Barney J. Magerlein
Upjohn
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Featured researches published by Barney J. Magerlein.
Advances in Applied Microbiology | 1971
Barney J. Magerlein
Publisher Summary The chapter gives an account of the modification of lincomycin. The fermentation broth of streptomyces lincolnensis var. lincolnensis, a new species of streptomycete isolated from a soil sample collected in Gering, Nebraska, was found to contain a new antibiotic, named lincomycin. The announcement by Mason and coworkers of the discovery of lincomycin coincided with chemical and physical characterization of the crystalline hydrochloride. Initial reports indicated that lincomycin possessed good in vitro and in vivo potency against a variety of gram-positive microorganisms. The chapter lists lincomycin-related antibiotics, such as Celesticetin and Lincomycins. It describes the clinical modification of lincomycins and microbial modification of lincomycins and clindamycin, giving details of sulfoxide formation and phosphorylation. Chemical and microbial modifications of lincomycin have succeeded in producing derived antibiotics possessing greater potency, extended spectrum including antiparasitic activity, improved taste, and varied absorption characteristics.
Tetrahedron | 1958
Barney J. Magerlein; John A. Hogg
Abstract The preparation of aromatic A ring 9//10 secosteroids via the pyrolysis of unsaturated 3,11-diketosteroids is described.
Journal of the American Chemical Society | 1945
H. L. Haller; Paul D. Bartlett; Nathan L. Drake; Melvin S. Newman; Stanley J. Cristol; Charles M. Eaker; Robert A. Hayes; Glen W. Kilmer; Barney J. Magerlein; George P. Mueller; Abraham Schneider; William B. Wheatley
Journal of the American Chemical Society | 1964
Herman Hoeksema; Brian Bannister; Robert D. Birkenmeyer; Barney J. Magerlein; F. A. MacKellar; W. Schroeder; G. Slomp; Ross R. Herr
Archive | 1958
George B Spero; Barney J. Magerlein; William P. Schneider; John A. Hogg
Journal of the American Chemical Society | 1956
George B Spero; J. L. Thompson; Barney J. Magerlein; A. R. Hanze; H. C. Murray; O. K. Sebek; John A. Hogg
Journal of the American Chemical Society | 1967
Barney J. Magerlein; Robert D. Birkenmeyer; Ross R. Herr
Journal of the American Chemical Society | 1953
David I. Weisblat; Barney J. Magerlein; D. R. Myers
Archive | 1968
Barney J. Magerlein
Antimicrobial Agents and Chemotherapy | 1966
Barney J. Magerlein; Robert D. Birkenmeyer