Chang-Kyo Shin

Synthesis of Optically Pure Terminal Epoxide and 1,2‐Diol via Hydrolytic Kinetic Resolution Catalyzed by New Heterometallic Salen Complexes

Abstract The inactive chiral (salen)Co complex is easily activated by InCl3 and TlCl3 Lewis acids by forming heterometallic salen complexes. These complexes show very high catalytic activity for the synthesis of enantiomerically enriched terminal epoxides (>99% ee) and 1,2‐diols simultaneously via hydrolytic kinetic resolution. Strong synergistic effects of different Lewis acids, Co‐In and Co‐Tl, were exhibited in the catalytic process. The system described is very simple and efficient.

Simultaneous separation and enantioselective hydrolysis reaction of epoxides in membrane system containing chiral polymer salen catalyst immobilized on MCM-41

Very high yield of optically pure epichlorohydrin (ECH) was obtained enantioselectively in the catalytic membrane system having chiral polymer salen complexes, due to simultaneous separation of the product during the reaction. The hydrophobic epoxide product diffuses across the membrane into the organic solvent phase.

Chiral (salen) cobalt complexes encapsulated in mesoporous mordenite as an enantioselective catalyst for phenolic ring opening of terminal epoxides

Phenolic ring opening of epoxides was performed successfully by using chiral (salen) Co(III) caralysts encapsuled in mesoporous mordenite.

Synthesis of optically active monoesters via enantioselective reaction catalyzed by hetero-metallic chiral (salen) Co complex immobilized on acid sites of Al-MCM-41

The new heterogeneous dinuclear chiral (salen)Co-GaCl 3 catalyst immobilized on Al-MCM-41 showed high activity for the enantioselective ring opening of terminal epoxides with carboxylic acids. Various chiral monoester derivatives could be synthesized with relatively high enantioselectivity.

Catalytic activity of dinuclear chiral salen complexes immobilized on modified SBA-15

The new heterogeneous dinuclear chiral (salen) Co-GaCl 3 catalyst immobilized on modified SBA-15 showed high activity for the enantioselective kinetic resolution of terminal epoxides with H 2 O. The heterogeneous catalysts can offer practical advantages of the facile separation from reactants and products, as well as recovery and reuse.

New Synthesis of Optically Active (L)-Alaninol over Palladium Supported Catalysts

Pd metals immobilized on SBA-15 and NaY were applied as catalysts in the synthesis of amino alcohol. These catalysts afford a high level of enantioselectivity in the asymmetric hydrogenation of α-keto alcohol to corresponding amino alcohol. The large palladium metal exhibited higher catalytic activity and enantioselectivity than well dispersed one over porous supports in the hydrogenation.