Catherine A. Pipenhagen
St. Jude Medical
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Publication
Featured researches published by Catherine A. Pipenhagen.
International Journal of Cardiology | 2017
Felix Mahfoud; Catherine A. Pipenhagen; L. Boyce Moon; Sebastian Ewen; Saarraaken Kulenthiran; Jeffrey M. Fish; James A. Jensen; Renu Virmani; Michael Joner; Kazuyuki Yahagi; Costas Tsioufis; Michael Böhm
OBJECTIVES Anatomic placement of lesions may impact efficacy of radio-frequency (RF) catheter renal denervation (RDN). However, it is unclear if it is necessary to perform treatments post bifurcation with systems that may provide deeper penetration to achieve successful RDN. METHODS Sixteen domestic swine (n=16) were randomly assigned to 4 groups: 1) 8 lesions created in the branch arteries using the Spyral catheter (SP8); 2) 8 lesions created in the branch arteries plus 4 lesions created in the main artery using the SP catheter (SP12); 3) 8 lesions created in the main artery using the EnligHTN catheter with the distal position as close as possible to the bifurcation (EN8); and 4) 12 lesions created in the main artery using the EN catheter with the distal position as close as possible to the bifurcation (EN12). RESULTS Each arm showed statistically significant changes in kidney norepinephrine (NE, ng/g) between treated kidneys vs. untreated contralateral control. There were no statistically significant differences in tissue NE% reductions across each arm based on catheter, anatomic location, & number of lesions (p=0.563): EN8 -74±34%, EN12 -95±3%, SP8 -76±16%, SP12 -82±17% (p=0.496). A total of 46 lesions were measured for lesion depth: EN main (3.3±2.8mm) vs. SP branch (2.0±1.0mm, p=0.039), SP main (2.9±1.6mm) vs. SP branch (p=0.052), and EN main vs. SP main (p=0.337). CONCLUSIONS Distally-focused main renal artery treatment using the EN system appears to be equally efficacious in reducing tissue NE levels compared with SP treatment in the branches plus main renal arteries, advocating for device-specific procedure execution.
Archive | 2003
Kedar Ravindra Belhe; John Avi Roop; Catherine A. Pipenhagen
Archive | 2004
Catherine A. Pipenhagen; Kedar Ravindra Belhe; John Avi Roop
Archive | 2005
John Avi Roop; Kedar Ravindra Belhe; Catherine A. Pipenhagen
Archive | 2003
John Avi Roop; Kedar Ravindra Belhe; Catherine A. Pipenhagen
Archive | 2008
Catherine A. Pipenhagen; Melissa K. Gardner; Jyue Boon Lim; William Fiehler; Gary James Schorr; Janet L. Jacobsen
Archive | 2006
Raimar Boehlke; Kedar Ravindra Belhe; Catherine A. Pipenhagen
Archive | 2005
Catherine A. Pipenhagen; John Avi Roop; Kedar Ravindra Belhe
Archive | 2007
Catherine A. Pipenhagen; Melissa K. Gardner; William Fiehler; Janet L. Jacobsen; Gary James Schorr; Jyue Boon Lim
Archive | 2006
Kedar Ravindra Belhe; Michelle Boucha-Rayle; Catherine A. Pipenhagen