Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Ashis Saha.
ACS Medicinal Chemistry Letters | 2011
Ashis Saha; Xiang Yu; Jian Lin; Mercedes Lobera; Anurag Sharadendu; Srinivas Chereku; Nili Schutz; Dalia Segal; Yael Marantz; Dilara McCauley; Scot Middleton; Jerry Siu; Roland W. Bürli; Janet Buys; Michelle Horner; Kevin Salyers; Michael Schrag; Hugo M. Vargas; Yang Xu; Michele McElvain; Han Xu
We have discovered novel benzofuran-based S1P1 agonists with excellent in vitro potency and selectivity. 1-((4-(5-Benzylbenzofuran-2-yl)-3-fluorophenyl)methyl) azetidine-3-carboxylic acid (18) is a potent S1P1 agonist with >1000× selectivity over S1P3. It demonstrated a good in vitro ADME profile and excellent oral bioavailability across species. Dosed orally at 0.3 mg/kg, 18 significantly reduced blood lymphocyte counts 24 h postdose and demonstrated efficacy in a mouse EAE model of relapsing MS.
Archive | 2007
Roland W. Bürli; Victor J. Cee; Jennifer E. Golden; Brian A. Lanman; Susana C. Neira; Ashis Saha; Nili Schutz; Xiang Yu; Dilara McCauley; Mercedes Lobera; Yael Marantz; Jian Lin; Srinivasa Rao Cheruku; Pini Orbach; Anurag Sharadendu; Robert C. Penland; Kimberley Gannon; Sharon Shacham; Silvia Noiman; Oren M. Becker; Zhaoda Zhang
Archive | 2007
Ashis Saha; Xiang Y. Yu; Mercedes Lobera; Jian Lin; Srinivasa Rao Cheruku; Oren M. Becker; Yael Marantz; Nili Schutz
Archive | 2007
Jian Lin; Dongli Chen; Steffi Koerner; Rosa E. Melendez; Pradyumna Mohanty; Efrat Ben-Zeev; Merav Fichman; Yael Marantz; Oren M. Becker; Dilara McCauley; Pini Orbach; Ashis Saha; Sharon Shacham; Michael Xie
Archive | 2007
Efrat Ben-Zeev; Vincent Jacques; Yael Marantz; A. Sekar Reddy; Zhaoda Zhang; Oren M. Becker; Dilara Mccaulay; Pini Orbach; Sharon Shacham; Ashis Saha; Michael Xie
Archive | 2006
Oren M. Becker; Mercedes Lobera; Rosa E. Melendez; Anurag Sharadendu; Laurence Wu; Xiang Y. Yu; Dale S. Dhanoa; Srinivasa Rao Cheruku; Yael Marantz; Silvia Noiman; Merav Fichman; Hanoch Senderowitz; Sharon Shacham; Ashis Saha; Pini Orbach
Archive | 2006
Oren M. Becker; Rosa E. Melendez; Yael Marantz; Anurag Sharadendu; Merav Fichman; Mercedes Lobera; Hanoch Senderowitz; Srinivasa Rao Cheruku; Silvia Noiman; Xiang Y. Yu; Sharon Shacham; Laurence Wu; Ashis Saha; Pini Orbach; Dale S. Dhanoa
Archive | 2008
Oren M. Becker; Mercedes Lobera; Anurag Sharadendu; Laurence Wu; Rao Cheruku Srinivasa; Yael Marantz; Silvia Noiman; Merav Fichman; Hanoch Senderowitz; Sharon Shacham; Ashis Saha; Pini Orbach
Archive | 2008
Oren M. Becker; Ashis Saha; Srinivasa Rao Cheruku; Xiang Y. Yu; Jian Lin; Yael Marantz; Pili Schutz; Mercedes Lobera
Archive | 2008
Ashis Saha; Jian Lin; Srinivasa Rao Cheruku; Xian Y Yu; Roland W. Bürli; Victor J. Cee; Jennifer E. Golden; Brian A. Lanman
Collaboration
Dive into the Ashis Saha's collaboration.
