Can Jin

Eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-ones in ionic liquids or ionic liquid–water without additional catalyst

2,3-Dihydroquinazolin-4(1H)-ones have been synthesized in high to excellent yields through direct cyclocondensation of anthranilamides and aldehydes in ionic liquids (ILs) or one-pot three-component cyclocondensation of isatoic anhydrides, ammonium acetate and aldehydes in ionic liquid–water solvent system without the use of any additional catalyst.

Highly regioselective ring-opening of epoxides with thiophenols in ionic liquids without the use of any catalyst

Clean thiolysis reaction of various epoxides in ionic liquids (ILs) without the use of any catalyst generates β-hydroxy sulfides in excellent yields (83–98%) with high regioselectivity and chemoselectivity under mild reaction conditions.

Mechanically activated synthesis of 1,3,5-triaryl-2-pyrazolines by high speed ball milling

An efficient mechanically activated solvent-free synthesis of 1,3,5-triaryl-2-pyrazolines from chalcones and phenylhydrazines using high speed ball milling is described. This method has notable advantages in terms of good yield, short reaction time and neat conditions.