Arumugam Jayamani

Hetero-metallic trigonal cage-shaped dimeric Ni3K core complex of L-proline ligand: Synthesis, structural, electrochemical and DNA binding and cleavage activities

AbstractHetero-metallic trigonal cage-shaped dimeric Ni3K core complex of L-proline ligand has been synthesized and characterized. Single crystal X-ray diffraction analysis showed that the hetero-metallic Ni(II)–K(I) complex has a dimeric structure with nine coordinated potassium atoms and six coordinated nickel atoms. The cyclic voltammograms of the complex exhibited two successive quasireversible reduction waves at (Epc1=−

Di-μ-hydroxido-κ(4) O:O-di-μ-perchlorato-κ(4) O:O'-bis-[(2,2'-bi-pyridine-κ(2) N,N')copper(II)].

E_{\text {pc}}^{1} = -

1,2-Bis(2-hy­droxy-5-methyl­benzyl­idene)hydrazine

1.02 V and Epc2=−

2-Hy­droxy-3-meth­oxy­methyl-5-methyl­benzaldehyde

E_{\text {pc}}^{2} = -

Synthesis, molecular structure, biological properties and molecular docking studies on Mn(II), Co(II) and Zn(II) complexes containing bipyridine-azide ligands.

1.33 V) and two successive irreversible oxidation waves (Epa1=

Synthesis of mononuclear copper(II) complexes of acyclic Schiff's base ligands: spectral, structural, electrochemical, antibacterial, DNA binding and cleavage activity.

E_{\text {pa}}^{1} =

Synthesis, structural, electrochemical, DNA interaction, antimicrobial and molecular docking studies on dimeric copper(II) complexes involving some potential bidentate ligands

0.95 V and Epa2=

Studies on nucleic acid/protein interaction, molecular docking and antimicrobial properties of mononuclear nickel(II) complexes of piperazine based Schiff base

E_{\text {pa}}^{2} =

Green-emitting phosphorescent iridium(III) complex: Structural, photophysical and electrochemical properties

1.45 V) versus Ag/AgCl in DMF solution. Interaction of the complex with calf-thymus DNA (CT DNA) has been studied using spectroscopic techniques. The complex is an avid DNA binder with a binding constant of 3.6 × 108 M−1. The complex showed efficient oxidative cleavage of supercoiled pBR322 DNA in the presence of the reducing agent hydrogen peroxide involving hydroxyl radical (∘OH) species. As evidenced from the control experiment, DNA cleavage in the presence of∘OH radical was inhibited by quenchers, viz. DMSO and KI. The complex showed in vitro antimicrobial activity against four bacteria and two fungi and the activity is greater than that of the free ligand. Graphical AbstractHetero-metallic trigonal cage-shaped dimeric Ni3K core complex of ligand L-proline was synthesized. The complex is an avid DNA binder. The complex showed efficient oxidative cleavage of supercoiled pBR322 DNA in the presence of H2O2 involving hydroxyl radical species.

Mono- and binuclear copper(II) complexes of the bipyridine ligand: Structural, electrochemical and biological studies

In the title binuclear copper(II) complex, [Cu2(ClO4)2(OH)2(C10H8N2)2], the CuII ion is coordinated in the form of a Jahn–Teller distorted octahedron by two bipyridine N atoms, two perchlorate O atoms and two hydroxide O atoms, and displays a distorted octahedral geometry. The molecule belongs to the symmetry point group C 2h. The CuII ion is located on a twofold rotation axis and the hydroxide and perchlorate ligands are located on a mirror plane. Within the dinuclear molecule, the Cu⋯Cu separation is 2.8614 (7) Å. The crystal structure exhibits O—H⋯O, C—H⋯O and π–π [centroid–centroid distance = 3.5374 (13) Å] interactions.