Cheol-Lae Roh

P15.09: Association of abnormal vaginal colonisation and preterm delivery: effect of cervical length: Poster discussion hub abstracts

•Ascending migration of abnormal microorganisms from the female genital tract is considered to be the most important route of bacterial spread, leading to intrauterine infection in preterm gestation. However, the exact relationship between abnormal vaginal colonization and adverse pregnancy outcome in preterm labor (PTL) remains unclear. Therefore, we hypothesized that women with shorter cervical length (CL) are predisposed to ascending infection compared to those with longer CL in women with preterm labor or short CL.

OP04.04: Prenatally diagnosed fetal congenital cystic adenomatoid malformation (CCAM) and bronchopulmonary sequestration (BPS) showed excellent survival and prognosis: a 10-year review in a tertiary hospital

Objectives: To find prognostic factors of antenatally diagnosed congenital cystic adenomatoid malformation (CCAM) and bronchopulmonary sequestration (BPS) by analysing the pregnancy outcomes. Methods: Retrospective analyses were carried out for antenatally diagnosed fetal CCAM (77 cases) and fetal BPS (21 cases) at our institution from July 2005 to May 2015. Demographic characteristics, sonographic findings, postnatal diagnoses and pregnancy outcomes were collected from medical records and analysed. Diagnoses were confirmed postnatally by imaging studies and pathologic findings. Results: A total of 98 cases were prenatally diagnosed as CCAM (77 cases) and BPS (21 cases) during the study period. In 44 cases (44.9%) who followed up and delivered in our institution, one fetal intrauterine death (2.3%) occurred in a dichorionic diamniotic twin due to progression of fetal hydrops. Among 43 live births, 20 cases of CCAM and 5 cases of BPS were diagnosed postnatally and the others showed spontaneous regression of thoracic mass. The concordance rate between antenatal and postnatal diagnosis was 80%. From 21 cases who showed spontaneous regression of CCAM (17 cases) or BPS (4 cases) on antenatal sonography, three cases were diagnosed as CCAM postnatally. Postnatal surgery was done in eight cases (18.6%) including one case of catheterisation. Location of mass, mediastinal shift, hydrops, polyhydramnios and associate anomaly were not associated with size decrease of mass, spontaneous regression of mass and postnatal operation. Conclusions: Prenatally diagnosed CCAM and BPS showed excellent survival and prognosis irrespective of sonographic findings including the location and size of mass. One case of intrauterine fetal death was observed due to progression of fetal hydrops in a dichorionic diamniotic twin. Postnatal surgery was necessary in less than 20% of cases.