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Dive into the research topics where Andrew Miller is active.

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Featured researches published by Andrew Miller.


Cell Calcium | 2016

Ca(2+) coding and decoding strategies for the specification of neural and renal precursor cells during development.

Marc Moreau; Isabelle Néant; Sarah Webb; Andrew Miller; Jean-François Riou; Catherine Leclerc

During embryogenesis, a rise in intracellular Ca(2+) is known to be a widespread trigger for directing stem cells towards a specific tissue fate, but the precise Ca(2+) signalling mechanisms involved in achieving these pleiotropic effects are still poorly understood. In this review, we compare the Ca(2+) signalling events that appear to be one of the first steps in initiating and regulating both neural determination (neural induction) and kidney development (nephrogenesis). We have highlighted the necessary and sufficient role played by Ca(2+) influx and by Ca(2+) transients in the determination and differentiation of pools of neural or renal precursors. We have identified new Ca(2+) target genes involved in neural induction and we showed that the same Ca(2+) early target genes studied are not restricted to neural tissue but are also present in other tissues, principally in the pronephros. In this review, we also described a mechanism whereby the transcriptional control of gene expression during neurogenesis and nephrogenesis might be directly controlled by Ca(2+) signalling. This mechanism involves members of the Kcnip family such that a change in their binding properties to specific DNA sites is a result of Ca(2+) binding to EF-hand motifs. The different functions of Ca(2+) signalling during these two events illustrate the versatility of Ca(2+) as a second messenger.


Archive | 2017

The Role of Ca2+ Signalling in the Differentiation of Embryonic Stem Cells (ESCs) into Cardiomyocytes

Baixia Hao; Wenjie Wei; Sarah Webb; Andrew Miller; Jianbo Yue


ISN Nature Genetics Forefronts Symposium on Nephrogenetics: from development to physiology, International Society of Nephrology and Nature Genetics, Denvers, MA, USA. | 2007

Investigating the role of Ca2+ signaling during early pronephros development in zebrafish embryos

Pui Ying Lam; Sarah Webb; Andrew Miller


14th Congress of Calcium Binding Proteins and Calcium Function in Health and Disease, La Palma, Spain | 2007

Cytokinetic Ca2+ transients: multiple response elements combine to facilitate the separation of daughter cells

Wai Ming Li; Sarah Webb; Andrew Miller


Archive | 2006

Offi cial journal of the Chinese Pharmacological Society and Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Heping Cheng; Sheng Wei; Li-ping Wei; Alexei Verkhratsky; Sarah Webb; Andrew Miller; Li-jun Yao; Gang Wang; Kunfu Ouyang; Chaoliang Wei; Xianhua Wang; Shi-Rong Wang; Wei Yao; Hong-Ping Huang; Jianhong Luo; Cai-hong Wu; Jie Liu; Zhuan Zhou; Qian Ge; Yongming Dong; Zhitao Hu; Zheng-Xing Wu; Tao Xu


Calcium Function in Development, Health and Disease: Applications in Biotechnology, HKUST, Hong Kong | 2004

Role of calcium in pronephros development. A new tool to study the autosomal dominant polycystic kidney disease (ADPKD)

Catherine Leclerc; Sarah Ho; Michel Fontes; Andrew Miller; Marc Moreau


The Biochemical Society, Calcium Oscillations and 5th UK Calcium Signalling Conference at University of Liverpool, Liverpool, Merseyside, UK | 2003

Evidence that Ca2+ inflow through liver cell store-operated Ca2+ channels utilises a thapsigargin-insensitive endoplasmic reticulum (Ca2+ + Mg2+) ATP-ase

Caroline Chan; Lyn Harland; Sarah Webb; Andrew Miller; Greg J. Barritt


ComBio2003, Melbourne Convention Centre, Melbourne, Australia | 2003

Evidence for a role for a small sub-region of the endoplasmic reticulum in the activation of liver cell store-operated Ca2+ channels obtained using targeted aequorins

Caroline Chan; Lyn Harland; Sarah Webb; Jinglong Chen; Andrew Miller; Greg J. Barritt


5th Australian and New Zealand Zebrafish Workshop at Auckland, New Zealand | 2003

Is Ca2+ involved in pronephros development in zebrafish?

Sarah Webb; Catherine Leclerc; Marc Moreau; Andrew Miller


The American Society for Cell Biology, 42nd Annual Meeting at San Francisco, CA, USA | 2002

Ca2+ signaling reinforces medio-lateral boundary definition during somitogenesis in zebrafish

Christina Leung; Sarah Webb; Andrew Miller

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Sarah Webb

Hong Kong University of Science and Technology

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Marc Moreau

Centre national de la recherche scientifique

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Marc Moreau

Centre national de la recherche scientifique

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S. Burtey

Aix-Marseille University

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Baixia Hao

University of Hong Kong

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