Chennagiri R. Pandit | Researchain

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Featured researches published by Chennagiri R. Pandit.

Bioorganic & Medicinal Chemistry Letters | 2002

C-3 Amido-Indole cannabinoid receptor modulators

John Hynes; Katerina Leftheris; Hong Wu; Chennagiri R. Pandit; Ping Chen; Derek J. Norris; Bang-Chi Chen; Rulin Zhao; Peter A. Kiener; Xiaorong Chen; Lori A. Turk; Vina Patil-Koota; Kathleen M. Gillooly; David J. Shuster; Kim W. McIntyre

C-3 Amido-indoles were found to selectively bind to the CB2 receptor. SAR studies led to optimized compounds with excellent in vivo potency against LPS induced TNF-alpha release in murine models of cytokine production.

Synthetic Communications | 2002

PREPARATION OF 2-SUBSTITUTED OXAZOLES

Chennagiri R. Pandit; Richard Polniaszek; John K. Thottathil

ABSTRACT A simple and economical method for 2-substituted oxazole synthesis and its scope are described.

Archive | 2001

Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases

Katerina Leftheris; Rulin Zhao; Bang-Chi Chen; Peter A. Kiener; Hong Wu; Chennagiri R. Pandit; Stephen T. Wrobleski; Ping Chen; John Hynes; Malinda Longphre; Derek J. Norris; Steven H. Spergel

Journal of Medicinal Chemistry | 2003

Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties

Stephen T. Wrobleski; Ping Chen; John Hynes; Shuqun Lin; Derek J. Norris; Chennagiri R. Pandit; Steven H. Spergel; Hong Wu; John S. Tokarski; Xiaorong Chen; Kathleen M. Gillooly; Peter A. Kiener; Kim W. McIntyre; Vina Patil-Koota; David J. Shuster; Lori A. Turk; Guchen Yang; Katerina Leftheris

Archive | 2000

Methods for the preparation of biphenyl isoxazole sulfonamides

Richard Polniaszek; Xuebao Wang; Jeffrey S. DePue; Chennagiri R. Pandit; Kumar G. Gadamasetti; Yadagiri Pendri; Eduardo J. Martinez

Heterocycles | 2001

A General Large Scale Synthesis of 2-Alkyl-7-methoxyindoles

Bang-Chi Chen; John Hynes; Chennagiri R. Pandit; Rulin Zhao; Amanda P. Skoumbourdis; Hong Wu; Joseph E. Sundeen; Katerina Leftheris

Archive | 2002

HIGH MELT POLYMORTH OF THE COMPOUND N-(3,4-DIMETHYL-5-ISOXAZOLYL)-4'- (2-OXAZOLYL) [1,1'-BIPHENYL]-2-SULFONAMIDE

Richard Polniaszek; Xuebao Wang; Jeffrey S. DePue; Chennagiri R. Pandit; Kumar G. Gadamasetti; Yadagiri Pendri; Eduardo J. Martinez

Archive | 2002

PINACOL ESTER INTERMEDIATES USEFUL FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES

Richard Polniaszek; Xuebao Wang; Jeffrey S. DePue; Chennagiri R. Pandit; Kumar G. Gadamasetti; Yadagiri Pendri; Eduardo J. Martinez

Archive | 2002

PROCESS FOR PREPARING BIPHENYL ISOXAZOLE SULFONAMIDE INTERMEDIATES

Richard Polniaszek; Xuebao Wang; Jeffrey S. DePue; Chennagiri R. Pandit; Kumar G. Gadamasetti; Yedagiri Pendri; Eduardo J. Martinez

Archive | 2001

Modulateurs de recepteurs aux cannabinoides, leurs procedes de preparation et utilisations de modulateurs de recepteurs aux cannabinoides pour le traitement de maladies respiratoires et non respiratoires

Katerina Leftheris; Rulin Zhao; Bang-Chi Chen; Peter A. Kiener; Hong Wu; Chennagiri R. Pandit; Stephen T. Wrobleski; Ping Chen; John Hynes; Malinda Longphre; Derek J. Norris; Steven H. Spergel; John S. Tokarski

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