Benjamin E. Smith

Marine Ice Sheet Collapse Potentially Under Way for the Thwaites Glacier Basin, West Antarctica

Antarctic Collapse The West Antarctic Ice Sheet (WAIS) is particularly vulnerable to ocean warming-induced collapse. The Thwaites Glacier of West Antarctica is one of the largest WAIS regional contributors to sea level rise, and has been considered to be potentially unstable for many years. Joughin et al. (p. 735) used a combination of a numerical model and observations of its recent geometry and movement to investigate the stability of the Thwaites Glacier. The glacier has already entered the early stages of collapse, and rapid and irreversible collapse is likely in the next 200 to 1000 years. The onset of rapid collapse of the Thwaites Glacier in West Antarctica is likely within the next 200 to 1000 years. Resting atop a deep marine basin, the West Antarctic Ice Sheet has long been considered prone to instability. Using a numerical model, we investigated the sensitivity of Thwaites Glacier to ocean melt and whether its unstable retreat is already under way. Our model reproduces observed losses when forced with ocean melt comparable to estimates. Simulated losses are moderate (<0.25 mm per year at sea level) over the 21st century but generally increase thereafter. Except possibly for the lowest-melt scenario, the simulations indicate that early-stage collapse has begun. Less certain is the time scale, with the onset of rapid (>1 mm per year of sea-level rise) collapse in the different simulations within the range of 200 to 900 years.

Synchronous retreat and acceleration of southeast Greenland outlet glaciers 2000-06 : ice dynamics and coupling to climate

A large portion of the recent increase in the rate of mass loss from the Greenland ice sheet is from increased outlet glacier discharge along its southeastern margin. While previous investigations of the region’s two largest glaciers suggest that acceleration is a dynamic response to thinning and retreat of the calving front, it is unknown whether this mechanism can explain regional acceleration and what forcing is responsible for initiating rapid thinning and retreat. We examine seasonal and interannual changes in ice-front position, surface elevation and flow speed for 32 glaciers along the southeastern coast between 2000 and 2006. While substantial seasonality in front position and speed is apparent, nearly all the observed glaciers show net retreat, thinning and acceleration, with speed-up corresponding to retreat. The ratio of retreat to the along-flow stress-coupling length is proportional to the relative increase in speed, consistent with typical ice-flow and sliding laws. This affirms that speed-up results from loss of resistive stress at the front during retreat, which leads to along-flow stress transfer. Large retreats were often preceded by the formation of a flat or reverse-sloped surface near the front, indicating that subsequent retreats were influenced by the reversed bed slope. Many retreats began with an increase in thinning rates near the front in the summer of 2003, a year of record high coastal-air and sea-surface temperatures. This anomaly was driven in part by recent warming, suggesting that episodes of speed-up and retreat may become more common in a warmer climate.

Committed sea-level rise for the next century from Greenland ice sheet dynamics during the past decade

We use a three-dimensional, higher-order ice flow model and a realistic initial condition to simulate dynamic perturbations to the Greenland ice sheet during the last decade and to assess their contribution to sea level by 2100. Starting from our initial condition, we apply a time series of observationally constrained dynamic perturbations at the marine termini of Greenland’s three largest outlet glaciers, Jakobshavn Isbræ, Helheim Glacier, and Kangerdlugssuaq Glacier. The initial and long-term diffusive thinning within each glacier catchment is then integrated spatially and temporally to calculate a minimum sea-level contribution of approximately 1 ± 0.4 mm from these three glaciers by 2100. Based on scaling arguments, we extend our modeling to all of Greenland and estimate a minimum dynamic sea-level contribution of approximately 6 ± 2 mm by 2100. This estimate of committed sea-level rise is a minimum because it ignores mass loss due to future changes in ice sheet dynamics or surface mass balance. Importantly, > 75% of this value is from the long-term, diffusive response of the ice sheet, suggesting that the majority of sea-level rise from Greenland dynamics during the past decade is yet to come. Assuming similar and recurring forcing in future decades and a self-similar ice dynamical response, we estimate an upper bound of 45 mm of sea-level rise from Greenland dynamics by 2100. These estimates are constrained by recent observations of dynamic mass loss in Greenland and by realistic model behavior that accounts for both the long-term cumulative mass loss and its decay following episodic boundary forcing.

Germ Cell Migration Across Sertoli Cell Tight Junctions

Observing Sperm Factories The blood-testis barrier creates a permissive microenvironment for germ cell differentiation and protects meiotic germ cells from autoimmunity. To become sperm, large cysts of germline progenitors must cross the blood-testis barrier without causing damage. Smith and Braun (p. 798, published online 20 September) show that somatic Sertoli cells, the gate-keepers of the blood-testis barrier, manage this task by building a network of compartments bounded by old and new tight junctions. Intercellular bridges, which connect germ cells within cysts, span the transient compartments by passing through vertical strands at tricellular junctions. Only after the formation of a new blood-testis barrier are old tight junctions removed and germ cells released. Syncytial germ cell chains span a network of transient compartments to cross the blood-testis barrier in adult mice. The blood-testis barrier includes strands of tight junctions between somatic Sertoli cells that restricts solutes from crossing the paracellular space, creating a microenvironment within seminiferous tubules and providing immune privilege to meiotic and postmeiotic cells. Large cysts of germ cells transit the Sertoli cell tight junctions (SCTJs) without compromising their integrity. We used confocal microscopy to visualize SCTJ components during germ cell cyst migration across the SCTJs. Cysts become enclosed within a network of transient compartments fully bounded by old and new tight junctions. Dissolution of the old tight junctions releases the germ cells into the adluminal compartment, thus completing transit across the blood-testis barrier. Claudin 3, a tight junction protein, is transiently incorporated into new tight junctions and then replaced by claudin 11.

Radio-frequency attenuation beneath Siple Dome,West Antarctica, from wide-angle and profiling radar observations

Abstract Knowledge of the spatial distribution of bed lubrication regimes, i.e. frozen vs wet conditions, is crucial for understanding ice-sheet flow. Radar sounding can probe differing reflectivities between wet and frozen beds, but is limited by uncertainty in attenuation within the ice of bed echoes. Here we present two methods to estimate attenuation: (1) wide-angle radar sounding, in which source and receiver locations are varied so as to vary propagation path length, and thus echo amplitude; and (2) profiling, inwhich similar variations are obtained by sounding through varying ice thicknesses (assuming constant bed reflectivity). Siple Dome, West Antarctica, provides unusually favorable circumstances for application of these methods: the bed beneath Siple Dome is flat and uniform in its radar reflectivity, while ice thickness varies by several hundred meters. Wide-angle data 4 km from the summit yield an estimate for characteristic attenuation length of 124 m (35 dB km–1 loss), whereas profiling yields an estimate of 168 m.The difference between estimates is modest compared to the range of attenuation lengths reported in the literature. It may nonetheless prove informative by bounding effects of two ice properties to which the methods respond differently: (1) wide-angle sounding sampled relatively warm (lossy) ice beneath the summit, whereas the profiling method sampled relatively cold ice beneath the flanks as well; and (2) strain-induced crystal orientation fabrics and resulting dielectric anisotropy in the ice would vary from summit to flank, and may influence wide-angle sounding more strongly than profiling.

Androgen-dependent sertoli cell tight junction remodeling is mediated by multiple tight junction components.

Sertoli cell tight junctions (SCTJs) of the seminiferous epithelium create a specialized microenvironment in the testis to aid differentiation of spermatocytes and spermatids from spermatogonial stem cells. SCTJs must be chronically broken and rebuilt with high fidelity to allow the transmigration of preleptotene spermatocytes from the basal to adluminal epithelial compartment. Impairment of androgen signaling in Sertoli cells perturbs SCTJ remodeling. Claudin (CLDN) 3, a tight junction component under androgen regulation, localizes to newly forming SCTJs and is absent in Sertoli cell androgen receptor knockout (SCARKO) mice. We show here that Cldn3-null mice do not phenocopy SCARKO mice: Cldn3(-/-) mice are fertile, show uninterrupted spermatogenesis, and exhibit fully functional SCTJs based on imaging and small molecule tracer analyses, suggesting that other androgen-regulated genes must contribute to the SCARKO phenotype. To further investigate the SCTJ phenotype observed in SCARKO mutants, we generated a new SCARKO model and extensively analyzed the expression of other tight junction components. In addition to Cldn3, we identified altered expression of several other SCTJ molecules, including down-regulation of Cldn13 and a noncanonical tight junction protein 2 isoform (Tjp2iso3). Chromatin immunoprecipitation was used to demonstrate direct androgen receptor binding to regions of these target genes. Furthermore, we demonstrated that CLDN13 is a constituent of SCTJs and that TJP2iso3 colocalizes with tricellulin, a constituent of tricellular junctions, underscoring the importance of androgen signaling in the regulation of both bicellular and tricellular Sertoli cell tight junctions.

Light propagation in firn: application to borehole video

Borehole optical stratigraphy (BOS) is a borehole video system and processing routine for investigating polar firn. BOS records brightness variations in the firn and is effective at identifying stratigraphic markers. BOS brightness logs have been used to count annual layers and measure vertical strain, even though a specific cause of the brightness variations has not been determined. Here we combine two models of light transport to examine potential errors with BOS and identify improvements which will allow the system to estimate optical grain size. We use a Monte Carlo radiative transfer model to estimate the influence of firn microstructure variations on borehole reflectance. We then use a ray-tracing algorithm to model the multiple reflections within the borehole that cause measured brightness variations. Multiple reflections cause the brightness measured at a point on the borehole wall to not necessarily be equal to the local wall reflectance. The ray tracing further shows that wall imperfections or variations in the camera position can produce brightness variations that are unrelated to changes in firn properties. Smooth walls and good stabilization of the camera help ensure that brightness variations result from variations in firn properties, and thus are a measure of firn stratigraphy, rather than artifacts.

Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression.

The Y-box proteins YBX2 and YBX3 bind RNA and DNA and are required for metazoan development and fertility. However, possible functional redundancy between YBX2 and YBX3 has prevented elucidation of their molecular function as RNA masking proteins and identification of their target RNAs. To investigate possible functional redundancy between YBX2 and YBX3, we attempted to construct Ybx2 -/- ;Ybx3 -/- double mutants using a previously reported Ybx2 -/- model and a newly generated global Ybx3 -/- model. Loss of YBX3 resulted in reduced male fertility and defects in spermatid differentiation. However, homozygous double mutants could not be generated as haploinsufficiency of both Ybx2 and Ybx3 caused sterility characterized by extensive defects in spermatid differentiation. RNA sequence analysis of mRNP and polysome occupancy in single and compound Ybx2/3 heterozygotes revealed loss of translational repression almost exclusively in the compound Ybx2/3 heterozygotes. RNAseq analysis also demonstrated that Y-box protein dose-dependent loss of translational regulation was inversely correlated with the presence of a Y box recognition target sequence, suggesting that Y box proteins bind RNA hierarchically to modulate translation in a range of targets.

Observed rapid bedrock uplift in Amundsen Sea Embayment promotes ice-sheet stability

A quick rebound for Antarctic crust Earths crust deforms under the load of glaciers and ice sheets. When these masses are removed, the crust rebounds at a time scale determined by the viscosity of the upper mantle. Using GPS, Barletta et al. found that the viscosity of the mantle under the West Antarctic Ice Sheet is much lower than expected. This means that as ice is lost, the crust rebounds much faster than previously expected. Although estimates of total ice loss have to be revised upward, the surprising finding indicates that the ice sheet may stabilize against catastrophic collapse. Science, this issue p. 1335 A new viscosity model requires a much lower viscosity under the Amundsen Sea Embayment, stabilizing the Antarctic Ice Sheet. The marine portion of the West Antarctic Ice Sheet (WAIS) in the Amundsen Sea Embayment (ASE) accounts for one-fourth of the cryospheric contribution to global sea-level rise and is vulnerable to catastrophic collapse. The bedrock response to ice mass loss, glacial isostatic adjustment (GIA), was thought to occur on a time scale of 10,000 years. We used new GPS measurements, which show a rapid (41 millimeters per year) uplift of the ASE, to estimate the viscosity of the mantle underneath. We found a much lower viscosity (4 × 1018 pascal-second) than global average, and this shortens the GIA response time scale to decades up to a century. Our finding requires an upward revision of ice mass loss from gravity data of 10% and increases the potential stability of the WAIS against catastrophic collapse.

Has a marine ice sheet collapse begun in the Thwaites Glacier basin, West Antarctica?

Coordinates in polar stereographic format with standard lat of 71S, 0 deg rotation. Surface Mass Balance (SMB) values are in water equivalent units (m/yr). Contact Ian Joughin, ian@apl.washington.edu, for further information.