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Bernard Belleau

Shire plc

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Publication

Featured researches published by Bernard Belleau.

Bioorganic & Medicinal Chemistry Letters | 1993

A novel class of 1,3-oxathiolane nucleoside analogues having potent anti-HIV activity

Bernard Belleau; Livio Brasili; Laval Chan; Marika P. DiMarco; Boulos Zacharie; Nghe Nguyen-Ba; Helen J. Jenkinson; Jonathan Coates; Janet M. Cameron

Abstract We have developed a novel class of 1,3-oxathiolane nucleoside analogues which were evaluated for anti-HIV activity in the MT-4 cell line. BCH-371 , the adenine derivative, has been found to exhibit significant anti-HIV activity.

Antimicrobial Agents and Chemotherapy | 1991

Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog.

H. Soudeyns; Xiao-Jian Yao; Qing Gao; Bernard Belleau; J.-L. Kraus; Nghe Nguyen-Ba; B. Spira; Mark A. Wainberg

Archive | 1989

2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties

Bernard Belleau; Nghe Nguyen-Ba

Archive | 1990

Substituted 1,3-oxathiolanes with antiviral properties

Bernard Belleau; Pierette Belleau; Nghe Nguyen-Ba

Archive | 1989

2-Substituted-4-Substituted-1,3-Dioxolanes, Synthesis and use thereof

Bernard Belleau; Dilop Dixit; Nghe Nguyen-Ba

Archive | 1992

1,3-oxathiolanes useful in the treatment of hepatitis

Bernard Belleau; Nghe Nguyen-Ba

Archive | 1992

Process for preparing substituted 1,3-oxathiolanes with antiviral properties

Tarek S. Mansour; Allan H.L. Tse; Colleen A. Evans; Haolun Jin; Boulos Zacharie; Nghe Nguyen-Ba; Bernard Belleau

Archive | 2004

Acetaldehyde acetal compounds, their synthesis, and uses thereof

Dilip M. Dixit; Nghe Nguyen-Ba; Bernard Belleau

Archive | 1990

Thioacylating reagents and intermediates, thiopeptides, and methods for preparing and using same

Denis Brillon; Gilles Sauve; Boulos Zacharie; Bernard Belleau

Archive | 1992

A process for the preparation of substituted 1,3-oxathiolanes with antiviral properties

Nghe Nguyen-Ba; Tarek S. Mansour; Allan H.L. Tse; Colleen A. Evans; Haolun Jin; Boulos Zacharie; Bernard Belleau

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Collaboration

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Nghe Nguyen-Ba

University of Alberta

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Colleen A. Evans

Université du Québec

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Tarek S. Mansour

University of Ottawa

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Denis Brillon

University of Guelph

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Gilles Sauve

McGill University

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Laval Chan

University of Alberta

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Mark A. Wainberg

Jewish General Hospital

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Livio Brasili

University of Modena and Reggio Emilia

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Jonathan Coates

University of Wollongong

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Janet M. Cameron

University of Hertfordshire

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