Bojan Markovic

A High-Linearity, 17 ps Precision Time-to-Digital Converter Based on a Single-Stage Vernier Delay Loop Fine Interpolation

This paper presents a time-to-digital converter (TDC) architecture capable of reaching high-precision and high-linearity with moderate area occupation per measurement channel. The architecture is based on a coarse counter and a couple of two-stage interpolators that exploit the cyclic sliding scale technique in order to improve the conversion linearity. The interpolators are based on a new coarse-fine synchronization circuit and a new single-stage Vernier delay loop fine interpolation. In a standard cost-effective 0.35 μm CMOS technology the TDC reaches a dynamic range of 160 ns, 17.2 ps precision and differential non-linearity better than 0.9% LSB rms. The TDC building block was designed in order to be easily assembled in a multi-channel monolithic TDC chip. Coupled with a SPAD photodetector it is aimed for TCSPC applications (like FLIM, FCS, FRET) and direct ToF 3-D ranging.

SPAD Smart Pixel for Time-of-Flight and Time-Correlated Single-Photon Counting Measurements

We present a smart pixel based on a single-photon avalanche diode (SPAD) for advanced time-of-flight (TOF) and time-correlated single photon counting (TCSPC) applications, fabricated in a cost-effective 0.35- m CMOS technology. The large CMOS detector (30- m active area diameter) shows very low noise (12 counts per second at room temperature at 5-V excess bias) and high efficiency in a wide wavelength range (about 50% at 410 nm and still 5% at 800 nm). The analog front-end electronics promptly senses and quenches the avalanche, thus leading to an almost negligible afterpulsing effect. The in-pixel 10-bit time-to-digital converter (TDC) provides 312-ps resolution and 320-ns full-scale range (FSR), i.e., 10-cm single-shot spatial resolution within 50-m depth range in a TOF system. The in-pixel 10-bit memory and output buffers make this smart pixel the viable building block for advanced single-photon imager arrays for 3-D depth ranging in safety and security applications and for 2-D fluorescence lifetime decays in biomedical imaging.

Low-noise and large-area CMOS SPADs with timing response free from slow tails

This paper reports the design and the characterization of Single-Photon Avalanche Diodes (SPADs) fabricated in a standard 0.35 μm CMOS technology aimed at very low noise and sharp timing response. We present the investigation on the breakdown voltage, photon detection efficiency (PDE), dark count rate (DCR) and timing response on devices with different dimensions and shapes of the active area. Results show uniform breakdown voltage among different structures, PDE above 50% at λ = 420 nm, DCR below 50 cps at room temperature and timing response with no exponential tail and typical full-width at half-maximum of 77 ps and 120 ps for 10 μm and 30 μm active areas, respectively. The fabricated devices enable the fabrication of imagers with CMOS SPAD arrays suitable for advanced applications demanding extremely low noise and picosecond timing accuracy.

16-Channel Module Based on a Monolithic Array of Single-Photon Detectors and 10-ps Time-to-Digital Converters

We present a compact and high-performance time-correlated single-photon counting detection module, based on a monolithic CMOS chip with an array of 16 channels, each composed by a 20 μm diameter single-photon avalanche diode and a time-to-digital converter. All 16 channels are independent and provide single-photon sensitivity in the visible and NIR wavelength range, from 350 to 950 nm (with a peak 45% detection efficiency at 450 nm), 10 ps photon-timing resolution, 160 ns full-scale range, better than 70 ps (full-width at half maximum) precision, and a differential non-linearity better than 0.015 LSB [root mean square (rms)], i.e., 150 fs (rms). The module requires just an USB 2.0 link for data-communication to a remote computer and power-supply, and it proves to be the best candidate for a wide variety of multichannel, low-power, compact, photon-counting, and photon-timing applications.

10 ps resolution, 160 ns full scale range and less than 1.5% differential non-linearity time-to-digital converter module for high performance timing measurements.

We present a compact high performance time-to-digital converter (TDC) module that provides 10 ps timing resolution, 160 ns dynamic range and a differential non-linearity better than 1.5% LSB(rms). The TDC can be operated either as a general-purpose time-interval measurement device, when receiving external START and STOP pulses, or in photon-timing mode, when employing the on-chip SPAD (single photon avalanche diode) detector for detecting photons and time-tagging them. The instrument precision is 15 ps(rms) (i.e., 36 ps(FWHM)) and in photon timing mode it is still better than 70 ps(FWHM). The USB link to the remote PC allows the easy setting of measurement parameters, the fast download of acquired data, and their visualization and storing via an user-friendly software interface. The module proves to be the best candidate for a wide variety of applications such as: fluorescence lifetime imaging, time-of-flight ranging measurements, time-resolved positron emission tomography, single-molecule spectroscopy, fluorescence correlation spectroscopy, diffuse optical tomography, optical time-domain reflectometry, quantum optics, etc.

X-ray imaging with ePix100a: a high-speed, high-resolution, low-noise camera

The ePix100A camera is a 0.5 megapixel (704 x 768 pixels) camera for low noise x-ray detection applications requiring high spatial and spectral resolution. The camera is built around a hybrid pixel detector consisting of 4 ePix100a ASICs ip-chip bonded to one sensor. The pixels are 50 μm x 50 μm (active sensor size ~ 35:4mm x 38:6 mm), with a noise of ~ 180 eV rms, a range of 100 8 keV photons, and a current frame rate of 240 Hz (with an upgrade path towards ~ 10 kHz). This performance leads to a camera combining a high dynamic range, high signal to noise ratio, high speed and excellent linearity and spectroscopic performance. While the ePix100A ASIC has been developed for pulsed source applications (e.g., free-electron lasers), it performs well with more common sources (e.g., x-ray tubes, synchrotron radiation). Several cameras have been produced and characterized and the results are reported here, along with x-ray imaging applications demonstrating the camera performance.

Design and characterization of the ePix10k: a high dynamic range integrating pixel ASIC for LCLS detectors

ePix10k is a variant of a novel class of integrating pixel ASICs architectures optimized for the processing of signals in second generation LINAC Coherent Light Source (LCLS) X-Ray cameras. The ASIC is optimized for high dynamic range application requiring high spatial resolution and fast frame rates. ePix ASICs are based on a common platform composed of a random access analog matrix of pixel with global shutter, fast parallel column readout, and dedicated sigma-delta analog to digital converters per column. The ePix10k variant has 100um×100um pixels arranged in a 176×192 matrix, a resolution of 140e- r.m.s. and a signal range of 3.5pC (10k photons at 8keV). In its final version it will be able to sustain a frame rate of 2kHz. A first prototype has been fabricated and characterized. Performance in terms of noise, linearity, uniformity, cross-talk, together with preliminary measurements with bump bonded sensors are reported here.

Monolithic time-to-digital converter chips for time-correlated single-photon counting and fluorescence lifetime measurements

We present a low-power Time-to-Digital Converter (TDC) chip, fabricated in a standard cost-effective 0.35 μm CMOS technology, which provides 160 ns dynamic range, 10 ps timing resolution and Differential Non-Linearity better than 0.01 LSB rms. This chip is the core of a compact TDC module equipped with an USB 2.0 interface for user-friendly control and data-acquisition. The TDC module is suitable for a wide variety of applications such as Fluorescence Lifetime Imaging (FLIM), time-resolved spectroscopy, Diffuse Optical Spectroscopy (DOS), Optical Time-Domain Reflectometry (OTDR), quantum optics, etc. In particular, we show the application of our TDC module to fluorescence lifetime measurements.

Characterization of the ePix100 prototype: a front-end ASIC for second-generation LCLS integrating hybrid pixel detectors

ePix100 is the first variant of a novel class of integrating pixel ASICs architectures optimized for the processing of signals in second generation LINAC Coherent Light Source (LCLS) X-Ray cameras. ePix100 is optimized for ultra-low noise application requiring high spatial resolution. ePix ASICs are based on a common platform composed of a random access analog matrix of pixel with global shutter, fast parallel column readout, and dedicated sigma-delta analog to digital converters per column. The ePix100 variant has 50μmx50μm pixels arranged in a 352x384 matrix, a resolution of 50e- r.m.s. and a signal range of 35fC (100 photons at 8keV). In its final version it will be able to sustain a frame rate of 1kHz. A first prototype has been fabricated and characterized and the measurement results are reported here.

Time-resolved optical spectrometer based on a monolithic array of high-precision TDCs and SPADs

We present a compact time-resolved spectrometer suitable for optical spectroscopy from 400 nm to 1 μm wavelengths. The detector consists of a monolithic array of 16 high-precision Time-to-Digital Converters (TDC) and Single-Photon Avalanche Diodes (SPAD). The instrument has 10 ps resolution and reaches 70 ps (FWHM) timing precision over a 160 ns full-scale range with a Differential Non-Linearity (DNL) better than 1.5 % LSB. The core of the spectrometer is the application-specific integrated chip composed of 16 pixels with 250 μm pitch, containing a 20 μm diameter SPAD and an independent TDC each, fabricated in a 0.35 μm CMOS technology. In front of this array a monochromator is used to focus different wavelengths into different pixels. The spectrometer has been used for fluorescence lifetime spectroscopy: 5 nm spectral resolution over an 80 nm bandwidth is achieved. Lifetime spectroscopy of Nile blue is demonstrated.