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Dive into the research topics where Ashok K. Trehan is active.

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Featured researches published by Ashok K. Trehan.


Journal of Medicinal Chemistry | 1988

Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids.

Joseph P. Sanchez; John M. Domagala; Susan Elizabeth Hagen; Carl L. Heifetz; Marland P. Hutt; Jeffry B. Nichols; Ashok K. Trehan


Journal of Medicinal Chemistry | 1992

Quinolone antibacterial agents. Synthesis and structure-activity relationships of a series of amino acid prodrugs of racemic and chiral 7-(3-amino-1-pyrrolidinyl)quinolones. Highly soluble quinolone prodrugs with in vivo pseudomonas activity

Joseph P. Sanchez; John M. Domagala; Carl L. Heifetz; Priebe; Josephine A. Sesnie; Ashok K. Trehan


Journal of Medicinal Chemistry | 1988

7-substituted 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acids: synthesis and biological activity of a new class of quinolone antibacterials.

John M. Domagala; Susan Elizabeth Hagen; Carl L. Heifetz; Marland P. Hutt; Thomas F. Mich; Joseph P. Sanchez; Ashok K. Trehan


Archive | 1986

5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents

Joseph P. Sanchez; Ashok K. Trehan


Archive | 1985

5-amino-6,8-difluoroquinolones as antibacterial agents

Ashok K. Trehan; Joseph P. Sanchez


Journal of Heterocyclic Chemistry | 1987

The synthesis of a pyrido[2,3-c]pyridazine: a cinnoline related to 6-fluoronalidixic acid

Joseph P. Sanchez; Ashok K. Trehan; Jeffry B. Nichols


Archive | 1985

1-cyclopropyl-6,7-dihalo-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid and their esters, useful as intermediates for preparing the 7-amine substituted naphthyridines

Thomas F. Mich; Joseph P. Sanchez; John M. Domagala; Ashok K. Trehan


Archive | 1988

Foerfarande Foer framstaellning of antibakteriska staellningen at the 7-substituted-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridin-3-carboxylic acids.

John M. Domagala; Ashok K. Trehan; Joseph P. Sanchez; Thomas F. Mich


Archive | 1986

5-amino and 5-hydroxy-6,8-difluorchinolone as antibacterial ingredients.

Ashok K. Trehan; Joseph P. Sanchez


Archive | 1986

5-amino-, 5-alkoxy- og 5-hydroxy-6-fluor-1,4-dihydro-4-oxo-quinolin-3-carboxylsyrederivater og farmaceutisk acceptable syreadditions- og basesalte deraf og farmaceutiske kompositioner indeholdende forbindelserne

Ashok K. Trehan; Joseph P. Sanchez

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