Çetin Kasapoğlu

Oral and maxillofacial considerations in Gardner's Syndrome.

Gardners Syndrome is a variant of familial adenomatosis polyposis (FAP) with a triad consisting of polyps of the colon, multiple osteomas and surface tumors of soft and hard tissue. The intestinal polyps have a %100 risk of undergoing malignant transformation, therefore early identification of this disease is very important. There are several symptoms of Gardners syndrome in the oral and maxillofacial surgery, which can be discovered during routine dental examination. We report a case of a 25-year old male patient with Gardners syndrome who has not any intestinal polyps but osteomas in the mandible and jaw deformalities.

Pleomorphic adenoma of the palate.

Pleomorphic adenoma is the most common mixed benign tumor of major salivary glands. Approximately 80% of these tumors arise in the parotid gland, whereas 7% arise in the minor salivary glands. The most common sites for minor salivary gland where pleomorphic adenoma arises are the palates followed by lips and cheek. We report a palate mass in a 46-year-old male patient. The initial cytologic diagnosis by fine-needle aspiration biopsy was pleomorphic adenoma. This report describes a case of pleomorphic adenoma regarding all distinctive diagnoses with the review of the literature.

In Vitro Antifungal Activity of Ankaferd Blood Stopper Against Candida albicans

BACKGROUND Candida albicans is a memeber of the oral flora that can lead to various complications in immunosupresive patients after oral surgery processes. Ankaferd Blood Stopper® (ABS) is a medical plant extract that is safe to use in patients with dental surgery bleedings in Turkey. OBJECTIVE The study evaluated the antifungal activity of ABS medicinal plant extract against C albicans using the agar diffusion and broth microdilution methods. METHODS The plant extract antifungal activity was assessed in vitro either by applying the ABS extract directly and by applying different concentrations of ABS onto Candida culture. For these experiments, an agar diffusion method was used. To determine the minimum inhibitory concentration (MIC), a broth microdilution method was used. RESULTS Different volumes of the active substance (10, 20, 30, and 40 μL) were applied onto Candida (0.5 McFarland solution) cultivated plate; Candida growth was inhibited in accordance with the volumes of ABS. However, when various dilutions of ABS (1:2, 1:20, 1:40, and 1:80) were added as drops containing 20 μL, no antifungal effects were found. No MIC values were identified using broth microdilution. When different dilutions of ABS containing 100 μL of 0.5 McFarland solution of C albicans were cultured depending on the time (10, 20, 30, and 40 minutes), the effect of the duration was not significant. CONCLUSION The various tests were carried out to investigate antifungal effects of ABS on Candida, but none were found.

Effects of polymethylmethacrylate on the stability of screw fixation in mandibular angle fractures: A study on sheep mandibles

Aim: Malfixed miniplates can impair fracture healing, and the screw pilot holes may widen during repeated fixation trials. This in vitro study explored the extent to which screw fixation of mandibular angle fractures could be improved by augmenting the drilling holes with polymethylmethacrylate (PMMA). Materials and Methods: We measured stabilization by recording specimen displacement under a vertical force of 50 N applied using a hydraulic tester. We included 20 hemimandibles from sheep (average weight 40 kg). The specimens were randomly divided into two groups of 10 and pilot holes were created in the angulus region using a drill 1.2 mm in diameter. Next, we performed osteotomies simulating angulus fracture repair. In group 1, the fracture site was fixed using non-compression miniplates and four screws were inserted to the maximal possible extent employing a mechanical screwdriver. In group 2, the pilot drill holes were filled with PMMA prior to miniplate fixation. Then vertical forces of 50 N were applied to the molar region and the displacements were measured. The Shapiro-Wilks test was used to compare the two groups. Result: The maximum average displacement in the experimental group was significantly lower than that in the control group (p=0.026). Thus, PMMA-augmented screws better stabilized bone, affording reliable fixation.

GENİŞ KEMİK DEFEKTİ OLAN KR ETLERİ) E KEMİK İÇİ İMPIANTLARIN YÖNLENDİRİLMİŞ DOKU REJENERASYONU MEMBRANI VE Bİ O MATERYAL İLEBİRLİKTE KULLANIMI (Olgu Bildirimi)

Ozet Implant yerlestirilmesi dusunulen bolgelerdeki yeterli kemik kalinligi ust yapi protezlerinin uzun omurlu olmasini saglayan en onemli faktordur. Bu ilkeden hareket eden implant ekibi radyolojik teshis safhasinda genellikle kemik defekti ve rezorbisyonunim hic olmadigi bolgeleri secmek yolunda hareket ederler. Ancak bazi vakalarda lokal kemik def ektlerinin oldugu bolgelerde yonlendirilmis doku regenerasyonu (GTR) membranlari kullanilarak kemik hacminin arttirilmasi ve defektli kismin regenere edilmesi yoluna gidilir. Bu sekilde, implant yerlestirmeye uygun kemik hacmi ve osseointegrasyon icin uygun spongioz kemik elde edilir. GTR teknigi ismi verilen bu metotta iki tur membran kullanilir: 1 - Rezorhe olmayan GTR membranlari, 2 - Rezorbe olabilen GTR membranlari. Rezorbe olabilen GTR membranlarmin avantaji yerlestirilen membranm regenerasyon bittikten sonra yeniden cikarilmasina ihtiyac olmamasidir. Sundugumuz bu olguda implant uygulamaya karar verdigimiz lokal kemik defekti bulunan bolgeye tam rezorbe olabilen GTR membranlarmin yerlestirildigi seansta implanti da yerlestirmeyi amacladik. Biofix GTR membrani ile Bone Fit implanti tek operasyonda kombine olarak kullanildi. 6 aylik regenerasyon suresinin bitiminde kemigin hacimsal olarak buyume gosterdigi, implant osseointegrasyonunun da tamamlandii Bazi vakalarda, kemik defekti olan bolgeye Bioftx GTR membrani-biocoral biomateryali ve Bone Fit implanti futturu tek bir operasyonla yerlestirildi. 6 aylik iyilesme periyodunun sonunda alman radyografilerde, kemik defektinin regenere oldugu, bu bolgedeki kemik hacminin yeterince buyudugu, implant futurunun osseointegrasyonunun da ayni zamanda tamamlandigi radyografik olarak tesbit edildi, ayni yontem kullanilarak yapilan 7 vakanin 3 tanesi 3 yillik, 4 tanesi 1 yillik takip surecindedir. Anahtar sozcukler: Kemik rejenerasyonu, rezorbe olabilen GTR-membranlari THE USE OF ENDOSSEOUSIMPIANTS WITH GTR MEMBRANE AND BIOMA TERIAL FOR CREST WHICH HAVE LARGE BONE DEFECTS (A case report) Abstract In some cases, where local bone defects are present the volume oftJie bone con be improved and tfie defect area can be regenerated by the use of GTR membranes. By this method the tight volume and the rigfit quality of bone can be obtained. For die GTR technique, two kinds of membranes can be utilized: 1 - Non-resorbable GTR membranes, 2 -Resorbable GTR membranes. In our cases, Hie implant fixtures were placed at the same visit together with resorbable GTR membranes to the defect areas. In 4 cases, Biqfix GTR membrane and Bone fit implants were used in combination during the sae surgery visit. At the and of 6 months regeneration period, it was observed radiographically that the bone improved volumetrically and osseointegration of the implant Key words: Bone regeneration, resorbable GTR membranes. vas completed. In 3 cases, Biofix GTR membrane, Biocoral btomaterial and Bo-nefit implant fixtures were placed at the same visit to the defect area. At tiie end of the 6 months period, it was seen radiographically die defect was regenerated, the volume of the bone was satisfactory and the osseointegration of the implant-fixture was complated. radiograf I k olarak tesbit edildi.