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Dive into the research topics where Chen Ba is active.

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Featured researches published by Chen Ba.


Leukemia Research | 2010

Role of the TNF-α promoter polymorphisms for development of multiple myeloma and clinical outcome in thalidomide plus dexamethasone

Juan Du; Zhengang Yuan; Chunyang Zhang; Weijun Fu; Hua Jiang; Chen Ba; Jian Hou

The role of TNF-α promoter polymorphisms in the development of multiple myeloma (MM) were tested in 210 patients and 218 healthy individuals and their impact on the clinical outcome were evaluated in 98 patients treated with thalidomide and dexamethasone (Thal+Dex) regimen. MM patients carrying the GA genotype (P=0.01) or GA+AA genotypes (P=0.02) at the TNF-α -308 polymorphism were associated with a reduced risk for MM. The TNF-α -238 GA+AA genotypes were associated with a significant enhancement in the progression-free survival (PFS) (P=0.009) and a better overall survival (OS) (P=0.088).


International Journal of Laboratory Hematology | 2012

Signal transducer and activator of transcription 3 (STAT3) gene polymorphisms are associated with treatment outcomes in acute myeloid leukemia

Y. Zhong; J. Feng; Chen Ba; Lu Cheng; Y. Li; J. Qian; Ding Jh; Feng Gao; Guohua Xia

Introduction:  In the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway, STAT3 is one of the most prominent prognosis factors for cancer and leukemia. STAT3 activation might promote cellular transformation and therefore have an important role in human tumors. This study aimed to investigate the relationship between STAT3 polymorphisms and treatment response of acute myeloid leukemia (AML) in the Chinese population.


Leukemia Research | 2006

Combination of tetrandrine as a potential-reversing agent with daunorubicin, etoposide and cytarabine for the treatment of refractory and relapsed acute myelogenous leukemia.

Wenlin Xu; Huiling Shen; Zhong-Fang Ao; Chen Ba; Wei Xia; Feng Gao; Yong-Ning Zhang


Journal of Experimental Hematology | 2009

Daunorubicin-loaded magnetic nanoparticles of Fe(3)O(4) greatly enhance the responses of multidrug-resistant K562 leukemic cells in a nude mouse xenograft model to chemotherapy.

Lai Bb; Chen Ba; Jian Cheng; Feng Gao; Xu Wl; Ding Jh; Gao C; Sun Xc; Li Gh; Wen-ji Chen; Liu Lj; Li Xm; Wang Xm


Journal of Experimental Hematology | 2008

[Effect of tetrandrine, toremifene and their combination on the reversion of multidrug resistance of K562/A02 cell line].

Zhao Qx; Chen Ba; Jian Cheng; Ding Jh; Feng Gao; Gao C; Sun Yy; Jun Wang; Zhao G; Bao W; Song Hh


Journal of Experimental Hematology | 2010

Effects of magnetic nanoparticle of Fe3O4 on apoptosis induced by Gambogic acid in U937 leukemia cells.

Liang Yq; Chen Ba; Wu Ww; Feng Gao; Guohua Xia; Shao Zy; Jian Cheng; Ding Jh; Gao C; Li Gh; Wen-ji Chen; Chen Nn; Xu Wl; Sun Xc; Liu Lj; Li Xm; Wang Xm


Journal of Experimental Hematology | 2005

Using protein chips to study mechanism underlying reversion of drug resistance in leukemia cells in tetrandrine alone or in combination with droloxifene

Chen Ba; Du J; Zhang Cx; Jian Cheng; Gao F; Zuhong Lu


Journal of Experimental Hematology | 2011

[Effects of hyperbaric oxygen combined with adriamycin in inducing apoptosis of K562/A02 cells].

Zhang Wj; Chen Ba; Bao W; Jian Cheng; Yujie Sun; Zhang M; Zhang Xm; Chen Y


Journal of Experimental Hematology | 2010

[Effects of hypoxia-inducible factor inhibitor on expression of HIF-1alpha and VEGF and induction of apoptosis in leukemic cell lines].

Wang F; Chen Ba; Jian Cheng; Xu Wl; Wang Xm; Ding Jh; Gao C; Sun Yy; Jun Wang; Zhao G; Bao W; Song Hh; Feng Gao; Zhang W; Guohua Xia; Pei Xp; Wu Ww; Yin L; Shan Xy


Journal of Experimental Hematology | 2009

[Effect of phenylhexyl isothiocyanate on adriamycin resistance of K562/A02 cell line].

Yuang P; Chen Ba; Cheng J; Ma Xd; Liu Dl; Lu Qy

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Ding Jh

Southeast University

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Jun Wang

Chinese Academy of Sciences

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Feng Gao

Southeast University

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Bao W

Jiangsu University

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Sun Yy

Huazhong University of Science and Technology

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Song Hh

Southeast University

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Shao Zy

Southeast University

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Xu Wl

Southeast University

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