Carl-Magnus A. Andersson
ACADIA Pharmaceuticals Inc.
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Publication
Featured researches published by Carl-Magnus A. Andersson.
Tetrahedron Letters | 2000
Roger Olsson; Henrik C. Hansen; Carl-Magnus A. Andersson
Abstract Rapid parallel synthesis of thioamides is described. A library of amides, synthesised by mixing acyl chlorides and diamines, was transformed into the corresponding thioamides utilising Lawessons reagent as the oxygen/sulphur exchange reagent. Purification by solid-phase extraction afforded the library members in adequate purities and yields.
Tetrahedron Letters | 2001
Magnus Gustafsson; Roger Olsson; Carl-Magnus A. Andersson
Abstract A novel solid phase synthesis of tertiary amines involving iodide-induced cleavage of the N O bond of resin bound alkoxyammonium intermediates is described. The quaternary intermediates were assembled via sequential reductive aminations followed by alkylation. Cleavage from the solid support was induced by iodide ion or base, to afford the target tertiary amines in excellent purity.
Bioorganic & Medicinal Chemistry Letters | 2000
Henrik C. Hansen; Roger Olsson; Glenn Croston; Carl-Magnus A. Andersson
A flexible, multistep parallel synthesis of spiperone analogues is described. A library of 4-substituted piperidines, assembled utilizing reductive amination and acylation protocols, was alkylated either homogeneously or heterogeneously, exploiting a product release only concept, to afford an oxa-series of spiperone analogues. Screening of the products at 5-HT2 and D2 receptors revealed 5-HT2A antagonists with improved selectivity compared to spiperone and AMI-193.
Archive | 2004
David M. Weiner; Robert E. Davis; Mark R. Brann; Carl-Magnus A. Andersson; Allan K. Uldam
Archive | 2003
Carl-Magnus A. Andersson; Nathalie Schlienger; Alma Fejzic; Eva Louise Hansen; Jan Pawlas
Archive | 2001
Carl-Magnus A. Andersson; Glenn Croston; Eva-Louise Hansen; Allan K. Uldam
Archive | 2005
Mikkel Boas Thygesen; Nathalie Schlienger; Bo-Ragnar Tolf; Carl-Magnus A. Andersson; Fritz Blatter; Jörg Berghausen
Archive | 2008
Mikkel Boas Thygesen; Nathalie Schlienger; Bo-Ragnar Tolf; Carl-Magnus A. Andersson; Fritz Blatter; Jörg Berghausen
Archive | 2000
Carl-Magnus A. Andersson; Magnus Gustafsson; Kent R. I. Olsson
Archive | 2011
Carl-Magnus A. Andersson; Glenn Croston; Eva Louise Hansen; Allan K. Uldam