Arianna Cerquiglini
University College London
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Publication
Featured researches published by Arianna Cerquiglini.
Journal of Biomedical Materials Research Part B | 2018
Arianna Cerquiglini; Johann Henckel; Harry Hothi; Anna Di Laura; John A. Skinner; Alister Hart
Metal release in patients with joint replacements is associated with local tissue reactions, pain, and ultimately revision of implants. One of the causes of this metal loss is speculated to be due to a mechanism of inflammatory cell-induced corrosion (ICIC). In this knee retrieval study, we aimed to: (1) identify the extent and location of ICI corrosion patterns on our femoral and tibial components and (2) correlate our findings with implant and clinical information. We investigated 28 femoral and 9 tibial components made of polished CoCr for presence of ICIC, using macroscopic and microscopic screening and statistical analyses to identify any significant correlations between our results and clinical information. We found that 71% of femoral and 100% of tibial components showed evidence of ICIC and significantly more was present on non-contacting regions (p < 0.0001). We found a significant correlation between the presence of ICIC and instability (p = 0.0113) and a significant difference between poster stabilized and cruciate retaining designs in the amount of ICIC on internal edges (p = 0.0375). This corrosion pattern was prevalent in our series of knee retrievals and may help explain some of the mechanisms of material loss that may occur in vivo.
Journal of Bone and Joint Surgery-british Volume | 2017
Harry Hothi; Johann Henckel; Paul R. Shearing; T. Holme; Arianna Cerquiglini; A. Di Laura; A. Atrey; John Skinner; Alister Hart
Aims The aim of this study was to compare the design of the generic OptiStem XTR femoral stem with the established Exeter femoral stem. Materials and Methods We obtained five boxed, as manufactured, implants of both designs at random (ten in total). Two examiners were blinded to the implant design and independently measured the mass, volume, trunnion surface topography, trunnion roughness, trunnion cone angle, Caput‐Collum‐Diaphyseal (CCD) angle, femoral offset, stem length, neck length, and the width and roughness of the polished stem shaft using peer‐reviewed methods. We then compared the stems using these parameters. Results We found that the OptiStems were lighter (p < 0.001), had a rougher trunnion surface (p < 0.001) with a greater spacing and depth of the machined threads (p < 0.001), had greater trunnion cone angles (p = 0.007), and a smaller radius at the top of the trunnion (p = 0.007). There was no difference in stem volume (p = 0.643), CCD angle (p = 0.788), offset (p = 0.993), neck length (p = 0.344), stem length (p = 0.808), shaft width (p = 0.058 to 0.720) or roughness of the polished surface (p = 0.536). Conclusion This preliminary investigation found that whilst there were similarities between the two designs, the generic OptiStem is different to the branded Exeter design.
International Orthopaedics | 2017
Anna Di Laura; Harry Hothi; Clement Battisti; Arianna Cerquiglini; Johann Henckel; John Skinner; Alister Hart
International Orthopaedics | 2017
Anna Di Laura; Harry Hothi; Johann Henckel; Arianna Cerquiglini; Ming Han Lincoln Liow; Young-Min Kwon; John Skinner; Alister Hart
Surface Topography: Metrology and Properties | 2018
Matthew Holland; Leigh Fleming; Karl Walton; Arianna Cerquiglini; Harry Hothi; Alister Hart; John Skinner; Paul J. Bills
Knee Surgery, Sports Traumatology, Arthroscopy | 2018
Arianna Cerquiglini; Johann Henckel; Harry Hothi; Niccolo Rotigliano; Michael T. Hirschmann; Alister Hart
Journal of Arthroplasty | 2018
Arianna Cerquiglini; Johann Henckel; Harry Hothi; Lorenzo Dall'Ava; Paul R. Shearing; Michael T. Hirschmann; Alister Hart
Bone and Joint Research | 2018
V. C. Panagiotopoulou; K. Davda; Harry Hothi; Johann Henckel; Arianna Cerquiglini; W.D. Goodier; John A. Skinner; Alister Hart; P. R. Calder
Archive | 2017
Arianna Cerquiglini; Johann Henckel; Harry Hothi; Niccolo Rotigliano; Matthew Holland; Paul J. Bills; Radu Racasan; John A. Skinner; Anna Hirschmann; Alister Hart
Knee | 2017
Arianna Cerquiglini; Harry Hothi; A. Di Laura; Johann Henckel; A. Eskelinen; M.T. Hirschmann; John A. Skinner; Alister Hart