Atilla Senayli

Segmental neurofibromatosis : Report of two cases

Neurofibromatosis (NF), or von Recklinghausens disease is comprised of a heterogeneous group of disorders, primarily affecting the skin, soft tissue, bone and central nervous system. Segmental neurofibromatosis (SN) is a rare form of NF, characterized by “café‐au‐lait” macules, freckles, and/or neurofibromas limited to a body segment. There are approximately 150 cases reported in the English published work. Bilateral segmental neurofibromatosis is a rare subtype of SN, manifesting with bilateral involvement of the body segments. Herein, we report two patients with SN; one associated with pectus excavatum, and the other case diagnosed as bilateral segmental neurofibromatosis. Asymmetry of the skull and thorax, kyphoscoliosis and segmental bone hypertrophy of the leg are skeletal abnormalities previously reported with SN. To the best of our knowledge, this is the first case of SN in association with pectus excavatum.

Torsion of an Encysted Fluid Collection

Torsion of a cyst within the tunica vaginalis is a rare entity and clinical course can easily be confused with other diseases that cause acute scrotum. We report a 6-year-old child with 3 days of acute scrotum findings. Patient had surgery with the suspicion of testis torsion. Torsion of a cyst within the tunica vaginalis was found intraoperatively. In pathologic evaluation, a necrotic funicular cyst was diagnosed. Two different mechanisms were reported for the reason of this disease: hernia sac protrusion in the hydrocele sac and bell-clapper deformity. Our observations were on the side of bell-clapper deformity. We aimed to share our findings with this report.

Coexistence of sacral dimple, solitary collagenoma and mid‐dorsal hypertrichosis in a child with occult spinal dysraphism

blood complement C1 inhibitor activity. Clin Chim Acta 1988; 174:121–30. 6 Drouet C, Blanch A, Roche O et al. Mutation analysis of the C1NH gene. J Allergy Clin Immunol 2004; 114:S66–74. 7 Cichon S, Martin L, Hennies HC et al. Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III. Am J Hum Genet 2006; 79:1098–103. 8 Farsetti A, Misiti S, Citarella F et al. Molecular basis of estrogen regulation of the Hageman factor XII gene expression. Endocrinology 1995; 136:5076–83.

Evaluation the Anti-Diabetic Activity of Cherry Laurel (Laurocerasusofficinalis)

Purpose: Cherry laurel has been used as an anti-diabetic drug. In this study, we aimed to evaluate its antidiabetic activity at standard living conditions and under stress by an experimental study. Material and Method: Forty Wistar-Albino rats weighing 300–350 grams were used in this study. Four groups were structured: control, diabetic, glibenclamide and cherry laurel extract. Streptozotocin (50 mg/kg) was injected to induce diabetes. Cherry laurel extract was obtained from the seed of the fruit. Routine blood glucose, insulin, preand intraanesthesia blood glucose levels were measured and compared. The One-way ANOVA followed by Duncan post-hoc test was used for statistical analysis. Results: After the second week of the experiment, Extract 300 and Extract 600 groups had the lower glucose levels (p<0.05). Also, insulin levels measured at the last week of the study revealed that Extract 300 and Extract 600 groups had the highest results (p< 0.01). Glucose levels under stress conditions significantly changed for Extract 300 and glibenclamide group (p<0.05). Glucose level changed more obviously in the Extract 600 group (p<0.001) that means

Necessity of Teamwork for Paediatric Dermatologic Patients Visiting Pediatric Surgery

Dermatology and plastic surgery are responsible as the main departments in terms of visits for paediatric dermatology patients. In addition, other departments, such as pediatric surgery, examine some pediatric dermatology patients. Although the departments have common interests, cooperation with these departments for pediatric dermatology has not been studied before. As an expanding branch, treatments for pediatric dermatology diseases may degrade because of the disorganization among disciplines. This process will reduce the number of-attendance as a result of patient and family dissatisfaction. AbsTRACT Objective: Pediatric surgery is one of the departments treating some pediatric dermatology diseases. In this study, experience of pediatric surgeons were assessed for skin diseases. In addition, the interaction between the pediatric surgery and other relevant sections were examined. Material and Methods: Pediatric surgery documents between 2005 and 2011 were examined. Diagnoses, consultations, and changes in diagnosis were evaluated for dermatologic problems of the patients. Results: Three hundred and fifty-two pediatric surgical patients were examined due to dermatologic complaints. Seventy-five patients were consulted eighty times totally to other clinics. four patients were consulted twice and one patient was consulted three times. The diagnosis of 68 patients was changed after examination in different clinics. Conclusion: Clinical disciplines for the integration of pediatric visits are rarely evaluated in dermatological patients. In our opinion, these evaluations may assist in selection of pediatric dermatologic units and medical members. Clinics of possible integrations between the common treatments for these patients may be important to design.

Letter to the editor: reviewers.

We have published scientific papers since 2001 in peer-reviewed journals in areas of pediatric surgery, anaesthesiology, and in general medicine. Our observations are that the journal’s process in terms of organizations, submission system, tracking, and publications are all well organized in all of the diverse journals in many countries of the world. We think that what is lacking in the well-organized review process is the quality and attitude of the reviewers. From our experience, we get the impression that the reviewing policies and process of these journals have a great deal of variability from the published policies of these journals. Our published and unpublished articles littered with rejections. Rejection rate is approximately 10 times than acceptance. We have learned a great deal from these experiences. There might be three reasons for rejections: The quality of the writing is poor, the merit or the concordance of the articles might be inconsistent with the existing paradigm. For the two leading reasons (quality and merit), we continue to do better. In addition, our experience tells us that the reviewer’s attitude and quality contribute to the rejection of our manuscripts. An additional reason may be that there is an inherent bias toward countries not similar to the advanced countries in research. There are reports in the literature about reviewers, but these evaluations are not sufficient to understand the global reviewing philosophy. There are no universal standards to integrate or to standardize the reviewing process of manuscripts. The only criterion for the evaluation of a paper is the experience of the reviewer. Consequently, the problem in this criterion is how the experience of a reviewer can be measured. To our knowledge, this feature is not systemized, too. In conclusion, we observe that scientific studies and publishing are well designed and schematized at nearly all points of the processes. However, the reviewing process is unclear and incorporated with factors unknown to the

Xeroderma Pigmentosum Olan Bir Hastada Özofagus Dilatasyonu Yönetimi

be a choice for swallowing difficulties of these patients, we could not find a report giving the criterion of the problem. Besides, up to now, xseroderma pigmentosum and esophageal dystonia has not been reported yet. We experienced that patients in this situation could benefit from esophageal dilatation. Also, there has not been much reports giving information in detail for anesthesia management but we suggest that management of these patients within standard anesthetic procedures are not seemed to be harmful in early periods

SİGMOİD KOLON ELONGASYONUNUN VOLÜM RENDERİNG TEKNİĞİ İLE DEĞERLENDİRİLMESİ

Sigmoid colons have various measurements, shapes, and configurations for individuals. In this subject there are rare clinical trials to answer the question of sigmoidal colon maldevelopment predicting a risk for volvulus. Therefore, sigmoid colon measurement may be beneficial to decide for volvulus. In a study, sigmoid colon diameters were evaluated during abdominal surgeries and it was found that median length was 47 cm and median vertical mesocolon length was 13 cm. We report a 14-year-old female patient who has a sigmoidal colon measured as nearly 54 cm. We used tomographic equipments for this evaluation. We know that MRI technique was used for this purpose but, there has not been data for MRI predicting the sigmoidal volvulus. We hope that our findings by this evaluation can contribute to insufficient literature of sigmoidal elongation.

Can Spinal Bupivacaine Analgesia Treatment Make a Difference on Urinary Bladder Healing According to the Intramuscular Pethidine Analgesia Treatment in Rats

We designed a study to compare the healing levels found with intramuscular pethidine with those found with intrathecal local anesthetic treatments. The urinary bladder is suggested to be the most useful tissue in the evaluation of the effects of the drugs. Nineteen male, Sprague-Dawley rats weighing 200–300 g were used in this study. A sagittal section was made in the urinary bladder after suitable anesthesia and laparotomy. Bladders were closed with 5-0 plain catguts 5 min later. There were nine rats in the control group and pethidine (0.5 g/kg) was administered intramuscularly in the gluteal muscle region to treat pain after the operations. There were 11 rats in the study group and each received a spinal injection of 0.25% bupivacaine after the operation. Rats were followed for 7 days to define pain. Specimens, particularly the incised region of the bladder, were evaluated for inflammation and fibrosis. Grading scales were used for this purpose. Statistical analyses of the data were performed using the Chi-square test. Statistical analyses were nonsignificant for inflammation (p ≤ 0.151) and nonsignificant for fibrosis (p ≤ 0.105). The treatments may have the same effects on organ healing mechanisms. Statistical difference is not shown in this study, but use of other combinations of pain treatments to evaluate the healing may demonstrate which of these possibilities is true.