a public health’s great concern. Under this scenario, a model capable of explaining closely the dynamics of chickenpox under the different vaccination strategies is of utter importance to assess their effectiveness. The proposed model takes into account both heterogeneous mixing of individuals in the population and the inherent stochasticity in the transmission of the disease. As shown in a comparative study, these assumptions are fundamental to describe properly the evolution of the disease. The Bayesian analysis of the model allows us to calculate the posterior distribution of the model parameters and the posterior predictive distribution of chickenpox incidence, which facilitates the computation of point forecasts and prediction intervals.

A Bayesian stochastic SIRS model with a vaccination strategy for the analysis of respiratory syncytial virus

Our objective in this paper is to model the dynamics of respiratory syncytial virus in the region of Valencia (Spain) and analyse the effect of vaccination strategies from a health-economic point of view. Compartmental mathematical models based on differential equations are commonly used in epidemiology to both understand the underlying mechanisms that influence disease transmission and analyse the impact of vaccination programs. However, a recently proposed Bayesian stochastic susceptible-infected-recovered-susceptible model in discrete-time provided an improved and more natural description of disease dynamics. In this work, we propose an extension of that stochastic model that allows us to simulate and assess the effect of a vaccination strategy that consists on vaccinating a proportion of newborns.

Bayesian forecasting of demand time-series data with zero values

This paper describes the development of a Bayesian procedure to analyse and forecast positive demand time-series data with a proportion of zero values and a high level of variability for the non-zero data. The resulting forecasts play decisive roles in organisational planning, budgeting, and performance monitoring. Exponential smoothing methods are widely used as forecasting techniques in industry and business. However, they can be unsuitable for the analysis of non-negative demand time-series data with the aforementioned features. In this paper, an unconstrained latent demand underlying the observed demand is introduced into the linear heteroscedastic model associated with the Holt-Winters model. Accurate forecasts for the observed demand can readily be derived from those obtained with exponential smoothing for the latent demand. The performance of the proposed procedure is illustrated using a simulation study and two real time-series datasets which correspond to tourism demand and book sales.