Cenk Yardimci

Evaluation of bee venom and hyaluronic acid in the intra-articular treatment of osteoarthritis in an experimental rabbit model.

The aim of this study was to investigate bee venom and hyaluronic acid in the intra-articular treatment of osteoarthritis in an experimental rabbit model. Forty-five rabbits were used and they were randomly divided into three groups (BVI, BVII, and HA) and each group was divided to two subgroups to evaluate the radiologic, magnetic resonance imaging, histopathologic, and biochemical evaluation in post treatment second week (a) and twelfth week (b). Radiologically, a significant difference was observed in the HA group (P<0.05). The MRI evaluation of at any time in group BVI(b) was found to be different. No significant differences were seen between the groups, biochemically. Histopathologically, cellularity, and orthochromasia was evident with Safranin-O in the BVI(b) and BVII(a); adhesions were seen in the BVII(a) group and clustering of chondrocyte in the HA(b) group were found to be different. Consequently, intra-articular application of HA and BV for experimental model of osteoarthritis has no significant influence upon recovery after therapy.

Lingual Arch Bar Application for Treatment of Rostral Mandibular Body Fractures in Cats

OBJECTIVE To describe a lingual arch bar technique for fixation of rostral mandibular body fractures and report outcome in 16 cats. STUDY DESIGN Original study. ANIMALS Cats (n=16) with rostral mandibular body fracture (10 bilateral, 6 unilateral) just caudal to the canine teeth. METHODS Orthodontic wire (Dentaurum® ; 0.9 mm) was used as a lingual arch bar by contouring it to the shape of the lingual side of the alveolar margin, and secured by circum-mandibular wires passed interproximal to teeth. Stability of fixation, occlusion, tolerance to the lingual arch bar, degree of secondary gingivitis/periodontitis, and ability to eat were evaluated clinically, and fracture union was assessed radiographically. RESULTS The lingual arch bar was well tolerated. Eleven cats without a feeding tube were able to eat within 24 hours. Time to fracture union and appliance removal ranged from 28 to 64 days (mean, 42.5 days). Malocclusion of the rostral part of the fracture occurred in 5 cats; however only 1 required correction. CONCLUSIONS Intraoral stabilization of rostral mandibular fractures using a lingual arch bar is a simple and effective method for the treatment of rostral mandibular fractures just caudal to the canine teeth.

Treatment of unilateral congenital flexural and torsional limb deformities with circular external skeletal fixation system in two calves

CASE DESCRIPTION Two calves with unilateral congenital flexural and torsional limb deformities below the hock joint of the left hindlimb were presented to Veterinary Teaching Hospital of the Ondokuz Mayis University. According to clinical, goniometric and radiological examinations, flexural (130°-40°) and torsional (90°-180°) deformities were diagnosed. Except for the limb deformities, both animals were otherwise completely healthy. TREATMENT AND OUTCOME In case 1, hock joint arthrodesis was performed using a circular external skeletal fixation system with four full rings 160 mm in diameter. In case 2, the deformity was corrected by fixation after transverse osteotomy at the level of the proximal metatarsals with four full rings 150 mm in diameter, and arthrodesis of the fetlock joint with three full rings 100 mm in diameter. According to clinical examinations and follow-up telephone interviews performed 15 and 24 weeks after discharge, functional use with slight lameness in case 1 and full functional use in case 2 had been achieved. CLINICAL RELEVANCE None of the previously reported cases of flexural deformity had radiographic signs similar to those of the calves in our report, and the deformities were not as severe as those reported here. To our knowledge, this is the first report of treatment of unilateral congenital flexural and torsional deformities in calves with a circular external skeletal fixation system.

Management of traumatic tarsal luxations with transarticular external fixation in cats

OBJECTIVE To report our experience with the use of contoured mini circular transarticular external skeletal fixators for the management of traumatic tarsal luxations in 15 cats. MATERIALS AND METHODS Fifteen cats with traumatic tarsal joint luxation treated by using mini circular transarticular external fixators with available clinical records and complete clinical and radiographic follow-up of at least 30 weeks duration were included in the study. Data collected were the signalment, history, type of injury, concomitant injury, frame configuration, stabilization technique, duration of the surgery, time to first use of the operated limb, fixator removal time, complications, final outcome and follow-up. RESULTS The surgical procedure chosen was based on the type of luxation; partial tarsal arthrodesis was performed in 10 cases, tarso-crural stabilization in four cases, and pantarsal arthrodesis in three cases. Five cats started to use the operated limb immediately after recovering from anaesthesia. In the other 10 cats, time to first use ranged from one to four days (mean 2 days). In one case, early pin loosening due to half pin fixation bolt failure was observed as a postoperative complication. Fixator removal time ranged from 24 to 60 days (mean 45 days). Functional outcome was excellent in 15 cats and good in two. CLINICAL RELEVANCE This is a preliminary report about the treatment of tarsal luxations with a mini circular transarticular external fixation system in which early postoperative and long-term results seem to be favourable.

Effects of electromagnetic field (1.8/0.9 GHz) exposure on growth plate in growing rats

The purpose of this study was to determine the effects of whole-body electromagnetic field (EMF) exposure on growth plates in growing male rats. Two groups of rats were exposed to either 900 MHz EMF or 1800 MHz EMF 2 h/day for 90 days. Sham control rats were kept under similar conditions without exposure to the EMF. The rats in the EMF group experienced a more rapid weight gain and increase in length (p < 0.05). Calcium, growth hormone, estradiol and testosterone levels in the EMF groups were higher (p < 0.05). The Safranin O staining density of femoral growth plate was lowest in the reserve zone of rats exposed to 1800 MHz and was increased in the proliferative zone of the control group (p < 0.05). The trabecular zone was thinnest among all zones and the reserve and proliferative zones were thicker (p < 0.05) than other zones in 1800 MHz group.In conclusion, 1800 MHz and 900 MHz EMF may cause prolong the growth phase in growing rats.

Correction of severe congenital flexural carpal deformities with semicircular external skeletal fixation system in calves

OBJECTIVE To present a novel technique for the treatment of severe congenital flexural forelimb deformities in calves. METHODS Thirteen calves of different breeds and sex with severe congenital flexural forelimb deformities were enrolled in the study. A semicircular external skeletal fixation system composed of 6-hole, 45° carbon-fiber arches, 6 mm threaded rods, half-pin fixation bolts, 6 mm hexagonal nuts, and negative profile end-threaded half-pins were used for pancarpal arthrodesis. Complications, time to first use of the limb, fixator removal time, preoperative and postoperative sagittal plane angles of the fused joints, and functional outcomes were evaluated clinically and radiographically. Final assessments were determined according to functional and cosmetic outcomes. RESULTS All of the surgically treated carpal joints obtained fusion. Seven of the calves started to use the limb immediately after recovering from anesthesia. In the other six calves, the time ranged from one to two days. Time to fixator removal ranged from 25 to 36 days (mean 30 days). Final outcome was excellent in 11 cases, and good in two cases. CLINICAL SIGNIFICANCE The technique was found to be a useful method for the treatment of severe congenital flexural forelimb deformities in calves. The cost of the operation is negligible compared to the economic value of beef cattle.

Management of Femoral Fractures in Dogs with Unilateral Semicircular External Skeletal Fixators

OBJECTIVE To report use of semicircular external skeletal fixators (ESF) for management of femoral fractures in dogs. STUDY DESIGN Prospective clinical study. ANIMALS Dogs (n=16) with femoral fractures (n=18). METHODS A semicircular ESF system composed of 6-hole 45° or 5-hole 40° carbon-fiber arches, 6 mm threaded rods, half pin fixation bolts, 6 mm nuts, and negative profile end-threaded half pins were used for open repair of femoral fractures. ESF configuration, complications, limb use, fixator removal time, and functional outcomes were evaluated. Outcome was graded as excellent, good, fair, or poor. RESULTS Seventeen fractures with sufficient follow-up healed. Eight dogs started using the limb immediately after waking up from anesthesia whereas initial limb use was 1-4 days after repair in the other dogs. Time to fixator removal ranged from 28 to 63 days (mean, 38 days). Functional outcome was excellent in 13 cases, good in 4, and poor in 1 nonunion. CONCLUSION Semicircular ESF combined with open surgical reduction can be used to successfully repair metaphyseal and diaphyseal femoral fractures in young growing dogs.