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Dive into the research topics where Andrea J. Frangos is active.

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Featured researches published by Andrea J. Frangos.


American Journal of Roentgenology | 2009

Accuracy of MRI, MR Arthrography, and Ultrasound in the Diagnosis of Rotator Cuff Tears: A Meta-Analysis

Joseph O. de Jesus; Laurence Parker; Andrea J. Frangos; Levon N. Nazarian

OBJECTIVE The purpose of this study was to compare the diagnostic accuracy of MRI, MR arthrography, and ultrasound for the diagnosis of rotator cuff tears through a meta-analysis of the studies in the literature. MATERIALS AND METHODS Articles reporting the sensitivities and specificities of MRI, MR arthrography, or ultrasound for the diagnosis of rotator cuff tears were identified. Surgical (open and arthroscopic) reference standard was an inclusion criterion. Summary statistics were generated using pooled data. Scatterplots of the data sets were plotted on a graph of sensitivity versus (1 - specificity). Receiver operating characteristic (ROC) curves were generated. RESULTS Sixty-five articles met the inclusion criteria for this meta-analysis. In diagnosing a full-thickness tear or a partial-thickness rotator cuff tear, MR arthrography is more sensitive and specific than either MRI or ultrasound (p < 0.05). There are no significant differences in either sensitivity or specificity between MRI and ultrasound in the diagnosis of partial- or full-thickness rotator cuff tears (p > 0.05). Summary ROC curves for MR arthrography, MRI, and ultrasound for all tears show the area under the ROC curve is greatest for MR arthrography (0.935), followed by ultrasound (0.889) and then MRI (0.878); however, pairwise comparisons of these curves show no significant differences between MRI and ultrasound (p > 0.05). CONCLUSION MR arthrography is the most sensitive and specific technique for diagnosing both full- and partial-thickness rotator cuff tears. Ultrasound and MRI are comparable in both sensitivity and specificity.


Journal of The American College of Radiology | 2008

Musculoskeletal imaging: medicare use, costs, and potential for cost substitution.

Laurence Parker; Levon N. Nazarian; John A. Carrino; William B. Morrison; Gregory M. Grimaldi; Andrea J. Frangos; David C. Levin; Vijay M. Rao

PURPOSE The current study explores the substitution of ultrasound (US) for magnetic resonance imaging (MRI) of musculoskeletal (MSK) disorders by describing the recent use and costs of MSK imaging in the Medicare population, projecting these trends from 2006 to 2020, and estimating cost-savings involved in substituting MSK US for MSK MRI, when appropriate. METHODS The study used government-published data sets and de-identified Radiology Information System records exempt from institutional review board approval. From 1 years MSK MRI records (n = 3,621), the proportion of cases in which US could be substituted for MRI was estimated. The use rates for 4 modalities of MSK imaging and average costs were determined from government Medicare data sets from 1996 to 2005. Regression analysis was used to project use rates from 2006 to 2020. The effect on costs of substitution was calculated. RESULTS For the Medicare population, although there has been a moderate overall increase (25.7%) in MSK imaging, MSK MRI has increased 353.5% from 1996 to 2005. Projected MSK imaging costs in 2020 are


American Journal of Roentgenology | 2011

Bending the Curve: The Recent Marked Slowdown in Growth of Noninvasive Diagnostic Imaging

David C. Levin; Vijay M. Rao; Laurence Parker; Andrea J. Frangos; Jonathan H. Sunshine

3.6 billion, of which


Journal of The American College of Radiology | 2011

Trends in Utilization Rates of the Various Imaging Modalities in Emergency Departments: Nationwide Medicare Data From 2000 to 2008

Vijay M. Rao; David C. Levin; Laurence Parker; Andrea J. Frangos; Jonathan H. Sunshine

2.0 billion will be for MRI. A study of 3,621 MSK MRI reports indicates that 45.4% of primary diagnoses and 30.6% of all diagnoses could have been made with MSK US. The substitution of MSK US for MSK MRI, when appropriate, would lead to savings of more than


American Journal of Roentgenology | 2010

Geographic Variation in the Utilization of Noninvasive Diagnostic Imaging: National Medicare Data, 1998–2007

Laurence Parker; David C. Levin; Andrea J. Frangos; Vijay M. Rao

6.9 billion in the period from 2006 to 2020. CONCLUSION MRI MSK use has grown substantially from 1996 to 2005. The substitution of MSK US, when appropriate, would lead to large cost-savings for Medicare.


Journal of The American College of Radiology | 2010

How Widely Is Computer-Aided Detection Used in Screening and Diagnostic Mammography?

Vijay M. Rao; David C. Levin; Laurence Parker; Barbara Cavanaugh; Andrea J. Frangos; Jonathan H. Sunshine

OBJECTIVE The purpose of this article is to determine whether there has been any change in the rapid growth pattern that has characterized noninvasive diagnostic imaging in recent years. MATERIALS AND METHODS The annual nationwide Medicare Part B databases were used. All Current Procedural Terminology codes for discretionary noninvasive diagnostic imaging were identified. The overall utilization rates per 1,000 fee-for-service beneficiaries were calculated from 1998 through 2008, as were rates by modality. Determination was made as to whether studies were interpreted by radiologists or nonradiologist physicians. RESULTS The total utilization rate of noninvasive diagnostic imaging grew at a compound annual growth rate of 4.1% from 1998 to 2005, but this decreased to 1.4% from 2005 to 2008. From 2005 through 2008, the overall growth trends flattened dramatically for MRI and nuclear medicine and abated somewhat for CT, ultrasound, and echocardiography. In ambulatory settings, flattening of the advanced imaging growth curves was seen in both private offices and hospital outpatient facilities. From 1998 to 2005, the compound annual growth rate was 3.4% among radiologists and 6.6% among nonradiologist physicians. From 2005 to 2008, the compound annual growth rate decreased to 0.8% among radiologists and 1.8% among nonradiologists. CONCLUSION There has been a distinct slowing in the growth of discretionary noninvasive diagnostic imaging in the Medicare fee-for-service population since 2005. The slowdown has been most pronounced in MRI and nuclear medicine. This should allay some of the concerns of policymakers and payers. Both before and after 2005, growth was approximately twice as rapid among nonradiologist physicians as among radiologists.


Journal of The American College of Radiology | 2014

Continued Growth in Emergency Department Imaging Is Bucking the Overall Trends

David C. Levin; Vijay M. Rao; Laurence Parker; Andrea J. Frangos

PURPOSE To study utilization trends in the various imaging modalities in emergency departments (EDs) over a recent multiyear period. METHODS The nationwide Medicare Part B databases for 2000 to 2008 were queried. Medicares location codes were used to identify imaging examinations done on ED patients. All diagnostic imaging Current Procedural Terminology(®) codes were grouped by modality. For each code, the database provides procedure volume; utilization rates per 1,000 beneficiaries were then calculated. Medicares physician specialty codes were used to determine provider specialty. Utilization trends were studied between 2000 and 2008. RESULTS The overall utilization rate per 1,000 beneficiaries for all imaging in EDs increased from 281.0 in 2000 to 450.4 in 2008 (+60%). The radiography utilization rate rose from 227.3 in 2000 to 294.3 in 2008 (+29%, 67 accrued new studies per 1,000). The CT rate rose from 40.0 in 2000 to 130.7 in 2008 (+227%, 90.7 accrued new studies per 1,000). The ultrasound rate rose from 9.6 in 2000 to 18.7 in 2008 (+95%, 9.1 accrued new studies per 1,000). Other modalities had much lower utilization. In 2000, CT constituted 14% of all ED imaging, but by 2008, it constituted 29%. In 2008, radiologists performed 96% of all ED imaging examinations. CONCLUSIONS The rate of utilization of imaging is increasing in EDs. Growth is by far the most pronounced in CT, in terms of both the growth rate itself and the actual number of accrued new studies per 1,000 beneficiaries. Radiologists strongly predominate as the physicians of record for all ED imaging.


Journal of The American College of Radiology | 2009

Endovascular repair vs open surgical repair of abdominal aortic aneurysms: comparative utilization trends from 2001 to 2006.

David C. Levin; Vijay M. Rao; Laurence Parker; Andrea J. Frangos; Jonathan H. Sunshine

OBJECTIVE This study provides an overview of geographic variation in noninvasive diagnostic imaging utilization in the Medicare population over the period 1998 to 2007. MATERIALS AND METHODS The Centers for Medicare and Medicaid Services Physician Supplier Procedure Summary Master Files for 1998-2007 were the primary data source for the study. Physician Supplier Procedure Summary Master Files are an aggregation of the complete Part B Medicare billing records for all 32-37 million fee-for-service beneficiaries and provide the total number of each type of procedure performed, categorized by geographic regions. For the 10 Centers for Medicare and Medicaid Services geographic regions, we calculated the overall noninvasive diagnostic imaging procedure utilization rate and the ratio of the highest to lowest region (a relative risk statistic) for each year of the study. For the first and last years of the study, we calculated these numbers for 28 noninvasive diagnostic imaging categories. RESULTS In 2007, the Atlanta region had the highest utilization rate, with 4.60 procedures per capita, and Seattle had the lowest rate, with 2.99 procedures per capita. The relative risk was 1.54. Over the 10 years of the study, there was little change in the relative utilization rates of regions, and the relative risk ranged between 1.47 and 1.56. In 2007, bone densitometry showed the lowest regional relative risk (1.29), and cardiovascular PET showed the highest regional relative risk (70.2). Cardiovascular noninvasive diagnostic imaging and high-technology, high-cost noninvasive diagnostic imaging (e.g., MRI, PET, and nuclear medicine) showed high regional relative risk. CONCLUSION Regional variation is substantial--about 50% higher in the highest regions than in the lowest regions--but is not huge. Regional variation is increasing slightly. Cardiovascular and high-technology procedures show the greatest regional variation.


The Journal of Nuclear Medicine | 2013

VPAC1 Receptors for Imaging Breast Cancer: A Feasibility Study

Mathew L. Thakur; Kaijun Zhang; Adam C. Berger; B. Cavanaugh; Sung Kim; Chaitra Channappa; Andrea J. Frangos; Eric Wickstrom; Charles M. Intenzo

PURPOSE The aim of this study was to determine how widely computer-aided detection (CAD) is used in screening and diagnostic mammography and to see if there are differences between hospital facilities and private offices. METHODS The nationwide Medicare Part B fee-for-service databases for 2004 to 2008 were used. The Current Procedural Terminology(®) codes for screening and diagnostic mammography (both digital and screen film) and the CAD add-on codes were selected. Procedure volume was compared for screening vs diagnostic mammography and for hospital facilities vs private offices. RESULTS From 2004 to 2008, Medicare screening mammography volume increased slightly from 5,728,419 to 5,827,326 (+2%), but the use of screening CAD increased from 2,257,434 to 4,305,595 (+91%). By 2008, CAD was used in 74% of all screening mammographic studies. During this same time period, the Medicare volume of diagnostic mammography declined slightly from 1,835,700 to 1,682,026 (-8%), but the use of diagnostic CAD increased from 360,483 to 845,461 (+135%). By 2008, CAD was used in 50% of all diagnostic mammographic studies. In hospital facilities in 2008, CAD was used in 70% of all screening mammographic studies, compared with 81% in private offices. For diagnostic mammography in 2008, CAD was used in 48% in hospitals, compared with 55% in private offices. CONCLUSION Despite some operational drawbacks to using CAD, radiologists have embraced it in an effort to improve cancer detection. Its use has grown rapidly, and in 2008, it was used in three-quarters of all screening mammographic studies and half of all diagnostic mammographic studies. Women undergoing either screening or diagnostic mammography are more likely to receive CAD if they go to a private office than if they go to a hospital facility, although the differences are not great.


Journal of Vascular and Interventional Radiology | 2013

Single-center comparison of three chemoembolization regimens for hepatocellular carcinoma.

Nicholas Petruzzi; Andrea J. Frangos; Jonathan M. Fenkel; Steven K. Herrine; Hie-Won Hann; Simona Rossi; Ernest L. Rosato; David J. Eschelman; Carin F. Gonsalves; Daniel B. Brown

PURPOSE The aim of this study was to examine recent trends in imaging utilization in emergency departments (EDs) in the Medicare population. METHODS The 2002 to 2012 Medicare Part B databases were used. Imaging studies were categorized by modality. Medicares place-of-service codes identified those studies performed in ED patients. Specialty codes identified the specialties of the interpreting physicians. Utilization rates per 1,000 Medicare beneficiaries were calculated. Trends were assessed in plain radiography (XR), CT, noncardiac ultrasound, MRI, and nuclear medicine. RESULTS XR and CT were the most widely used modalities in ED patients. From 2002 to 2012, the XR utilization rate per 1,000 increased from 248.7 to 320.0 (+29%), and CT increased from 57.2 to 147.9 (+159%). Utilization rates of the other modalities were much lower. Ultrasound increased from 9.5 to 21.0 (+121%), while MRI increased from 1.4 to 5.1 (+264%). Growth in these 4 modalities was continuous and did not show the flattening that has characterized the utilization trends in other places of service. Nuclear medicine use was very low and remained essentially flat. During the study period, CT accrued 91 new examinations per 1,000, followed by XR at 71 and ultrasound at 11.5. The vast majority of examinations were interpreted by radiologists. CONCLUSIONS Despite the cessation of overall utilization growth of the various modalities in recent years, ED utilization rates continued to increase. The greatest increases, in terms of accrued new examinations per 1,000, were seen in CT and XR. This suggests that radiologists and ED physicians need to work together to better manage imaging utilization.

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Laurence Parker

Thomas Jefferson University Hospital

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David C. Levin

Thomas Jefferson University Hospital

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Vijay M. Rao

Thomas Jefferson University Hospital

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Jonathan H. Sunshine

American College of Radiology

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David J. Eschelman

Thomas Jefferson University

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Carin F. Gonsalves

Thomas Jefferson University

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Daniel B. Brown

Vanderbilt University Medical Center

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Charles M. Intenzo

Thomas Jefferson University

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Takami Sato

Thomas Jefferson University

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Jeffrey W. McCann

Thomas Jefferson University

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