Asuman Kilitci

Diagnostic and Prognostic Importance of the Neutrophil Lymphocyte Ratio in Breast Cancer

BACKGROUND The aim of this study was to determine diagnostic and prognostic roles of the neutrophil to lymphocyte ratio (NLR) in breast cancer patients. To date, data are limited on associations of primary breast carcinoma (PBC) and benign proliferative breast disease (BPBD) with preoperative NLR values. MATERIALS AND METHODS Our study covered of 120 female patients with PBC and 50 with BPBD. Diagnostic values of NLR were estimated using sensitivity, specificity and areas under receiver operating characteristic curves (AUC). RESULTS NLR values were significantly higher in the PBC patients than in those with BPBD, with an AUC of 0.668 in the PBC case. The optimal cut-off for NLR was 2.96 and this was validated in the testing set, giving a sensitivity and a specificity of 79.7% and 76.2%, respectively, in PBC patients. CONCLUSIONS Preoperative high NLR is a significant diagnostic predictor of distinction of breast cancer from BPBD and elevated NLR is also an important prognostic marker for primary invasive breast cancer.

ECTOPIC DECIDUA IN THE ADIPOSE TISSUE OF THE ABDOMINAL WALL

Ectopic decidual transformation is an uncommon condition in the abdominal wall during laparotomy for a cesarean section for pregnancy. It occurs most often in the ovary, cervix, but also presents omentum, appendix and peritoneum. A case of ectopic decidua found in the anterior abdominal wall incidentally in a 30-year-old pregnant female is described. The lesion, 3cm in diameter that formed a nodule. Microscopic evaluation revealed decidualized cells which were large polygonal and eosinophilic, some with vacuolated cytoplasm. Pregnancy related ectopic deciduous develops with the effect of progesterone in pregnancy and it is a benign lesion. Although, its histological appearance is characteristic, differential diagnosis should be done carefully.

Hemosiderotic dermatofibroma mimicking melanoma in a 12-year-old boy: a case report

We report a case of hemosiderotic dermatofibroma presenting as a brown‐black‐colored nodule with peripheral extensions, which mimics melanoma. Histopathology showed completely benign features with no atypia or mitosis. Nodular extensions of childhood dermatofibromas may be related to the growth of the child not necessarily pointing to a malignant process.

Use of cyanoacrylate to prevent cerebrospinal fluid fistulas after cranial surgery

Abstract Purpose: Cerebrospinal fluid (CSF) fistula is one of the most common complications encountered after cranial surgeries. In cases where CSF fistula frequently appears due to surgical technique, dural sealants are used as auxiliary preparations to prevent CSF fistula and provide convenience to the surgeon. Materials and Methods: Data obtained from 128 number of cases where cyanoacrylate (CA) had been used for dural repair to prevent CSF fistula was evaluated, retrospectively. The cases of skull base and frontal sinus fractures where the primary repair had not been carried out were also included in the study. Results: The mean follow-up of all cases was 9,7 months. CSF fistula was not encountered in 121 of 128 cases. 4 of the cases developed CSF fistula in the early period. 3 of the cases presented with CSF fistula in the late period after discharge. No side effects due to hypersensitivity or preparation were encountered. Conclusion: CA can help dural repair against the development of CSF fistula by taking effect quickly. Also, it is a rapid anti-haemorrhagic agent. It can also be used after posterior fossa surgery, skull base surgery where dural repair is difficult, or during sinus repair.

Spinal intramedullary mature cystic teratoma in an adult

Abstract Spinal intramedullary teratoma is a rare tumour characterised with slow progression course. Although symptoms are generally mild, long-term complaints can be observed due to the slow progression. In this report, we discuss a 29-year-old female diagnosed as mature cystic teratoma in thoracolumbar junction.

Testicular fibrous hamartoma: A case report

Fibrous hamartoma (FH) of childhood is uncommon benign tumor. They are generally seen in the head and neck region, gastrointestinal system and lung. As in the case we report, they may also occur in other unusual sites such as groin and testis. The clinical presentation is almost always a mass or swelling. We hereby report a case with FH in atrophic testis which is unusual location and clinical presentation.