Arek Bibillo
Pacific Biosciences
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Publication
Featured researches published by Arek Bibillo.
Nucleosides, Nucleotides & Nucleic Acids | 2008
Jonas Korlach; Arek Bibillo; Jeffrey Wegener; Paul Peluso; Thang Pham; Insil Park; Sonya Clark; Geoff Otto; Stephen Turner
We demonstrate the efficient synthesis of DNA with complete replacement of the four deoxyribonucleoside triphosphate (dNTP) substrates with nucleotides carrying fluorescent labels. A different, spectrally separable fluorescent dye suitable for single molecule fluorescence detection was conjugated to each of the four dNTPs via linkage to the terminal phosphate. Using these modified nucleotides, DNA synthesis by φ29 DNA polymerase was observed to be processive for products thousands of bases in length, with labeled nucleotide affinities and DNA polymerization rates approaching unmodified dNTP levels. Results presented here show the compatibility of these nucleotides for single-molecule, real-time DNA sequencing applications.
Archive | 2005
Yue Xu; Jeffrey Wegener; Arek Bibillo
Archive | 2007
David Rank; Arek Bibillo; David Hanzel; Paul Peluso; Jeff Wegener
Archive | 2009
Keith Bjornson; Harold Lee; Jonas Korlach; Stephen Turner; Arek Bibillo; Fred Christians; Robin Emig; Molly He; Insil Park; Lei Jia; Andrei Fedorov; John Lyle
Archive | 2009
Sonya Clark; Arek Bibillo; Paul Peluso; Fred Christians; Molly He; Insil Park; Harold Lee; Keith Bjornson; Lei Jia; Robin Emig
Archive | 2009
Keith Bjornson; Arek Bibillo; Lubomir Sebo
Archive | 2010
Yue Xu; Jeffrey Wegener; Arek Bibillo
Archive | 2009
Keith Bjornson; Arek Bibillo; Fred Christians; Kevin Travers; Robin Emig
Archive | 2011
Keith Bjornson; Arek Bibillo; Fred Christians; Kevin Travers; Robin Emig; Stephen Turner
Archive | 2016
Satwik Kamtekar; Arek Bibillo; Keith Bjornson; Fred Christians; Colleen Cutcliffe; Jeremiah Hanes; Lei Jia; Walter Lee; Erik Miller; Pranav Patel
