Catherine Brennan
Bayer
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Publication
Featured researches published by Catherine Brennan.
Bioorganic & Medicinal Chemistry Letters | 2000
Jacques Dumas; Holia Hatoum-Mokdad; Robert Sibley; Bernd Riedl; William J. Scott; Mary Katherine Monahan; Timothy B. Lowinger; Catherine Brennan; Reina Natero; Tiffany Turner; Jeffrey S Johnson; Robert W. Schoenleber; Ajay Bhargava; Scott Wilhelm; Timothy J Housley; Gerald Ranges; Alka Shrikhande
Inhibitors of the MAP kinase p38 are potentially useful for the treatment of arthritis and osteoporosis. Several 2,3-dichlorophenyl ureas were identified as small-molecule inhibitors of p38 by a combinatorial chemistry effort. Optimization for cellular potency led to the discovery of a new class of potent and selective p38 kinase inhibitors, exemplified by the 1-phenyl-5-pyrazolyl urea 7 (IC50 = 13 nM).
Archive | 1998
Scott Miller; Martin Osterhout; Jacques Dumas; Uday Khire; Timothy B. Lowinger; William J. Scott; Roger A. Smith; Jill E. Wood; David E. Gunn; Holia Hatoum-Mokdad; Marell Rodriguez; Robert Sibley; Ming Wang; Tiffany Turner; Catherine Brennan
Archive | 1998
Scott Miller; Martin Osterhout; Jacques Dumas; Uday Khire; Timothy B. Lowinger; Bernd Riedl; William J. Scott; Roger A. Smith; Jill E. Wood; David E. Gunn; Ming Wang; Tiffany Turner; Catherine Brennan
Archive | 2002
Julie Dixon; William J. Scott; Jacques Dumas; Catherine Brennan; Holia Hatoum-Mokdad
Archive | 2003
Jill E. Wood; Donald Bierer; Brian Bear; Catherine Brennan; Brent Chandler; Gang Chen; Yuanwei Chen; Julie Dixon; Wenlang Fu; Leatte Guernon; Donglei Liu; Andrea Mcclure; Karl Miranda; Dhanapalan Nagarathnam; Robert Sibley; Michael Robert Turner; Sharad Verma; Chunguang Wang; Lin Yi; Jin Zhao; Qingming Zhu
Archive | 2001
Jill E. Wood; Jeremy L. Baryza; Catherine Brennan; Soongyu Choi; James H. Cook; Brian R. Dixon; Paul Ehrlich; David Gunn; Ian McAlexander; Derek Lowe; Aniko Redman; William J. Scott; Yamin Wang
Archive | 2002
Jacques Dumas; Robert Sibley; Roger A. Smith; Ning Su; Yuanwei Chen; Jill E. Wood; Leatte Guernon; Julie Dixon; Catherine Brennan; Stephen Boyer
Archive | 1999
Brian R. Dixon; Cedo M. Bagi; Catherine Brennan; David R. Brittelli; William H. Bullock; Jinshan Chen; William L. Collibee; Robert Dally; Jeffrey Johnson; Harold C. E. Kluender; William F. Lathrop; Carol Ann Mase; Aniko Redman; William J. Scott; Klaus Urbahns; Donald John Wolanin
Archive | 2005
Julie A. Dixon; Catherine Brennan; Karl Miranda; Brent Chandler; Barton Phillips; Jianmei Fan; Michael Brands; Andrea Mcclure; Benjamin Jones; Wenlang Fu; Donald Bierer; Steven Magnuson; Harold C. E. Kluender
Tetrahedron Letters | 2005
James H. Cook; Jeremy Barzya; Catherine Brennan; Derek Lowe; Yamin Wang; Aniko Redman; William J. Scott; Jill E. Wood