B. Sunil Kumar

TiCl4-Catalyzed Efficient One-Pot Synthesis of α α-Amino Phosphonates

α-Aminophosphonates are synthesized by three-component condensation of aldehydes, amines, and trimethylphosphite in acetonitrile by using TiCl4 as catalyst. Compared to conventional methods, this new method consistently has advantages, including excellent yields, short reaction times, and mild reaction conditions.

Efficient synthesis of benzo[g]-and benzo[h]chromene derivatives by one-pot three-component condensation of aromatic aldehydes with active methylene compounds and naphthols

A convenient procedure is reported for the synthesis of benzo[g]-and benzo[h]chromene derivatives via one-pot three-component condensation of aromatic aldehydes with malononitrile or ethyl cyanoacetate and 1-or 2-naphthol in the presence of 10 mol % of titanium tetrachloride as catalyst. The reactions require no solvent; they are characterized by simple experimental procedure and easy isolation and can be performed on enlarged scale.

Vanadium(III) chloride as an effective catalyst for the Pechmann reaction

Good yields of substituted coumarins were obtained by a synthetic method involving the Pechmann reaction using vanadium(III)chloride (VCl3) reagent to effect this condensation under solvent-free conditions.

A mild and efficient tetrahydropyranylation and detetrahydropyranylation of alcohols and phenols by VCl3

Vanadium chloride is found to be an efficient catalyst for the tetrahydropyranylation and detetrahydropyranylation of various alcohols and phenols, giving good yields at room temperature and short reaction times.