Beril Dogu

Blind or ultrasound-guided corticosteroid injections and short-term response in subacromial impingement syndrome: a randomized, double-blind, prospective study.

ObjectiveThe aim of this study was to compare the accuracy of blind vs. ultrasonography-guided corticosteroid injections in subacromial impingement syndrome and determine the correlation between accuracy of the injection location and clinical outcome. DesignForty-six patients with subacromial impingement syndrome were randomized for ultrasonography-guided (group 1, n = 23) and blind corticosteroid injections (group 2, n = 23). Magnetic resonance imaging analysis was performed immediately after the injection. Changes in shoulder range of motion, pain, and shoulder function were recorded. All patients were assessed before the injection and 6 wks after the injection. ResultsAccurate injections were performed in 15 (65%) group 1 patients and in 16 (70%) group 2 patients. There was no statistically significant difference in the injection location accuracy between the two groups (P > 0.05). At the end of the sixth week, regardless of whether the injected mixture was found in the subacromial region or not, all of the patients showed improvements in all of the parameters evaluated (P < 0.05). ConclusionsBlind injections performed in the subacromial region by experienced individuals were reliably accurate and could therefore be given in daily routines. Corticosteroid injections in the subacromial region were very effective in improving the pain and functional status of patients with subacromial impingement syndrome during the short-term follow-up.

Which questionnaire is more effective for follow-up diagnosed subacromial impingement syndrome? A comparison of the responsiveness of SDQ, SPADI and WORC index.

OBJECTIVES To compare responsiveness for the two region specific questionnaires Shoulder Disability Questionnaire (SDQ) and Shoulder Pain Disability Index (SPADI) and the disease specific Western Ontario Rotator Cuff (WORC) index in subacromial impingement syndrome (SIS) receiving physical therapy or subacromial corticosteroid injection. MATERIAL AND METHODS Sixty-four patients with SIS diagnosed participated in this study. All the patients were provided either physical therapy or subacromial corticosteroid injection treatment. The SDQ, the SPADI and WORC index were assessed both at the beginning and after the 3rd month of treatment. The responsiveness of the three questionnaires was compared by using the effect size (ES), the standardized responsiveness mean (SRM) and Guyatts method. RESULTS For both treatment groups there was no statistical difference observed between the pre- and post treatment measurement results versus improvement differences (p> 0.05). SDQ (ES=0.94; SRM=1.14; Guyatt value=0.95), SPADI (ES=1.55; SRM=2.14; Guyatt value=1.08), WORC index (ES=1.37; SRM=1.70; Guyatt value=1.15) were highly responsive for SIS. CONCLUSIONS The SDQ, the SPADI and the WORC index are suitable for measuring changes in patients with SIS. Of these three indices, the SDQ and the SPADI are more suitable for a rapid assessment whereas the WORC index is better in cases where a more detailed assessment including the psychological impact created by the functional status needs to be assessed.

Is hand bone mineral density a marker for hand function in patients with established rheumatoid arthritis? The correlation among bone mineral density of the hand, radiological findings and hand function

The objective of this study is to assess the role of hand bone mineral density (BMD) as a prospective marker for hand function and the correlation of hand BMD with X-ray findings and hand functioning in patients with established rheumatoid arthritis (RA). Eighty-three female patients diagnosed with RA were enrolled. All BMD measurements were performed on both hands. The radiological evaluation was conducted according to the van der Heijde modification of the Sharp method (Sharp/van der Heijde). Duruöz Hand Index (DHI) was used to establish the disability in the hands. Furthermore, handgrip strength (HGS), pinch strength (PS), lateral pinch (LP), tip-to-tip pinch (TTP) and three-fingered pinch (TFP) on both the dominant and the non-dominant hands was measured. A significant positive correlation between hand BMD and HGS as well as all PSs with p < 0.05 was observed, while no statistically significant relation was observed between BMD and DHI (p > 0.05). The hand BMD and the Sharp/van der Heijde scores were significantly in reverse correlation (p < 0.05). As for other DHI-related variants, HGS and PS and the total DHI scores were reversely correlated, while there was a positive significant association with radiological scores (p < 0.05). HGS and TTP were found significant (p < 0.05) as a result of a multivariant linear stepwise regression analysis among the sub-groups of DHI, HGS, LP, TTP, TFP and radiographic total scores. Our study demonstrated that a one-off hand BMD measurement failed to adequately indicate a loss in hand function as measured by DHI. Ultimately, HGS and TTP were shown to be the most effective indicators for measuring hand functions.

The relationship between hand function, depression, and the psychological impact of trauma in patients with traumatic hand injury.

The aim of this study was to investigate the acute-stage and later-stage impacts of trauma on a patient, and to determine the relationship between the degree of the impact of the event and recovery of hand function in patients with traumatic hand injury. The functional status of patients was assessed by the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire; psychological influence was assessed by the Beck Depression Inventory (BDI); and the impact of the event was assessed by the Impact of Event Scale-Revised (IES-R) both during the acute stage and at a later stage. Fifty-four patients completed the study. The DASH, BDI, and IES-R scores were significantly improved at a later stage compared with the acute stage (P<0.05). The DASH, BDI, and IES-R scores had significant positive correlations with each other in both the acute stage and later stage (P<0.05). In the linear regression analysis, the independent variables affecting the DASH score at a later stage were the DASH and IES-R scores in the acute stage (P<0.05), whereas depression scores had no effect on functional outcome (P>0.05). Our study suggests that depression status, functional status of the hand, and impact of the event improve at a later stage, and that the functional outcome at a later stage is affected by the degree of impact of the event, and the functional status of the hand in the acute stage, in patients with traumatic hand injury.

Assessment on self-care, mobility and social function of children with spina bifida in Turkey.

The aim of the study was to investigate the functional performance in children with spina bifida, using the Pediatric Evaluation of Disability Inventory (PEDI) to look into capacity of twenty-eight children with spina bifida with lesions at different levels in different dimensions of self-care, mobility and social function. Mean age of the patients was 3.5 ± 2.3 (1–10) years. In the muscle test carried out, 13 patients (44.8%) had no movements including pelvic elevation in lower extremity muscles and they were at level 5. Sixteen patients (54%) were non-ambulatory according to the Hoofer ambulation classification. Raw and scale scores in the self-care, mobility and social function domains both in the functional skill scale and in the caregiver scale were found to be lower compared to the data of the normal population. A statistically significant correlation was observed in the self-care values of the Functional Skills Scales and the Caregiver Assistance Scale measurements, which was positive for age and negative for Functional Ambulation Scale and muscle test (P < 0.05). A positive relation was found between the Functional Skills Scales-mobility area and age while a negative relation was observed between Functional Ambulation Scale and muscle test (P < 0.005). A negative relation was also found between Caregiver Assistance Scale-mobility and Functional Ambulation Scale and muscle test (P < 0.005). In our study, the functional performance of the children was found to be low. Low-level lesions, encouraging muscular strength and independence in mobility are all very important factors for functional independence.

Hand bone mineral density reference values in a Turkish healthy female population.

In this study we aimed at identifying the bone mineral density (BMD) reference values of hands, according to age, measured by dual‐energy X‐ray absorptiometry (DEXA) and assessing the correlation of these values with lumbar and femoral BMD values.

Comparison of Ultrasonography and Short-Segment Nerve Conduction Study in Ulnar Neuropathy at the Elbow

OBJECTIVE To assess the correlation between ultrasonographic and electrodiagnostic findings to determine the localization of the ulnar trapping at the elbow. DESIGN Cross-sectional and noninterventional trial. SETTING Physical medicine and rehabilitation department of a teaching hospital. PARTICIPANTS Patients (N=14) diagnosed with ulnar nerve entrapment using short-segment nerve conduction study. INTERVENTIONS The elbow area was divided into 4 segments with 2-cm intervals. All patients underwent ultrasonographic and electrodiagnostic examinations. MAIN OUTCOME MEASURES The nerve conduction velocity (NCV) of each segment was measured. The cross-sectional area (CSA) of the ulnar nerve was measured at 5 levels. The proximal CSA/distal CSA ratio (PDR) was calculated by proportioning the CSA values for each segment. The highest PDR was accepted as a trapping segment, whereas the segment with the lowest NCV was accepted electrophysiologically (provided it was <50m/s). RESULTS A total of 80 PDR and NCV measurements were taken from 20 elbows. A statistically significant negative correlation (r=-.554; P<.001) was found between general PDR and NCV values. When we assumed that the NCV value <50m/s as the criterion standard for diagnosis, the cutoff value for the PDR was found to be 1.08, with a sensitivity of 70% and a specificity of 92.5%. The minimum NCV value and the maximum PDR value were mostly seen in the third segment compatible with the cubital tunnel. CONCLUSIONS Ultrasonography seems to be advantageous because it is more comfortable for the patient and requires shorter time than does electroneuromyography. To our knowledge, this is the first study to detect ulnar nerve entrapment by using not only CSA but also PDR as a ratio method with ultrasound.

A Case with Ankylosing Spondylitis Who Developed Hodgkin Lymphoma Following Etanercept Therapy

Ankylosing Spondylitis (AS) is a chronic, systemic, and inflammatory rheumatic disease affecting primarily axial skeleton. In cases non-responsive to classical therapeutic approaches, tumor necrosis factor-α (TNF-α) antagonists have become new treatment alternatives. With anti-TNF drugs usage, rate of lymphoma development has increased especially in patients with rheumatoid arthritis. In this case-report, we report a patient with (AS) who presented with Hodgkin Lymphoma (HL) at the 3rd month of anti-TNF therapy. This complication should be remembered and close follow-up should be pursued in patients who are under immunosuppressive therapy with anti-TNF drugs, which were also used in the treatment of rheumatic diseases.

Reliability and validity of the Turkish version of the mini osteoporosis quality of life questionnaire

OBJECTIVE The purpose of this study was to develop a Turkish version of the mini Osteoporosis Quality of Life Questionnaire (mini-OQLQ), and assess its reliability and validity. MATERIAL AND METHOD Sixty-four women with postmenopausal osteoporosis were included in the study. Patients who were diagnosed with secondary osteoporosis through clinical and laboratory examinations were excluded from the study. After translation process, the Turkish version of the scale was applied to each participant twice with an interval of 2 weeks. For reliability study, internal consistency (Cronbachs α) of mini-OQLQ total score and test-retest intraclass correlation coefficient (ICC) were calculated. Validation study was assessed by correlating the scale with QUALEFFO 41. RESULTS The mean age at menopause and age of patients were 45.61 ± 6.04 and 59.91 ± 8.69 years, respectively. Cronbachs α of the Turkish version of the mini-OQLQ was 0.898. The test-retest reliability (ICC) of the Turkish version of the mini-OQLQ was determined as 0.81 for the total score, and ranged between 0.71 and 0.84 for individual items. In terms of validity, the Turkish version of mini-OQLQ showed significant negative correlation with QUALEFFO 41 (r= -0.756; p < 0.0001). CONCLUSION The Turkish version of the mini-OQLQ was found to be reliable and valid in the evaluation of life quality of patients with postmenopausal osteoporosis.

Comparison of body composition, nutritional status, functional status, and quality of life between osteoporotic and osteopenic postmenopausal women

BACKGROUND AND OBJECTIVE Osteoporosis is a condition that affects body composition, physical activity, and psychological state. We aimed to examine the differences between osteoporotic and osteopenic postmenopausal women with respect to body composition, nutrition, functional status, and quality of life. MATERIALS AND METHODS A total of 102 osteopenic (Group 1) and 100 osteoporotic (Group 2) patients were enrolled in the study. Bone mineral density (BMD), fat tissue mass (FTM), lean tissue mass (LTM), and bone mineral content (BMC) were evaluated using dual-energy X-ray absorbtiometry. Nutritional status of the patients was assessed with the Mini Nutritional Assessment (MNA), functional status with the Nottingham Extended Activities of Daily Living (NEADL) scale, and quality of life with the assessment of health-related quality of life in osteoporosis (ECOS-16). RESULTS Group 2 had significantly lower FTM, LTM, and MNA scores than Group 1 (P<0.05). NEADL and ECOS-16 scores did not differ between the groups (P>0.05). A significant correlation was found between MNA and FTM, LTM, BMC, and BMD (P<0.05). Whereas the assessment of functional status showed a significant positive correlation with BMD and a significant negative correlation with age (P<0.05), no significant correlation was found between functional status and body composition (P>0.05). CONCLUSIONS We found lower FTM and LTM values and a poorer nutritional status in osteoporotic patients than in osteopenic ones. Nutritional status was correlated with body composition and BMD, and functional status was correlated with age and BMD.