Charlie Loke

Immunology of placentation in eutherian mammals

The traditional way to study the immunology of pregnancy follows the classical transplantation model, which views the fetus as an allograft. A more recent approach, which is the subject of this Review, focuses on the unique, local uterine immune response to the implanting placenta. This approach requires knowledge of placental structure and its variations in different species, as this greatly affects the type of immune response that is generated by the mother. At the implantation site, cells from the mother and the fetus intermingle during pregnancy. Unravelling what happens here is crucial to our understanding of why some human pregnancies are successful whereas others are not.

Biology and Pathology of Trophoblast

Preface Charlie Loke Chairs introduction Anne McLaren 1. Trophoblast cell fate specification: discussion James Cross 2. Stem cells: pluripotency and extraembryonic differentiation in the mouse Tilo Kunath 3. Epigenetic regulation of trophoblast development P. Hajkova, S. E. Erhardt and M. A. Surani 4. Regulation of X chromosome inactivation in relation to lineage allocation in early mouse embryogenesis Neil Brockdorff 5. Gestational Trophoblastic disease R. A. Fisher and N. J. Sebire 6. Trophoblast and the first trimester environment Graham J. Burton, Eric Jauniaux 7. Implantation is a sticky situation Olga Genbacev, Akraporn Prakobphol, Russell A. Foulk and Susan J. Fisher 8. Trophoblast regulation of maternal endocrine function and behaviour E. B. Keverne 9. Molecular signalling in embryo-uterine interactions during implantation S. K. Dey and Susanne Tranguch 10.Trophoblast and pre-eclampsia C. W. G. Redman, I. L. Sargent and E. A. Linton 11. Trophoblast and uterine mucosal leukocytes Ashley Moffett 12. Immunology of trophoblast: a reappraisal Charlie Loke.

Biology and Pathology of Trophoblast: Contents

Preface Charlie Loke Chairs introduction Anne McLaren 1. Trophoblast cell fate specification: discussion James Cross 2. Stem cells: pluripotency and extraembryonic differentiation in the mouse Tilo Kunath 3. Epigenetic regulation of trophoblast development P. Hajkova, S. E. Erhardt and M. A. Surani 4. Regulation of X chromosome inactivation in relation to lineage allocation in early mouse embryogenesis Neil Brockdorff 5. Gestational Trophoblastic disease R. A. Fisher and N. J. Sebire 6. Trophoblast and the first trimester environment Graham J. Burton, Eric Jauniaux 7. Implantation is a sticky situation Olga Genbacev, Akraporn Prakobphol, Russell A. Foulk and Susan J. Fisher 8. Trophoblast regulation of maternal endocrine function and behaviour E. B. Keverne 9. Molecular signalling in embryo-uterine interactions during implantation S. K. Dey and Susanne Tranguch 10.Trophoblast and pre-eclampsia C. W. G. Redman, I. L. Sargent and E. A. Linton 11. Trophoblast and uterine mucosal leukocytes Ashley Moffett 12. Immunology of trophoblast: a reappraisal Charlie Loke.

Biology and Pathology of Trophoblast: Index

Preface Charlie Loke Chairs introduction Anne McLaren 1. Trophoblast cell fate specification: discussion James Cross 2. Stem cells: pluripotency and extraembryonic differentiation in the mouse Tilo Kunath 3. Epigenetic regulation of trophoblast development P. Hajkova, S. E. Erhardt and M. A. Surani 4. Regulation of X chromosome inactivation in relation to lineage allocation in early mouse embryogenesis Neil Brockdorff 5. Gestational Trophoblastic disease R. A. Fisher and N. J. Sebire 6. Trophoblast and the first trimester environment Graham J. Burton, Eric Jauniaux 7. Implantation is a sticky situation Olga Genbacev, Akraporn Prakobphol, Russell A. Foulk and Susan J. Fisher 8. Trophoblast regulation of maternal endocrine function and behaviour E. B. Keverne 9. Molecular signalling in embryo-uterine interactions during implantation S. K. Dey and Susanne Tranguch 10.Trophoblast and pre-eclampsia C. W. G. Redman, I. L. Sargent and E. A. Linton 11. Trophoblast and uterine mucosal leukocytes Ashley Moffett 12. Immunology of trophoblast: a reappraisal Charlie Loke.

Biology and Pathology of Trophoblast: Biology and Pathology of Trophoblast

Preface Charlie Loke Chairs introduction Anne McLaren 1. Trophoblast cell fate specification: discussion James Cross 2. Stem cells: pluripotency and extraembryonic differentiation in the mouse Tilo Kunath 3. Epigenetic regulation of trophoblast development P. Hajkova, S. E. Erhardt and M. A. Surani 4. Regulation of X chromosome inactivation in relation to lineage allocation in early mouse embryogenesis Neil Brockdorff 5. Gestational Trophoblastic disease R. A. Fisher and N. J. Sebire 6. Trophoblast and the first trimester environment Graham J. Burton, Eric Jauniaux 7. Implantation is a sticky situation Olga Genbacev, Akraporn Prakobphol, Russell A. Foulk and Susan J. Fisher 8. Trophoblast regulation of maternal endocrine function and behaviour E. B. Keverne 9. Molecular signalling in embryo-uterine interactions during implantation S. K. Dey and Susanne Tranguch 10.Trophoblast and pre-eclampsia C. W. G. Redman, I. L. Sargent and E. A. Linton 11. Trophoblast and uterine mucosal leukocytes Ashley Moffett 12. Immunology of trophoblast: a reappraisal Charlie Loke.