César D. Villarreal-Villarreal

Cost Structure and Clinical Outcome of a Stem Cell Transplantation Program in a Developing Country: The Experience in Northeast Mexico

BACKGROUND AND OBJECTIVE Hematopoietic stem cell transplantation (HSCT) in developing countries is cost-limited. Our primary goal was to determine the cost structure for the HSCT program model developed over the last decade at our public university hospital and to assess its clinical outcomes. MATERIALS AND METHODS Adults and children receiving an allogeneic hematopoietic stem cell transplant from January 2010 to February 2011 at our hematology regional reference center were included. Laboratory tests, medical procedures, chemotherapy drugs, other drugs, and hospitalization costs were scrutinized to calculate the total cost for each patient and the median cost for the procedure. Data regarding clinical evolution were incorporated into the analysis. Physician fees are not charged at the institution and therefore were not included. RESULTS Fifty patients were evaluated over a 1-year period. The total estimated cost for an allogeneic HSCT was

Assessment of immune reconstitution status in recipients of a successful hematopoietic stem cell transplant from peripheral blood after reduced intensity conditioning.

12,504. The two most expensive diseases to allograft were non-Hodgkin lymphoma (

Increased Bacterial Infections after Transfusion of Leukoreduced Non-Irradiated Blood Products in Recipients of Allogeneic Stem Cell Transplants after Reduced-Intensity Conditioning

11,760 ±

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2,236) for the malignant group and thalassemia (

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12,915 ±

Polymorphic Erythematous Macules and Plaques With Dysesthesia

5,170) for the nonmalignant group. Acute lymphoblastic leukemia (

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11,053 ± 2,817) and acute myeloblastic leukemia (

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10,251 ±

Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq

1,538) were the most frequent indications for HSCT, with 11 cases each. Median out-of-pocket expenses were

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1,605, and 1-year follow-up costs amounted to