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Dive into the research topics where Bernhard Homey is active.

Publication


Featured researches published by Bernhard Homey.


Journal of Biological Chemistry | 2000

Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2)

Wei Wang; Hortensia Soto; Elizabeth R. Oldham; Matthew E. Buchanan; Bernhard Homey; Daniel Catron; Nancy Jenkins; Neal G. Copeland; Debra J. Gilbert; Nhung Nguyen; John S. Abrams; David Kershenovich; Kathleen Smith; Terri McClanahan; Alain Vicari; Albert Zlotnik

We report the identification and characterization of a novel CC chemokine designated CCL28 and its receptor CCR10, known previously as orphan G-protein-coupled receptor GPR2. Human and mouse CCL28 share 83% identity at the amino acid and 76% at the nucleic acid levels. We also identified the mouse homologues of CCL28 and of CCR10, which map to mouse chromosomes 13 and 11, respectively. CCL28 is expressed in a variety of human and mouse tissues, and it appears to be predominantly produced by epithelial cells. Both human and mouse CCL28 induce calcium mobilization in human and mouse CCR10-expressing transfectants. CCL28 desensitized the calcium mobilization induced in CCR10 transfectants by CCL27, indicating that these chemokines share this new chemokine receptor. In vitro, recombinant human CCL28 displays chemotactic activity for resting CD4 or CD8 T cells.


Archive | 2001

Uses of mammalian genes and related reagents

Bernhard Homey; Monica L. Zepeda; Albert Zlotnik


Archive | 2000

Use of agonists or antagonists of mip-3a in therapy

Elizabeth R. Oldham; Bernhard Homey; Marie-Caroline Dieu-Nosjean; Christophe Caux; Albert Zlotnik


Archive | 2000

Method for treating inflammatory conditions using an antibody to MIP-3α

Elizabeth R. Oldham; Bernhard Homey; Marie-Caroline Dieu-Nosjean; Christophe Caux; Albert Zlotnik


Archive | 1999

Agonists or antagonists of cutaneous T cell-attracting chemokine (CTACK) or vasoactive intestinal contractor (VIC) chemokines

Wei Wang; Elizabeth R. Oldham; Hortensia Soto; Ying Lui; Susan Hudak; Bernhard Homey; Janine M. Morales; Sirid-Aimee Kellermann; Leslie M. McEvoy; Albert Zlotnik


Archive | 2001

Chemokine and receptor uses; compositions; methods

Wei Wang; Elizabeth R. Oldham; Hortensia Soto; Ying Liu; Susan Hudak; Bernhard Homey; Janine M. Morales; Sirid-Aimee Kellermann; Leslie M. McEvoy; Edward P. Bowman; Albert Zlotnik


Archive | 2013

This information is current as ExposureProducts and Allergen Cell-Derived Chemokine, Is Regulated by Dermatitis-Associated and Dendritic CC Chemokine Ligand 18, An Atopic

Bernhard Homey; Harri Alenius; Lajos Kemény; Thomas Ruzicka; Eniko Sonkoly; Wolf-Herman Fridman; Juliane Rieker; Anja Müller; Ludivine Da Cunha; Robert Kubitza; Michael Gombert


GBM Annual Fall meeting Halle 2002 | 2002

A role for Chemokine Receptors in Cancer Metastasis

Albert Zlotnik; Anja Müller; Bernhard Homey


Archive | 2001

7 transmembrane receptor family member BLRX

Joseph A. Hedrick; Bernhard Homey; Alain Vicari; Monica L. Zepeda; Albert Zlotnik


Archive | 2001

Method of impairing movement of a CLA + memeory T-cell within or to the skin of a mammal by administering a CTACK antagonist

Wei Wang; Elizabeth R. Oldham; Hortensia Soto; Ying Liu; Susan Hudak; Bernhard Homey; Janine M. Morales; Sirid-Aimee Kellermann; Leslie M. McEvoy; Edward P. Bowman; Albert Zlotnik

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