Carlos Linares-López

Aortic mineralisation in children with congenital cardiac disease

BACKGROUND Congenital cardiac diseases are the most frequent congenital malformations. In adult patients, the mineralisation of the aorta due to cardiovascular disease is very common, but vascular mineralisation in paediatric cardiopathies is a topic less studied. This study shows that children with a complex congenital cardiopathy show a high degree of vascular mineralisation in the ascending aorta. This can be part of the cardiac failure pathophysiology due to congenital cardiopathies. OBJECTIVE The aim of this study was to determine the presence and degree of vascular mineralisation in samples of the ascending and descending aorta of children with complex congenital cardiopathies. DESIGN We conducted a cross-sectional study. SUBJECTS We obtained 34 vascular tissues from the autopsies of 17 children with congenital cardiac disease. METHODS We used a scanning electron microscope with an energy-dispersive X-ray spectroscopy in order to analyse the vascular tissues. RESULTS The amount of minerals was two times higher in the ascending aorta than in the descending aorta of children with congenital cardiac disease. CONCLUSIONS The study provides evidence that vascular mineralisation can start at an early age, and that it is higher in the ascending aorta than in the descending aorta.

Ca‐poor Pyroxene Raman Characteristics in H Ordinary Chondrites

In this work we present the zoning of the Ca‐poor pyroxenes polymorphs and its Raman characteristics of crystal within chondrules in H3.3, H4, H5 and H6 ordinary chondrite suite. Applying the Principal Component Analysis (PCA) method to the Raman data and plotting the first and second principal components, we were able to differentiate their petrologic types in four separate fields.